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Capoten Alternatives

(Captopril)

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Compare Capoten (Captopril) to alternatives

These medications are comparable to Capoten (Captopril) or used for similar purposes.

Capoten
(Captopril)

Zestril
(Lisinopril)

Lotensin
(Benazepril)

Vasotec
(Enalapril)

Cozaar
(Losartan)

Norvasc
(Amlodipine)

Microzide
(Hydrochlorothiazide )

Lopressor
(Metoprolol Tartrate)

Toprol Xl
(Metoprolol Succinate)

Lowers blood pressure. Captopril is a good blood pressure-lowering medicine that protects kidney function, but you have to take it on an empty stomach.Lowers blood pressure. Zestril (Lisinopril) is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Benazepril is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Enalapril is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.Lowers blood pressure. Norvasc (Amlodipine) works well to lower blood pressure and prevent chest pain. You can't miss doses, and you might get persistent swelling.Lowers blood pressure. Removes extra water from your body. Microzide (Hydrochlorothiazide (Hctz)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Lowers blood pressure and controls heart rate. Lopressor (Metoprolol Tartrate) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.Lowers blood pressure and controls heart rate. Toprol Xl (Metoprolol Succinate) is good for controlling chest pain and treating heart failure and heart attack. You can't miss doses.
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Reviews & ratings
Button Group. All currently active
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3.8190476190476192Captopril
Reviews for Capoten (Captopril)
33%
of people say Capoten (Captopril) is worth it
25%
say it works well
26%
say it's a big hassle
Reviews for Zestril (Lisinopril)
61%
+28% vs. Capoten (Captopril)
51%
+26% vs. Capoten (Captopril)
13%
+13% vs. Capoten (Captopril)
Reviews for Lotensin (Benazepril)
63%
+30% vs. Capoten (Captopril)
63%
+38% vs. Capoten (Captopril)
21%
+5% vs. Capoten (Captopril)
Reviews for Vasotec (Enalapril)
44%
+11% vs. Capoten (Captopril)
40%
+15% vs. Capoten (Captopril)
21%
+5% vs. Capoten (Captopril)
Reviews for Cozaar (Losartan)
57%
+24% vs. Capoten (Captopril)
47%
+22% vs. Capoten (Captopril)
16%
+10% vs. Capoten (Captopril)
Reviews for Norvasc (Amlodipine)
59%
+26% vs. Capoten (Captopril)
50%
+25% vs. Capoten (Captopril)
14%
+12% vs. Capoten (Captopril)
Reviews for Microzide (Hydrochlorothiazide (Hctz))
47%
+14% vs. Capoten (Captopril)
31%
+6% vs. Capoten (Captopril)
15%
+11% vs. Capoten (Captopril)
Reviews for Lopressor (Metoprolol Tartrate)
61%
+28% vs. Capoten (Captopril)
46%
+21% vs. Capoten (Captopril)
15%
+11% vs. Capoten (Captopril)
Reviews for Toprol Xl (Metoprolol Succinate)
60%
+27% vs. Capoten (Captopril)
55%
+30% vs. Capoten (Captopril)
13%
+13% vs. Capoten (Captopril)
Side effects
CaptoprilLisinoprilBenazeprilEnalaprilLosartanNorvascHydrochlorothiazideLopressorToprol XL

The Captopril FDA package insert doesn’t have numbers about how common side effects are.

More about Captopril side effects »
  • Dizziness 7%
  • Headache 4%
  • Cough 3%
  • Diarrhea 2%
  • Chest pain 2%
  • Fatigue 2%
  • Upper respiratory infection 1%
More Lisinopril side effects »
  • Dizziness 2%
  • Headache 2%
More Benazepril side effects »
  • Diarrhea 1%
  • Vertigo 1%
More Enalapril side effects »
  • Urinary tract infection 6%
  • Diarrhea 5%
  • Low blood sugar 4%
  • Low blood pressure 4%
  • Muscle weakness/fatiguea/fatigue 4%
  • Hyperkalemia 4%
  • Chest pain 4%
  • Low red blood cells 3%
  • Muscular weakness 3%
  • Orthostatic hypotension 3%
More Losartan side effects »
  • Swelling due to excess fluid 10%
  • Fatigue 2%
  • Nausea 1%
  • Dizziness 1%
More Norvasc side effects »

The Hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about Hydrochlorothiazide side effects »
  • Abnormally slow heartbeat 9%
  • Low blood pressure 4%
  • First-degree heart block 3%
More Lopressor side effects »
  • Abnormally slow heartbeat 9%
  • Low blood pressure 4%
  • Heart block 3%
More Toprol XL side effects »
How it works
CaptoprilLisinoprilBenazeprilEnalaprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
Captopril is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Zestril (Lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Benazepril is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Enalapril is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Cozaar (Losartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Norvasc (Amlodipine) is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Microzide (Hydrochlorothiazide (Hctz)) is a thiazide diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Lopressor (Metoprolol Tartrate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Toprol Xl (Metoprolol Succinate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
CaptoprilLisinoprilBenazeprilEnalaprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
Angiotensin receptor blocker
Prescription only
Antihypertensive
Calcium channel blocker
Prescription only
Antihypertensive
Diuretic
Prescription only
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Beta blocker
Prescription only
Available as
CaptoprilLisinoprilBenazeprilEnalaprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
  • Pill
  • Pill
  • Pill
  • Pill
  • Liquid
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
  • Extended release
Used for (click to learn more)
CaptoprilLisinoprilBenazeprilEnalaprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
Risk factors for serious side effects
CaptoprilLisinoprilBenazeprilEnalaprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
  • Women of childbearing age
    • African descent
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
    Detailed Capoten (Captopril) risks & warnings »
    Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.
    Pregnancy category
    CaptoprilLisinoprilBenazeprilEnalaprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    BFDA pregnancy category (Probably safe)

