Prescription onlyLower-cost generic availableClass: Gastrointestinal

Lialda 

(mesalamine)

Prescription onlyLower-cost generic availableClass: Gastrointestinal
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Treats inflammatory bowel disease.

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Our bottom line

Lialda (Mesalamine) is an effective first-line medicine for inflammatory bowel disease. There isn't a generic version and you'll have to take it multiple times a day.

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Upsides

  • Effective first-line medication for treating and lowering the symptoms of mild inflammatory bowel disease.
  • About half the people who have mild to moderate colon inflammation and take Lialda (Mesalamine) will see improvement.
  • Available in tablets, capsules, enemas, and suppositories.
  • Certain forms of Lialda (Mesalamine) can be used during pregnancy. Talk to your doctor if you're pregnant, or plan on becoming pregnant, and you want to take Lialda (Mesalamine).

Downsides

  • No generic versions are available for the tablets, capsules, and suppositories (meaning it could be somewhat expensive).
  • Doesn't work well for severe colon inflammation.
  • You may need to take Lialda (Mesalamine) three or four times a day.
  • Not a good option if you have kidney disease.
How it works

Lialda (Mesalamine) is an anti-inflammatory medication. Researchers don't know exactly how Lialda (Mesalamine) works in the colon, but it seems to lower the chemicals in the body that cause inflammation.

What to expect when you take Lialda (mesalamine) for Ulcerative colitis

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Side effect rates for Lialda (mesalamine)

239 From clinical trials of Asacol / Ulcerative colitis
  • Headache
  • Abdominal pain
  • Eructation
  • Pain
  • Nausea
  • Sore throat
  • Dizziness
  • Muscle weakness
  • Back pain
  • Diarrhea

Risks and Warnings for Lialda (mesalamine)

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    • Higher risk if:
    • Asthma
    • Rhinitis
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy

    Rarely, Lialda (Mesalamine) can cause serious allergic reactions. These reactions can make it difficult to breathe or cause a severe rash that can be life-threatening. Stop taking Lialda (Mesalamine) and report any skin rash, fever, swelling, or trouble breathing to a doctor right away.

Common concerns from people taking Lialda (mesalamine)

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Pregnancy
Food
  • Best to take it all at once with your biggest meal of the day
Kidneys and liver
  • Not a good option if you have kidney disease.
  • Lialda (Mesalamine) is broken down by the kidney and liver. If you have kidney or liver problems, talk to your doctor because you may need to take a different dose of the medication.
  • Rarely, Lialda (Mesalamine) can cause liver injury, hepatitis, and liver failure. Let your doctor know and get medical attention if you notice yellowing skin or eyes.