Prescription onlyLower-cost generic availableClass: neuro/psych

Sinemet 

(carbidopa / levodopa)

Prescription onlyLower-cost generic availableClass: neuro/psych
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Treats Parkinson's disease.

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Our bottom line

Sinemet (carbidopa / levodopa) is the first choice treatment for Parkinson's disease.

Price and discounts
Best available price for 90 (25mg/100mg) tablets of carbidopa / levodopa

Upsides

  • Sinemet (carbidopa / levodopa) is widely available as a regular pill, a quick dissolving pill or a liquid taken through a feeding tube.
  • Sinemet (carbidopa / levodopa) is available in generic.

Downsides

  • Can make you very sleepy.
  • Can stain your saliva, sweat and urine a dark color.
  • Will lose its effect over time as your disease progresses.
  • May need to be taken several times during day to control symptoms of Parkinson's disease
  • May cause unusual cravings in some people.
How it works

Sinemet (carbidopa / levodopa) is a combination of carbidopa and levodopa. Carbidopa prevents breakdown of levodopa allowing it to enter the brain and relieve symptoms of Parkinson's disease.

What to expect when you take Sinemet (carbidopa / levodopa) for Parkinson's disease

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Side effect rates for Sinemet (carbidopa / levodopa)

Risks and Warnings for Sinemet (carbidopa / levodopa)

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    • Higher risk if:
    • Taking other medicines for Parkinson's

    Sinemet (carbidopa / levodopa) can make you very sleepy. This is more likely to happen if you are also taking other medicines for Parkinson's disease. Don't drive or do anything that requires your full concentration until you know how Sinemet (carbidopa / levodopa) affects you.

Common concerns from people taking Sinemet (carbidopa / levodopa)

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Sleep
  • Can make you very sleepy.
  • Can make you very sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.