Prescription onlyClass: Cancer

Avastin 

(bevacizumab)

Prescription onlyClass: Cancer
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Treats certain types of cancers.

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Our bottom line

Avastin (Bevacizumab) is an effective, first-line option when used together with other medicines for certain types of cancers, but it has to be given in a clinic or hospital and it has many severe side effects.

Price and discounts
Best available price for 1 (4ml of 100mg/4ml) vial of bevacizumab

Upsides

  • In studies, taking Avastin (Bevacizumab) with other chemotherapy (anti-cancer) medicines extended the lives of people with certain types of cancers better than not taking Avastin (Bevacizumab).
  • Treats brain, cervical, colorectal, lung, and kidney cancers.
  • Avastin (Bevacizumab) is used as a first- or second-line choice along with other medicines for certain types of cancers.
  • Avastin (Bevacizumab) is typically given every 2 to 3 weeks and can be given along with other chemotherapy (anti-cancer) medicines during the same visit.

Downsides

  • Not the best choice if you have heart or kidney problems.
  • Avastin (Bevacizumab) can damage the ovaries. Talk to your doctor before starting Avastin (Bevacizumab) if you're concerned about getting pregnant.
  • It may take longer for you to heal. Avastin (Bevacizumab) shouldn't be used for 28 days before and after surgery.
  • There's no generic available and it can be very expensive.
How it works

Avastin (Bevacizumab) is a monoclonal antibody. It binds to an important factor that blocks the blood supply to a tumor and stops the growth of cancer.

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Side effect rates for Avastin (bevacizumab)

163 From clinical trials of Avastin / Brain cancer
  • Infection
  • Fatigue
  • Headache
  • High blood pressure
  • Diarrhea
  • Nosebleed
  • Any side effect
  • Wound healing/bleeding complications

Risks and Warnings for Avastin (bevacizumab)

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  • Avastin (Bevacizumab) can cause a hole to develop in your stomach or intestine. Talk to your doctor if you experience pain in your abdomen, nausea, vomiting, constipation, or fever.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Avastin (bevacizumab)

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Pregnancy
Kidneys and liver
  • Treats brain, cervical, colorectal, lung, and kidney cancers.
  • Not the best choice if you have heart or kidney problems.
  • Avastin (Bevacizumab) can cause kidney problems due to too much protein in your urine. Talk to your doctor about getting regular kidney tests while taking Avastin (Bevacizumab).