Prescription onlyLower-cost generic available

Amiloride / Hydrochlorothiazide

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Lowers blood pressure. Removes extra water from your body.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Amiloride / Hydrochlorothiazide can remove excess fluids and lower your blood pressure while keeping your potassium levels steady.

  • Lowers the risk of heart attack and stroke.
  • Lowers the risk of muscle problems from low potassium.
  • Gets rid of extra fluids in your body.
  • Helpful for people who tend to have low potassium levels.
  • Not the first choice medicine to lower blood pressure or remove extra fluids from your body.
  • Will make you urinate more often.
  • Can make you sensitive to sunlight.
  • Use with caution if you diabetes or kidney problems.
  • Needs at least a yearly blood test to monitor electrolytes and kidney function.
  • Shouldn't take it if you have a sulfa allergy.
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Side effects for Amiloride / Hydrochlorothiazide

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These are side effects of Amiloride / Hydrochlorothiazide reported to the FDA by people taking it, and by doctors and pharmacists.

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What to expect when you take Amiloride / Hydrochlorothiazide

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Tips from our pharmacists
  • Makes you urinate more often, so don't take it at bedtime.
  • Can make you feel dizzy the first few days, but should improve as your body gets used to the medicine.
  • Get your blood pressure, potassium, and kidney function checked one week after starting the medicine, then routinely after.
  • Tell your doctor about any dizziness or muscle weakness that doesn't go away.
  • Can make your skin more sensitive to sun, use proper protections.

Risks and Warnings for Amiloride / Hydrochlorothiazide

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    • Higher risk if:
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
    • Diabetes

    Amiloride / Hydrochlorothiazide can increase the amount of potassium in your body. High potassium can cause heart problems. Baseline and routine blood tests are needed to monitor your potassium and kidney function.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Amiloride / Hydrochlorothiazide

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The FDA category for this medication is B. It is advised that you: Probably safe
Pregnancy
Kidneys & liver
  • Upsides and downsides from our pharmacists
  • Use with caution if you diabetes or kidney problems.
  • Needs at least a yearly blood test to monitor electrolytes and kidney function.
  • Tips from our pharmacists
  • Get your blood pressure, potassium, and kidney function checked one week after starting the medicine, then routinely after.
  • Risks from our pharmacists
  • Amiloride / Hydrochlorothiazide can increase the amount of potassium in your body. High potassium can cause heart problems. Baseline and routine blood tests are needed to monitor your potassium and kidney function.
  • Amiloride / Hydrochlorothiazide can affect levels of certain electrolytes (sodium, magnesium) that can cause muscle weakness/spasms or unexplained tiredness. Baseline and routine blood tests are needed to monitor your electrolytes and kidney function.