3.3/ 7 average rating with 23 reviewsforAubagio



Aubagio (Teriflunomide)

Prescription only

Avonex (Interferon Beta-1A)

Prescription only
1 of 5 alternatives
Treats relapsing forms of MS.

Aubagio (Teriflunomide) is an oral medicine that effectively reduces the number of flare-ups, slows physical changes, and decreases the number of new brain lesions in relapsing MS. Because it stays in the body for so long, if you have a serious reaction or possible pregnancy you'll need to have it quickly removed with another medicine.

Lowers the frequency of multiple sclerosis exacerbations.

Avonex (Interferon Beta-1A) is an injectable medicine effective for relapsing, remitting MS and has manageable side effects and weekly dosing.

  • You can take it by mouth.
  • It comes a 7 mg and 14mg dose and only needs to be taken once a day, with or without food.
  • In clinical studies, Aubagio reduced relapses, slowed disability, and decreased the number of new brain lesions compared to sugar pill (placebo).
  • Although it may not work for everyone, most people felt it wasn't much of a hassle.
  • One of the main treatments for relapsing MS that has been around for many years.
  • Injections are given weekly, and not daily like other MS medications.
  • Helps reduce the frequency of MS relapse episodes.
  • Flu-like reactions are the most common side effects and usually go away with continued treatment or can be avoided by using over-the-counter pain and fever-reducing medicines before the injection (like acetaminophen or ibuprofen).
  • Some people have nausea and diarrhea when they start treatment. In most cases, these effects are mild and get better over time.
  • Aubagio can cause your hair to thin. This is temporary, and your hair will go back to normal after a few months.
  • You should have certain lab tests to make sure you don't have any problems from taking Aubagio. These include: complete blood count and liver enzyme testing within 6 months before you start treatment, tuberculosis (TB) screening, and blood pressure.
  • Numbness or tingling in your hands and feet (peripheral neuropathy), different from MS was reported more often than with sugar pill (placebo)
  • Aubagio may stay in your blood up to 2 years after you stop taking it. You can quickly remove Aubagio the accelerated elimination procedure, but symptoms of your disease may return.
  • You can't take it if you're pregnant.
  • Injection site reactions are common, ranging from localized pain, redness, and swelling to severe skin dryness.
  • Flu-like symptoms are common after interferon injections.
  • It's not clear what type of problems occur if taken during pregnancy.
  • Blood testing is required before and during use of Avonex (Interferon Beta-1A).
  • May not be as effective as other interferons.
Used for
Dosage forms
  • Pill
  • Injection
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Side effects
1possible side effects
  • Moderate hypophospatemia
See more detailed side effects
10possible side effects
  • Headache
  • Flu-like symptoms
  • Myalgia
  • Asthenia
  • Pain
  • Nausea
  • Fever
  • Chills
  • Depression
  • Urinary tract infection
See more detailed side effects
Risks and warnings
  • Liver problems

    Taking medicines that affect your liver or cause liver injury

  • Serious skin reactions

    Reaction to leflunomide

  • Numbness in extremities (hands and feet)

    Age 60 or older

    ...and 2 more risk factors

  • Serious Infections

    Taking other immunosuppressant drugs

    ...and 2 more risk factors

  • Kidney problems

    High uric acid levels

  • High potassium

    Acute kidney failure

  • Respiratory problems

    History of lung disease

  • High blood pressure

    History of high blood pressure

See more detailed risks and warnings
  • Suicidal thoughts or behavior

    History of depression or mental illness

  • Serious allergic reaction

    Allergy to albumin

    ...and 1 more risk factors

  • Liver damage

    Alcohol use

    ...and 2 more risk factors

  • Heart problems

    History of heart disease

  • Seizures

    History of seizures

  • Risk to fetus

    Women of childbearing age

See more detailed risks and warnings