Prescription onlyLower-cost generic availableClass: neuro/psych

Sinemet CR 

(carbidopa / levodopa extended release)

Prescription onlyLower-cost generic availableClass: neuro/psych
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Treats Parkinson's disease.

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Our bottom line

Sinemet CR (carbidopa / levodopa extended release) is the first choice treatment for Parkinson's disease.

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Upsides

  • Sinemet CR (carbidopa / levodopa extended release) is released over a long period of time in your body and can allow you to take fewer pills less frequently.

Downsides

  • Sinemet CR (carbidopa / levodopa extended release) can make you very sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
  • Your saliva, sweat and urine may have dark color and stain your clothing while taking Sinemet CR (carbidopa / levodopa extended release).
  • Sinemet CR (carbidopa / levodopa extended release) will lose its effect over time. If you notice it wearing off sooner than you'd like, talk to your doctor.
  • Sinemet CR (carbidopa / levodopa extended release) may cause unusual cravings in some people.
How it works

Sinemet CR (carbidopa / levodopa extended release) is a combination of carbidopa and levodopa that is released in your body over time. Carbidopa prevents breakdown of levodopa so that levodopa can then, enter the brain and relieve symptoms of Parkinson's disease.

What to expect when you take Sinemet CR (carbidopa / levodopa extended release) for Parkinson's disease

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Side effect rates for Sinemet CR (carbidopa / levodopa extended release)

491 From clinical trials of carbidopa / levodopa extended release / Parkinson's disease
  • Difficulty controlling movements
  • Nausea
  • Hallucinations
  • Confusion
  • Dizziness
  • Low mood disorder
  • Urinary tract infection
  • Back pain
  • Unusual dreams
  • Muscle spasms

Risks and Warnings for Sinemet CR (carbidopa / levodopa extended release)

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    • Higher risk if:
    • Taking other medicines for Parkinson's

    Sinemet CR (carbidopa / levodopa extended release) can make you sleepy or fall asleep suddenly without warning. Don't drive or do anything that requires your full concentration until you know how Sinemet CR (carbidopa / levodopa extended release) affects you. You're more at risk if you're taking other medicines for Parkinson's. Talk to your doctor if this bothers you.

Common concerns from people taking Sinemet CR (carbidopa / levodopa extended release)

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