Treats inflammatory bowel disease.
Our bottom line
Lialda (Mesalamine) is an effective first-line medicine for inflammatory bowel disease. There isn't a generic version and you'll have to take it multiple times a day.
- Effective first-line medication for treating and lowering the symptoms of mild inflammatory bowel disease.
- About half the people who have mild to moderate colon inflammation and take Lialda (Mesalamine) will see improvement.
- Available in tablets, capsules, enemas, and suppositories.
- Certain forms of Lialda (Mesalamine) can be used during pregnancy. Talk to your doctor if you're pregnant, or plan on becoming pregnant, and you want to take Lialda (Mesalamine).
- No generic versions are available for the tablets, capsules, and suppositories (meaning it could be somewhat expensive).
- Doesn't work well for severe colon inflammation.
- You may need to take Lialda (Mesalamine) three or four times a day.
- Not a good option if you have kidney disease.
What to expect when you take Lialda (Mesalamine) for Ulcerative colitisSkip what to expect section. Skip to Risks & Warnings section.
- Don't take Lialda (Mesalamine) if you're allergic to aspirin. Talk to your doctor or pharmacist about any drug allergies you have before starting Lialda (Mesalamine).
- Taking antacids with Lialda (Mesalamine) can make your inflammation worse. Talk to your doctor before you make any changes.
- You can sunburn more easily when taking Lialda (Mesalamine). Use sunscreen and protective clothing when you go outdoors.
- Don't break, chew, or crush the tablets because they're coated and won't work as well.
- The suppositories should be kept in for at least 1 to 3 hours to get the most benefit.
Side effects for Lialda (Mesalamine)
From clinical trials of Asacol / Ulcerative colitis ( 239)
- HeadacheHeadache35% for Mesalamine vs.36% for placebo
- Abdominal painAbdominal pain18% for Mesalamine vs.14% for placebo
- EructationEructation16% for Mesalamine vs.15% for placebo
- PainPain14% for Mesalamine vs.8% for placebo
- NauseaNausea13% for Mesalamine vs.15% for placebo
- Sore throatSore throat11% for Mesalamine vs.9% for placebo
- DizzinessDizziness8% for Mesalamine vs.8% for placebo
- Muscle weaknessMuscle weakness7% for Mesalamine vs.15% for placebo
- Back painBack pain7% for Mesalamine vs.5% for placebo
- DiarrheaDiarrhea7% for Mesalamine vs.9% for placebo
Risks and Warnings for Lialda (Mesalamine)Skip Risks and Warnings section. Skip to Tips section.
- Higher risk if:
- › Asthma
- › Rhinitis
- › Nasal polyps
- › Aspirin allergy
- › NSAID allergy
Rarely, Lialda (Mesalamine) can cause serious allergic reactions. These reactions can make it difficult to breathe or cause a severe rash that can be life-threatening. Stop taking Lialda (Mesalamine) and report any skin rash, fever, swelling, or trouble breathing to a doctor right away.
Tips from pharmacists and people taking Lialda (Mesalamine)Final section. Do you want to return to drug navigation?
- These tend to be very large pills, and you take a lot of them daily. Setting a reminder for when to take them, or 2 with each meal helps. Definitely worth the trouble.
- Large pills that are not difficult to take. Take just before meals.
- Best to take it all at once with your biggest meal of the day
- Upsides and downsides from our pharmacists
- › Not a good option if you have kidney disease.
- Risks from our pharmacists
- › Lialda (Mesalamine) is broken down by the kidney and liver. If you have kidney or liver problems, talk to your doctor because you may need to take a different dose of the medication.