Prescription onlyClass: Men's Health

Axiron Alternatives

(testosterone topical solution)

Prescription onlyClass: Men's Health
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Compare Axiron (testosterone topical solution) to alternatives

These medications are comparable to Axiron (testosterone topical solution) or used for similar purposes.

Axiron
(testosterone topical solution)

Androderm
(testosterone patch)

Androgel
(testosterone gel)

Fortesta
(testosterone gel)

Testim
(testosterone gel)

Delatestryl
(testosterone enanthate injection)

Depo-Testosterone
(testosterone cypionate injection)

Aveed
(testosterone undecanoate injection)

Treats low testosterone. This testosterone topical solution is a convenient topical form of hormone replacement that's less likely to rub off on other people you come into contact with, but it's not available as a generic yet.Treats low testosterone. The testosterone patch is a topical form of hormone replacement that doesn't affect people you come in contact with, but it can cause skin irritation so you have to rotate its position every night.Treats low testosterone. This testosterone gel is a convenient topical form of hormone replacement, but you have to be careful about it rubbing off on other people. Also it can be cheaper than alternatives.Treats low testosterone. This testosterone gel is a convenient topical form of hormone replacement that's less likely to rub off on other people you come into contact with, but it's not available as a generic yet.Treats low testosterone. This testosterone gel comes in convenient daily doses, but you have to be careful about skin-to-skin contact with other people.Treats low testosterone. This testosterone injection only has to be given once or twice a month and you can do it at home, but someone has to help you inject.Treats low testosterone. This testosterone injection only has to be given once or twice a month and you can do it at home, but someone has to help you inject.Treats low testosterone. This testosterone injection is a first-choice treatment, but you have to get it in your doctor's office each time.
Reviews & ratings
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Have you used Axiron (testosterone topical solution)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Androderm (testosterone patch)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Androgel (testosterone gel)?
Worth itNot sureNot worth it

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Have you used Fortesta (testosterone gel)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Testim (testosterone gel)?
Worth itNot sureNot worth it
Reviews for Delatestryl
43%
+24% better vs. Axiron
21%
+46% better vs. Axiron
27%
+10% better vs. Axiron
103 reviews
Have you used Delatestryl (testosterone enanthate injection)?
Worth itNot sureNot worth it
Reviews for Depo-Testosterone
49%
+18% better vs. Axiron
32%
+35% better vs. Axiron
17%
Same vs. Axiron
100 reviews
Have you used Depo-Testosterone (testosterone cypionate injection)?
Worth itNot sureNot worth it
Reviews for Aveed
41%
+26% better vs. Axiron
22%
+45% better vs. Axiron
18%
+1% better vs. Axiron
Have you used Aveed (testosterone undecanoate injection)?
Worth itNot sureNot worth it
Side effects
AxironAndrodermAndrogelFortestaTestimDelatestrylDepo-TestosteroneAveed
  • Application Site Irritation 8%
  • Hematocrit Increased 7%
  • Application Site Erythema 7%
  • Headache 6%
  • Diarrhea 4%
  • Vomiting 4%
  • PSA Increased 4%
More Axiron side effects »
  • Any appication site reaction 28%
  • Application site pruritus 17%
  • Application site vesicles 6%
  • Back pain 6%
  • Application site erythema 3%
  • Application site exfoliation 3%
  • Chills 3%
  • Prostatitis 3%
  • Fatigue 3%
  • Gastroesophageal reflux disease 3%
More Androderm side effects »
  • PSA increased 11%
  • Any adverse reaction 11%
  • Emotional lability 3%
  • Hypertension 2%
  • Hematocrit or hemoglobin increased 2%
  • Contact dermatitis 2%
More Androgel side effects »
  • Skin reaction 16%
More Fortesta side effects »
  • Increase in hematocrit (≥ 58%) 1%
  • Hematocrit/hemoglobin Increased 2%
  • Increase in hemoglobin (≥ 19 g/dL) 1%
More Testim side effects »

The Delatestryl FDA package insert doesn’t have numbers about how common side effects are.

More about Delatestryl side effects »

The Depo-Testosterone FDA package insert doesn’t have numbers about how common side effects are.

