Prescription onlyLower-cost generic available



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Lowers blood pressure.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Captopril is a good blood pressure-lowering medicine that protects kidney function, but you have to take it on an empty stomach.

Worth itNot sureNope
Worked WellSomewhatDidn't work
No hassleSomewhatHuge hassle
Worth it
Men: 33%
Women: 33%
Works well
Men: 25%
Women: 25%
It's a hassle
Men: 26%
Women: 26%
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Compared to other ACE inhibitors, less flexible on when and how you take it. Captopril needs to be taken multiple times a day on an empty stomach.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.

Save on your next Capoten (Captopril) prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.

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Side effects for Capoten (Captopril)

From clinical trials of Captopril / Any condition ( 7000)

  • RashRash7% for Captopril vs.0% for placebo
  • FlushingFlushing5% for Captopril vs.0% for placebo
  • Abnormal sense of tasteAbnormal sense of taste4% for Captopril vs.0% for placebo
  • ItchingItching2% for Captopril vs.0% for placebo
  • CoughCough2% for Captopril vs.0% for placebo
  • ProteinuriaProteinuria1% for Captopril vs.0% for placebo

Manufacturers don’t say how common these side effects are

  • Abdominal pain
  • Abnormally fast heart beat
  • Abnormally large breasts in males
  • Blurred vision
  • Bronchospasm
  • Bullous pemphigus
  • Canker sore
  • Cerebrovascular accident/insufficiency
  • Chest pain
  • Cholestasis
  • Confusion
  • Constipation
  • Deep skin swelling
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Eosinophilic pneumonitis
  • Erythema multiforme
  • Exfoliative dermatitis
  • Fainting
  • Fatigue
  • Feeling unwell
  • Gastric irritation
  • Hair loss or baldness
  • Headache
  • Heart pounding or racing sensation
  • Impotence
  • Indigestion
  • Inflammation inside the nose
  • Lack of muscle coordination
  • Liver inflammation
  • Loss of appetite
  • Low blood cell count
  • Low blood pressure
  • Low mood disorder
  • Low red blood cells
  • Muscle pain
  • Muscle weakness
  • Nausea
  • Nervousness
  • Neutropenia/agranulocytosis
  • Pancreatitis
  • Peptic ulcer
  • Positional low blood pressure
  • Rhythm disturbances
  • Serious allergic reaction
  • Shortness of breath
  • Sleep difficulty
  • Stopped heart and circulation
  • Symptomatic hyponatremia
  • Thrombocytopenia
  • Tingling sensation
  • Tongue inflammation
  • Vomiting
  • Yellow skin or eyes

Pharmacist tips

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  • Take 1 hour before or 2 hours after eating.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or change in taste sensation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.

Risks and Warnings for Capoten (Captopril)

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    • Higher risk if:
    • Women of childbearing age

    Capoten (Captopril) can cause birth defects or death to a fetus. If you are pregnant or considering having a baby, talk to your doctor about alternative medicines.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Capoten (Captopril)

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The FDA category for this medication is D. It is advised that you: Weigh risks vs. benefits
Kidneys & liver
  • Upsides and downsides from our pharmacists
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Tips from our pharmacists
  • Requires routine blood tests to check kidney function.