Relieves hot flashes and vaginal dryness due to menopause.
Our pharmacists’ bottom line
Angeliq (Drospirenone / Estradiol) effectively relieves menopausal symptoms. There can be many side effects, so it's important to think through the benefits and potential hassles of this drug before using it.
- Angeliq (Drospirenone / Estradiol) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen (hot flashes, night sweats, vaginal dryness).
- Improves mood, energy, and mental alertness for some people.
- Good for women with an intact uterus. The drospirenone (a progestin) protects against the risk of cancer in the uterus from estrogen treatment.
- Decreased bloating and possible weight loss from the drospirenone, which has diuretic properties (helps your body get rid of water through urination).
- More potential side effects since it exposes your whole body to two hormones, estrogen and drospirenone (a progestin).
- Increases your risk of developing blood clots and stroke.
- You may get irregular bleeding and spotting that can last a few months to a year.
- Has a slightly higher risk of blood clots compared to other estrogen-progestin combination pills because of the type of progestin it contains (drospirenone).
- Must be used carefully with any other medicine that can increase your potassium level.
Save on your next Angeliq (Drospirenone / Estradiol) prescription
Get the lowest price for your medication, even if you have insurance.
- (1) 28 tablets of 0.5mg/1mg package
- Cost for (1) 28 tablets of 0.5mg/1mg package of Angeliq (Drospirenone / Estradiol) at pharmacies
Side effects for Angeliq (Drospirenone / Estradiol)
From clinical trials of Angeliq / Postmenopausal hormone replacement (0.25/0.5 mg) ( 363)
- Gastrointestinal and abdominal painsGastrointestinal and abdominal pains6% for Angeliq vs.3% for placebo
- HeadacheHeadache6% for Angeliq vs.5% for placebo
- Vulvovaginal fungal infectionsVulvovaginal fungal infections6% for Angeliq vs.1% for placebo
- Breast painBreast pain3% for Angeliq vs.1% for placebo
- NauseaNausea3% for Angeliq vs.1% for placebo
- DiarrheaDiarrhea2% for Angeliq vs.1% for placebo
- Leg or ankle swellingLeg or ankle swelling2% for Angeliq vs.1% for placebo
What to expect when you take Angeliq (Drospirenone / Estradiol)Skip what to expect section. Skip to Risks & Warnings section.
- You can get some bleeding if you miss several doses in a row.
- Shouldn't be used forever. Talk to your doctor regularly to see if you still need treatment.
- Can cause nausea, dizziness, and breast tenderness.
- Tell your doctor about any unusual vaginal bleeding.
- Get emergency care if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision.
Risks and Warnings for Angeliq (Drospirenone / Estradiol)Skip Risks and Warnings section. Skip to Tips section.
- Higher risk if:
- › Using estrogen for more than one year
Vaginal bleeding after menopause can be a warning sign of uterus (endometrial) cancer, so let your doctor know if you notice any unusual bleeding. When estrogen is prescribed to women after menopause who still have a uterus, progestin should be used with it to lower the risk of cancer. Low-dose vaginal estrogen products are often a better choice than oral pills for women 65 years or older who have vaginal symptoms.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.
Tips from pharmacists and people taking Angeliq (Drospirenone / Estradiol)Final section. Do you want to return to drug navigation?
- Upsides and downsides from our pharmacists
- › Decreased bloating and possible weight loss from the drospirenone, which has diuretic properties (helps your body get rid of water through urination).