More about Depo-Testosterone side effects »
  • Acne 5%
  • Injection site pain 5%
  • Prostatic specific antigen increased 5%
  • Estradiol increased 3%
  • Hypogonadism 3%
  • Fatigue 2%
  • Irritability 2%
  • Hemoglobin increased 2%
  • Insomnia 2%
  • Mood swings 2%
More Aveed side effects »
How it works
AxironAndrodermAndrogelFortestaTestimDelatestrylDepo-TestosteroneAveed
Testosterone topical solution works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.The testosterone patch works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.Testosterone gel works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.Testosterone gel works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.Testosterone gel works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.The testosterone injection works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on. Also, it can slow the spread of certain kinds of breast cancer.The testosterone injection works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.The testosterone injection works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.
Type of medication
AxironAndrodermAndrogelFortestaTestimDelatestrylDepo-TestosteroneAveed
Prescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription only
Available as
AxironAndrodermAndrogelFortestaTestimDelatestrylDepo-TestosteroneAveed
  • Topical
  • Patch
  • Cream, gel, or ointment
  • Cream, gel, or ointment
  • Cream, gel, or ointment
  • Injection
  • Injection
  • Injection
Used for
AxironAndrodermAndrogelFortestaTestimDelatestrylDepo-TestosteroneAveed
  • Low Testosterone
  • Low Testosterone
  • Low Testosterone
  • Low Testosterone
  • Low Testosterone
  • Low Testosterone
  • Low Testosterone
  • Low Testosterone
Risk factors for serious side effects
AxironAndrodermAndrogelFortestaTestimDelatestrylDepo-TestosteroneAveed
    Coming soon.
      Coming soon.
        Coming soon.
          Coming soon.
            Coming soon.
            • Male
            • Enlarged prostate (benign prostatic hypertrophy)
            • Taking high doses of Delatestryl (Testosterone Enanthate Injection)
            • Heart, liver or kidney disease
            Detailed Delatestryl (testosterone enanthate injection) risks & warnings »
            • Male
            • Enlarged prostate (benign prostatic hypertrophy)
            • Taking high doses of Depo-Testosterone (Testosterone Cypionate Injection)
            • Heart, liver or kidney disease
            Detailed Depo-Testosterone (testosterone cypionate injection) risks & warnings »
            • Male
            • Enlarged prostate (benign prostatic hypertrophy)
            • Taking high doses of Aveed (Testosterone Undecanoate Injection)
            • Heart, liver or kidney disease
            Detailed Aveed (testosterone undecanoate injection) risks & warnings »
            Pregnancy

            Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

            Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

            Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

            Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

            Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

            Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

            Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

            Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

            Kidneys and liver
            AxironAndrodermAndrogelFortestaTestimDelatestrylDepo-TestosteroneAveed
            No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
            • There have been reports of people on Delatestryl (Testosterone Enanthate Injection) who have developed high levels of calcium in the blood, which can be bad for the kidneys. This can happen if you have cancer or if you are unable to move around. If you notice a metallic taste in your mouth, muscle or joint pain or a bad headache, talk to your doctor, since they may have to stop the medication.
            • There have been reports of people on Depo-Testosterone (Testosterone Cypionate Injection) who have developed high levels of calcium in the blood, which can be bad for the kidneys. This can happen if you are unable to move around or have cancer. If you notice a metallic taste in your mouth, muscle or joint pain or a bad headache, talk to your doctor, since they may have to stop the medication.
            • There have been reports of people on Aveed (Testosterone Undecanoate Injection) who have developed high levels of calcium in the blood, which can be bad for the kidneys. This can happen if you are unable to move around or if you have cancer. If you notice a metallic taste in your mouth, muscle or joint pain or a bad headache, talk to your doctor, since they may have to stop the medication.
            Pain
            AxironAndrodermAndrogelFortestaTestimDelatestrylDepo-TestosteroneAveed
            No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.
            • If you're on Delatestryl (Testosterone Enanthate Injection), and you notice pain in your abdomen, or if your skin or the whites of your eyes turn yellow, call your doctor immediately. This can be liver damage.
            No pain related info.
            • If you're on Aveed (Testosterone Undecanoate Injection), and you notice pain in your abdomen, or if your skin or the whites of your eyes turn yellow, call your doctor immediately. This can be liver damage.
            Upsides and benefits
            AxironAndrodermAndrogelFortestaTestimDelatestrylDepo-TestosteroneAveed
            • You're less likely with this formulation to transfer testosterone topical solution to another person since this is applied to the armpits -- unlike some other forms of topical testosterone.
            • You can use your regular deodorant or antiperspirant, but just make sure to apply that first before using testosterone topical solution.
            • The testosterone patch doesn't have to be removed when you're having sex or if you're showering or bathing.
            • The testosterone patch prevents other people around you from coming in contact with testosterone, unlike other topical forms such as gels.
            • The testosterone patch only has to be placed once each night.
            • You put it on like a lotion, so it's very easy to apply.
            • Available in generic, so it's cheaper than some alternatives.
            • You apply it to your thighs like a lotion.
            • Putting testosterone gel on your thights makes it less likely you'll transfer the medication to other people around you, compared to some other kinds of topical testosterone.
            • You apply it to your shoulders and upper arms like a lotion, so it's easy to use.
            • Available in individual daily doses, so it's more convenient than some alternatives.
            • A first-choice treatment for low testosterone in men and delayed puberty in boys.
            • Available in generic.
            • Only has to be given once every 2 to 4 weeks.
            • The shot can be done at home.
            • A first-choice treatment for low testosterone in men and delayed puberty in boys.
            • Available in generic.
            • Only has to be given once every 2 to 4 weeks.
            • The shot can be done at home.
            • A first-choice treatment for low testosterone in men.
            • The first two shots are spaced out by a month, then each shot after that is given every 10 weeks.
            • Your doctor will give you the shot.
            Downsides and risks
            AxironAndrodermAndrogelFortestaTestimDelatestrylDepo-TestosteroneAveed
            • Only available as brand name.
            • You have to wait at least 2 hours after applying testosterone topical solution before you can swim or bathe, otherwise your body won't absorb the entire amount.
            • Not available in generic.
            • You have to be careful to rotate the testosterone patch to a different part of your body each night.
            • Can cause skin irritation.
            • Has to be removed before you have an MRI.
            • The patch can become loose if you do heavy exercise or sweat a lot.
            • You have to make sure that you cover the area where you place testosterone gel after it's dry, otherwise it can rub off on people.
            • You have to wait at least 2 hours before you shower or swim after putting on Testosterone gel, otherwise your body won't absorb the entire amount.
            • Not available in generic form, so it can be more expensive.
            • You have to wait at least 2 hours after applying testosterone gel before you can swim or bathe, otherwise your body won't absorb the full amount of the medication.
            • Not available in generic form, so it can be more expensive.
            • You have to let the skin dry after you've put on testosterone gel, and you have to wear clothes over the area to prevent the medication from spreading onto other people.
            • You have to wait at least 2 hours after applying testosterone gel before you can swim or bathe, otherwise your body won't absorb the full amount of the medication.
            • Only available as a shot.
            • Has to be given by someone else since it has to be injected into your buttocks.
            • Not a first-choice treatment for breast cancers that respond to testosterone.