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.No specific food-related info.
    • Metoprolol tartrate is the immediate release version of Toprol XL. You have to take Metoprolol tartrate with food for it to work best. (On the other hand, you can take Toprol XL any time.)
    • Take it with food.
    No specific food-related info.
    Kidneys and liver
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Requires routine blood tests to check kidney function.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Requires routine blood tests to check kidney function.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Requires routine blood tests to check kidney function.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Requires routine blood tests to check kidney function.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Requires routine blood tests to check kidney function.
    No specific kidneys and liver-related info.
    • Doesn't work well in people with severe kidney problems.
    • Requires routine blood tests to check kidney function.
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    CaptoprilLisinoprilBenazeprilEnalaprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • The only ACE inhibitor that doctors can give through an IV if that's needed.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • Calcium channel blockers work especially well for African Americans to lower blood pressure.
    • Prevents heart-related chest pain (angina) if you take it regularly.
    • Each dose lasts longer than other calcium channel blockers, which keeps blood pressure consistent without big ups and downs.
    • Particularly good at lowering systolic blood pressure (the top number), so it's a good option for older people who can commonly get high blood pressure only in the top number.
    • Works well to get rid of extra fluids in your body through urination.
    • A first-choice blood pressure treatment for many people. Works especially well for African Americans.
    • Good option if you have both high blood pressure and heart failure.
    • Raises calcium levels in the body, so it can be good for people with osteoporosis to slow down bone loss and even help with new bone formation.
    • Most people have very few side effects.
    • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
    • A first-choice treatment for heart failure. May prevent long-term heart damage.
    • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
    • Toprol XL is the extended release version of Lopressor.
    • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
    • A first-choice treatment for heart failure. May prevent long-term heart damage.
    • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
    Downsides and risks
    CaptoprilLisinoprilBenazeprilEnalaprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
    • Compared to other ACE inhibitors, less flexible on when and how you take it. Captopril needs to be taken multiple times a day on an empty stomach.
    • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Not safe to use if you're pregnant.
    • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Not safe to use if you're pregnant.
    • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Not safe to use if you're pregnant.
    • Compared to other ACE inhibitors, less flexible on when you take it. Enalapril needs to be taken multiple times a day on an empty stomach.
    • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Not safe to use if you're pregnant.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Not safe to use if you're pregnant.
    • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
    • Women are more likely to have side effects (especially swelling) from Amlodipine than men.
    • Some people might experience flushing with this medication.
    • You can't miss doses. Stopping Amlodipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • If you have severe heart disease, using Amlodipine might increase your risk of chest pain or heart attack during the time right after starting the medication or raising the dosage.
    • Might not be a good choice if you have liver disease.
    • Makes you urinate more often.
    • Doesn't work well in people with severe kidney problems.
    • Metoprolol tartrate is the immediate release version of Toprol XL. You have to take Metoprolol tartrate with food for it to work best. (On the other hand, you can take Toprol XL any time.)
    • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
    • You can't miss doses. Stopping Metoprolol tartrate suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
    • Can hide symptoms of low blood sugar if you're diabetic.
    • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease.
    • You can't miss doses. Stopping Toprol XL suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
    • Can hide symptoms of low blood sugar if you're diabetic.
    Tips from our pharmacists for people taking the medication
    CaptoprilLisinoprilBenazeprilEnalaprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
    • Take 1 hour before or 2 hours after eating.
    • Tell your doctor about any dizziness, fatigue, cough, or change in taste sensation that doesn't go away.
    • Don't take it if you're pregnant.
    • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
    • Don't take it if you're pregnant.
    • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
    • Don't take it if you're pregnant.
    • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
    • Don't take it if you're pregnant.
    • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
    • Don't take it if you're pregnant.
    • Interacts with the cholesterol medicine Simvastatin.
    • Can cause ankle or foot swelling.
    • Can cause gum overgrowth. Ask your dentist to check for this side effect.
    • Starts working in about 2 hours.
    • Makes you urinate more often, so avoid taking it at bedtime.
    • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
    • Take it with food.
    • This is the immediate release version. It also comes as an extended release form: Toprol XL (metoprolol succinate).
    • Can cause fatigue and headache.
    • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
    • Don't stop taking this medicine suddenly.
    • Extended release version. Also comes in immediate release called Lopressor (metoprolol tartrate).
    • Can cause fatigue and headache.
    • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
    • Don't stop taking this medicine suddenly.
    Learn more
    More about CaptoprilSide effectsReviews & ratingsAlternativesFDA package insert
    More about LisinoprilSide effectsReviews & ratingsFDA package insert
    More about BenazeprilSide effectsReviews & ratingsFDA package insert
    More about EnalaprilSide effectsReviews & ratingsFDA package insert
    More about LosartanSide effectsReviews & ratingsFDA package insert
    More about NorvascSide effectsReviews & ratingsFDA package insert
    More about HydrochlorothiazideSide effectsReviews & ratingsFDA package insert
    More about LopressorSide effectsReviews & ratingsFDA package insert
    More about Toprol XLSide effectsReviews & ratingsFDA package insert