Prescription onlyNo lower cost generic available



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Treats relapsing forms of MS.

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Prescription onlyNo lower cost generic available

Our pharmacists’ bottom line

Aubagio (Teriflunomide) is an oral medicine that effectively reduces the number of flare-ups, slows physical changes, and decreases the number of new brain lesions in relapsing MS. Because it stays in the body for so long, if you have a serious reaction or possible pregnancy you'll need to have it quickly removed with another medicine.

  • You can take it by mouth.
  • It comes a 7 mg and 14mg dose and only needs to be taken once a day, with or without food.
  • In clinical studies, Aubagio reduced relapses, slowed disability, and decreased the number of new brain lesions compared to sugar pill (placebo).
  • Although it may not work for everyone, most people felt it wasn't much of a hassle.
  • Some people have nausea and diarrhea when they start treatment. In most cases, these effects are mild and get better over time.
  • Aubagio can cause your hair to thin. This is temporary, and your hair will go back to normal after a few months.
  • You should have certain lab tests to make sure you don't have any problems from taking Aubagio. These include: complete blood count and liver enzyme testing within 6 months before you start treatment, tuberculosis (TB) screening, and blood pressure.
  • Numbness or tingling in your hands and feet (peripheral neuropathy), different from MS was reported more often than with sugar pill (placebo)
  • Aubagio may stay in your blood up to 2 years after you stop taking it. You can quickly remove Aubagio the accelerated elimination procedure, but symptoms of your disease may return.
  • You can't take it if you're pregnant.

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Side effects for Aubagio (Teriflunomide)

From clinical trials of Aubagio / Multiple sclerosis 

  • Mild hypophospatemiaMild hypophospatemia18% for Aubagio vs.9% for placebo

Manufacturers don’t say how common these side effects are

  • Cardiovascular death

What to expect when you start Aubagio (Teriflunomide)

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Tips from our pharmacists
  • Take one capsule daily with or without food.
  • It's very important you read the Aubagio Medication Guide.
  • Most common side effects are diarrhea, nausea, hair thinning, and elevated liver blood levels.
  • Not the best choice if you have liver problems or are on medications that affect the liver.
  • Liver blood tests need to be done for 6 months once you start taking Aubagio. If these tests are abnormal and liver damage is suspected your doctor will stop the medicine and tell you to start taking cholestyramine for 11 days to lower the toxic level.
  • You'll need to have a TB test before you start taking Aubagio.
  • Can cause numbness and tingling of your hands and feet. Let your doctor know if this becomes a problem.
  • Aubagio increases your risk of infections so tell your doctor if you notice a fever, cough that doesn't go away, or flu-like symptoms. Get your blood counts checked 6 months before starting treatment.
  • Aubagio can also cause serious and life-threatening liver, lung, skin, kidney and blood pressure effects.
  • Aubagio will harm your unborn baby and is pregnancy category X. You must have a negative pregnancy test before starting Aubagio.
  • Both men and women are affected. If they want to have a baby both need to stop taking Aubagio and begin rapid removal process using cholestyramine or activated charcoal for 11 days. Without this process, Aubagio will stay in the body for up to 2 years.

Risks and Warnings for Aubagio (Teriflunomide)

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    • Higher risk if:
    • Taking medicines that affect your liver or cause liver injury

    Aubagio (Teriflunomide) may cause serious liver problems, which can be life-threatening. Your risk is higher if you take other medicines that affect your liver. Tell your doctor right away if you have nausea, vomiting, stomach pain, loss of appetite, tiredness, yellowing of your skin/whites of your eyes, or dark urine. You should have blood tests to check your liver function 6 months before you start taking Aubagio (Teriflunomide) then every month for 6 months after.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Aubagio (Teriflunomide)

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The FDA category for this medication is X. It is advised that you: Unsafe
  • Upsides and downsides from our pharmacists
  • It comes a 7 mg and 14mg dose and only needs to be taken once a day, with or without food.
  • Tips from our pharmacists
  • Take one capsule daily with or without food.
Kidneys & liver
  • Tips from our pharmacists
  • Aubagio can also cause serious and life-threatening liver, lung, skin, kidney and blood pressure effects.
  • Risks from our pharmacists
  • People taking Aubagio (Teriflunomide) had temporary acute kidney failure thought to be due to high uric acid buildup in the kidneys (uric acid nephropathy). Kidney function started to decrease from 12 weeks to 2 years after the first dose, then returned to normal with continued dosing. It’s not completely clear is there were other reasons for this effect and people generally didn't have any symptoms.
  • Aubagio (Teriflunomide) has caused high blood potassium levels in people that also had acute kidney failure. Your doctor will do tests to check your potassium levels especially if you already have kidney problems.