            • Only available as a shot.
            • Has to be given by someone else since it has to be injected into your buttocks.
            • Your doctor has to give you this shot. You can't do it at home.
            • Your doctor has to watch you for 30 minutes after your shot to make sure you don't have problems breathing or get a severe allergic reaction.
            • Your doctor has to file paperwork each time you get the shot because of the risks involved.
            • Not available as a generic, so it can be expensive.
            Tips from our pharmacists for people taking the medication
            AxironAndrodermAndrogelFortestaTestimDelatestrylDepo-TestosteroneAveed
            • Prime testosterone topical solution first by pumping 3 times before you use a new bottle.
            • If you use deodorant or antiperspirant, apply that first before using testosterone topical solution.
            • Don't swim or bathe for at least 2 hours after you put on testosterone topical solution so that it has time to absorb.
            • Cover the area with clothing as soon as it's dry so you don't spread it to other people.
            • If you think you'll have skin-to-skin contact at the area where you've placed testosterone topical solution, wash that area with soap and water then dry.
            • Don't use testosterone topical solution anywhere besides your armpits.
            • Place the testosterone patch on a clean, dry area of your skin each night. Don't put it on your scrotum or a bony part of your body.
            • Change the area where you place the testosterone patch every night, and wait at least 7 days before you put in on the same site again.
            • Make sure the patch is attached to your skin, especially along the edges. If it loosens, smooth the edges and then the center of the patch with your finger to make sure it's attached completely.
            • If the patch falls off before noon, apply another patch. If it falls off after that, don't apply another patch until your regular time at night. Don't use tape to keep the patch attached.
            • Don't bathe or swim for at least 3 hours after you put a new patch on. Also, heavy exercise or lots of sweating can make your patch fall off.
            • How to put it on: Don't put testosterone gel anywhere else except where you're taught by the doctor or pharmacist, usually the shoulders and upper arms. Don't put it around your genitals. Wash your hands with soap and water and dry them afterward. Cover the area with clothing as soon as it's dry so you don't spread it to other people.
            • Don't bathe or swim for at least 2 hours after you've put on testosterone gel so that it has time to absorb.
            • If you think you'll have skin-to-skin contact with someone else at the area where you've placed testosterone gel, wash that area with soap and water and dry. If someone else touches the area before you've washed it off, have them wash their skin with soap and water as soon as they can.
            • Prime testosterone gel first by pumping 8 times before you use a new bottle.
            • Don't swim or bathe for at least 2 hours after you apply testosterone gel.
            • Wash your hands with soap and water, and cover the area with clothing as soon as the gel is dry so you don't spread it to other people.
            • If you think you'll have skin-to-skin contact at the area where you've placed testosterone gel, wash that area with soap and water then dry.
            • Don't use testosterone gel anywhere besides your front and inner thighs.
            • Use the entire contents of one tube each day and apply to your shoulders and upper arms. Don't put it anywhere else.
            • Don't swim or bathe for at least 2 hours after you apply testosterone gel.
            • Cover the area with clothing as soon as it's dry so you don't spread it to other people, and wash your hands with soap and water.
            • If you think you'll have skin-to-skin contact at the area where you've placed testosterone gel, wash that area with soap and water then dry.
            • Your doctor will show you how to inject this correctly.
            • Can cause nausea, vomiting and headache.
            • Can cause increased acne and changes in sex drive.
            • Keep this medication locked up and away from children since it's a controlled substance.
            • Your doctor will show you how to inject this correctly.
            • Can cause nausea, vomiting and headache.
            • Can cause increased acne and changes in sex drive.
            • Keep this medication locked up and away from children since it's a controlled substance.
            • This medication is only available through a special screening program because of the side effects.
            • Your doctor will watch you for 30 minutes after each injection to make sure you don't have problems breathing or get an allergic reaction.
            • Can cause nausea, vomiting and headache.
            • Can cause increased acne and changes in sex drive.
            Learn more
            More about AxironSide effectsReviews & ratingsAlternativesFDA package insert
            Have you used Axiron (testosterone topical solution)?
            Worth itNot sureNot worth it
            More about AndrodermSide effectsReviews & ratingsFDA package insert
            Have you used Androderm (testosterone patch)?
            Worth itNot sureNot worth it
            More about AndrogelSide effectsReviews & ratingsFDA package insert
            Have you used Androgel (testosterone gel)?
            Worth itNot sureNot worth it
            More about FortestaSide effectsReviews & ratingsFDA package insert
            Have you used Fortesta (testosterone gel)?
            Worth itNot sureNot worth it
            More about TestimSide effectsReviews & ratingsFDA package insert
            Have you used Testim (testosterone gel)?
            Worth itNot sureNot worth it
            More about DelatestrylSide effectsReviews & ratingsFDA package insert
            Have you used Delatestryl (testosterone enanthate injection)?
            Worth itNot sureNot worth it
            More about Depo-TestosteroneSide effectsReviews & ratingsFDA package insert
            Have you used Depo-Testosterone (testosterone cypionate injection)?
            Worth itNot sureNot worth it
            More about AveedSide effectsReviews & ratingsFDA package insert
            Have you used Aveed (testosterone undecanoate injection)?
            Worth itNot sureNot worth it