Amitiza

(lubiprostone)

Skip to: what to expect sectionSkip to: side effects sectionSkip to: risks and warnings sectionSkip to: common concerns from users and pharmacists

Treats constipation.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Amitiza (lubiprostone) is a good but expensive option to treat severe constipation if other medications did not work for you.

Quick facts about Amitiza
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: No lower cost generic available
Prices and discounts
Lowest price for 60 24mcg capsules
Determining your location...
$367.94
  • Price before coupon
    $469.68
  • Lowest price with coupon
    $367.94
  • Savings
    22%

Upsides

  • Amitiza (lubiprostone) works well for severe constipation that has not responded to other medications.
  • Amitiza (lubiprostone) can help improve bowel habit, reduce straining, and improve stool consistency.

Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Amitiza, on one page

Download Fact Sheet
Tried Amitiza? Write a review!

Downsides

  • Amitiza (lubiprostone) is not available as a generic and may be more expensive than alternatives.
  • Amitiza (lubiprostone) has not been adequately tested in people who have constipation from cancer or cancer treatment.
  • People with liver problems should be careful when taking Amitiza (lubiprostone).

Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Amitiza, on one page

Download Fact Sheet
Prices and discounts
Lowest price for 60 24mcg capsules
Determining your location...
$367.94
  • Price before coupon
    $469.68
  • Lowest price with coupon
    $367.94
  • Savings
    22%
How it works

Amitiza (lubiprostone) is a chloride channel activator that brings more fluid to the intestines so stool can pass more loosely and easily.

Quick facts about Amitiza
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

Dosage forms

  • Pill
Tried Amitiza? Write a review!

What to expect when you take Amitiza (lubiprostone) for Constipation

Skip what to expect section. Skip to side effects section.
Skip side effects section. Skip to risks and warnings section.

Side effect rates for Amitiza (lubiprostone)

From 1429 clinical trials of Amitiza when taken for chronic idiopathic constipation
  • Diarrhea
  • Headache
  • Abdominal pain
  • Abdominal bloating
  • Gas
  • Vomiting
  • Loose stools
  • Abdominal discomfort
  • Dizziness
  • Swelling
  • Indigestion
  • Fatigue
  • Chest discomfort/pain
  • Shortness of breath

Risks and Warnings for Amitiza (lubiprostone)

Skip risks section. Skip to common concerns section.
  • Some people experience nausea when taking Amitiza (lubiprostone). Taking it with food can help prevent nausea.

Pharmacist Q&A

Amitiza (lubiprostone) questions for

Frequently Asked Questions

This medication treats chronic idiopathic constipation in adults.

Who is this drug for?

This medication treats chronic idiopathic constipation in adults.

Common concerns from people taking Amitiza (lubiprostone)

Final section. Do you want to return to drug navigation?
Food
  • Some people experience nausea when taking Amitiza (lubiprostone). Taking it with food can help prevent nausea.
  • Take Amitiza (lubiprostone) with food and a full glass of water.
  • Avoiding foods that cause gas or that contain lactose and gluten can help constipation in certain people. Talk to your doctor or pharmacist if you have questions.
Kidneys and liver
  • If you have liver disease, talk to your doctor before starting Amitiza (lubiprostone) as you're more likely to have side effects. You might have to start on a lower dose.
Now you can ask a pharmacist!

What is your question about?

Your question

Your email

We need your email to send you an answer.

Disclaimer: We don't provide medical advice. If you think you might have a medical emergency, call your doctor or 911 immediately.