Prescription onlyClass: Autoimmune



Prescription onlyClass: Autoimmune
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Treats relapsing forms of MS.

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Our bottom line

Aubagio (Teriflunomide) is an oral medicine that effectively reduces the number of flare-ups, slows physical changes, and decreases the number of new brain lesions in relapsing MS. Because it stays in the body for so long, if you have a serious reaction or possible pregnancy you'll need to have it quickly removed with another medicine.

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Prices and coupons for 3 (28 tablets of 14mg) packages of aubagio
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  • You can take it by mouth.
  • It comes a 7 mg and 14mg dose and only needs to be taken once a day, with or without food.
  • In clinical studies, Aubagio reduced relapses, slowed disability, and decreased the number of new brain lesions compared to sugar pill (placebo).
  • Although it may not work for everyone, most people felt it wasn't much of a hassle.
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  • Some people have nausea and diarrhea when they start treatment. In most cases, these effects are mild and get better over time.
  • Aubagio can cause your hair to thin. This is temporary, and your hair will go back to normal after a few months.
  • You should have certain lab tests to make sure you don't have any problems from taking Aubagio. These include: complete blood count and liver enzyme testing within 6 months before you start treatment, tuberculosis (TB) screening, and blood pressure.
  • Numbness or tingling in your hands and feet (peripheral neuropathy), different from MS was reported more often than with sugar pill (placebo)
  • Aubagio may stay in your blood up to 2 years after you stop taking it. You can quickly remove Aubagio the accelerated elimination procedure, but symptoms of your disease may return.
  • You can't take it if you're pregnant.
How it works

Aubagio (Teriflunomide) is an immune modulator. Researchers don't know exactly how it works for MS, but it seems to lower your white blood cells and keep them from attacking the nerves in your brain and spinal cord.

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Side effect rates for Aubagio (teriflunomide)

  • Moderate hypophospatemia

Risks and Warnings for Aubagio (teriflunomide)

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    • Higher risk if:
    • Taking medicines that affect your liver or cause liver injury

    Aubagio (Teriflunomide) may cause serious liver problems, which can be life-threatening. Your risk is higher if you take other medicines that affect your liver. Tell your doctor right away if you have nausea, vomiting, stomach pain, loss of appetite, tiredness, yellowing of your skin/whites of your eyes, or dark urine. You should have blood tests to check your liver function 6 months before you start taking Aubagio (Teriflunomide) then every month for 6 months after.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Aubagio (teriflunomide)

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  • Aubagio increases your risk of infections so tell your doctor if you notice a fever, cough that doesn't go away, or flu-like symptoms. Get your blood counts checked 6 months before starting treatment.
  • It comes a 7 mg and 14mg dose and only needs to be taken once a day, with or without food.
  • Take one capsule daily with or without food.
Kidneys and liver
  • Not the best choice if you have liver problems or are on medications that affect the liver.
  • Liver blood tests need to be done for 6 months once you start taking Aubagio. If these tests are abnormal and liver damage is suspected your doctor will stop the medicine and tell you to start taking cholestyramine for 11 days to lower the toxic level.
  • Aubagio (Teriflunomide) has caused high blood potassium levels in people that also had acute kidney failure. Your doctor will do tests to check your potassium levels especially if you already have kidney problems.