Catapres Alternatives

(Clonidine)

Alternatives

Compare Catapres (Clonidine) to alternatives

These medications are comparable to Catapres (Clonidine) or used for similar purposes.

Catapres
(Clonidine)

Zestril
(lisinopril)

losartan

Norvasc
(Amlodipine)

Toprol XL
(metoprolol succinate)

Tenormin
(atenolol)

Coreg
(Carvedilol)

Microzide
(hydrochlorothiazide )

Lowers blood pressure. Catapres (Clonidine) is a good addition if you need more than one medicine to control your blood pressure, but it has a lot of side effects. You can't miss doses.Lowers blood pressure. Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.Lowers blood pressure. Norvasc (Amlodipine) works well to lower blood pressure and prevent chest pain. You can't miss doses, and you might get persistent swelling.Lowers blood pressure and controls heart rate. Toprol XL (metoprolol succinate) is good for controlling chest pain, treating heart failure, and heart attack. It has the added benefit of being taken once a day.Lowers blood pressure and controls heart rate. Tenormin (atenolol) is good for controlling chest pain and treating a heart attack. It has fewer side effects than other beta blockers. You need to take it on an empty stomach and you can't skip doses.Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.Removes water from the body, which lowers blood pressure. Microzide (hydrochlorothiazide (HCTZ)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.27Catapres
Reviews for Catapres
42%
of people (All ages) say Catapres is worth it
33%
say it works well
35%
say it's a big hassle
Have you used Catapres (Clonidine)?
Worth itNot sureNot worth it
Reviews for Lisinopril
61%
-19% worse vs. Catapres
51%
-18% worse vs. Catapres
14%
-21% worse vs. Catapres
687 reviews
Have you used Zestril (lisinopril)?
Worth itNot sureNot worth it
Reviews for Losartan
57%
-15% worse vs. Catapres
48%
-15% worse vs. Catapres
16%
-19% worse vs. Catapres
535 reviews
Have you used Cozaar (Losartan)?
Worth itNot sureNot worth it
Reviews for Norvasc
58%
-16% worse vs. Catapres
50%
-17% worse vs. Catapres
15%
-20% worse vs. Catapres
443 reviews
Have you used Norvasc (Amlodipine)?
Worth itNot sureNot worth it
Reviews for Toprol XL
60%
-18% worse vs. Catapres
54%
-21% worse vs. Catapres
13%
-22% worse vs. Catapres
164 reviews
Have you used Toprol XL (metoprolol succinate)?
Worth itNot sureNot worth it
Reviews for Atenolol
58%
-16% worse vs. Catapres
48%
-15% worse vs. Catapres
16%
-19% worse vs. Catapres
457 reviews
Have you used Tenormin (atenolol)?
Worth itNot sureNot worth it
Reviews for Coreg
53%
-11% worse vs. Catapres
46%
-13% worse vs. Catapres
18%
-17% worse vs. Catapres
406 reviews
Have you used Coreg (Carvedilol)?
Worth itNot sureNot worth it
Reviews for hydrochlorothiazide
47%
-5% worse vs. Catapres
31%
+2% better vs. Catapres
16%
-19% worse vs. Catapres
139 reviews
Have you used Microzide (hydrochlorothiazide (HCTZ))?
Worth itNot sureNot worth it
Side effects
CatapresLisinoprilLosartanNorvascToprol XLAtenololCoreghydrochlorothiazide
  • Insomnia 2%
  • Dizziness 2%
  • Impotence/sexual dysfunction 2%
  • Dry throat 2%
  • Lethargy 3%
  • Sedation 3%
  • Edema 3%
  • Excoriation 3%
  • Burning 3%
  • Headache 5%
More Catapres side effects »
  • Cough 3%
  • Headache 4%
  • Dizziness 4%
  • Chest pain 2%
  • Low blood pressure 4%
  • High potassium 6%
  • Fainting 7%
  • Kidney damage 10%
More Lisinopril side effects »
  • Back pain 1%
  • Nasal congestion 1%
  • Dizziness 1%
  • Upper respiratory infection 1%
  • Diabetic neuropathy 1%
  • Dyspepsia 1%
  • Fever 1%
  • Orthostatic hypotension 3%
  • Trauma 1%
  • Weight gain 1%
More Losartan side effects »
  • Edema 2%
  • Dizziness 1%
  • Flushing 3%
  • Palpitation 5%
  • Abdominal pain 2%
  • Nausea 1%
  • Fatigue 2%
  • Somnolence 2%
  • Palpitations 3%
More Norvasc side effects »
  • Shortness of breath 3%
  • Slower heartbeat 3%
  • Depression 5%
  • Skin rash and itching 5%
  • Diarrhea 5%
  • Tiredness 10%
  • Dizziness 10%
  • Dizziness/balance problems 1%
More Toprol XL side effects »
  • Feeling off balance 2%
  • Drowsiness 2%
  • Slower heartbeat 3%
  • Leg Pain 2%
  • Light-headedness 3%
  • Decreased energy 3%
  • Vivid dreams 2%
  • Diarrhea 1%
  • Nausea 2%
More Atenolol side effects »
  • Edema peripheral 1%
  • Edema dependent 2%
  • Hypercholesterolemia 1%
  • Digoxin level increased 1%
  • Edema generalized 2%
  • Vision abnormal 3%
  • Vomiting 2%
More Coreg side effects »

The hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about hydrochlorothiazide side effects »
How it works
CatapresLisinoprilLosartanNorvascToprol XLAtenololCoreghydrochlorothiazide
Catapres (Clonidine) is an alpha-2 agonist. It works in the brain to tell your blood vessels to relax, and it lowers the activity of certain stress hormones. This lowers blood pressure.Zestril (lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Cozaar (Losartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Norvasc (Amlodipine) is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Toprol XL (metoprolol succinate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Tenormin (atenolol) is a selective beta blocker that works specifically on the heart by slowing down the heart and making the heart pump better.Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Microzide (hydrochlorothiazide (HCTZ)) is a thiazide diuretic (water pill) that makes you urinate more. It works in the kidneys to remove extra water and certain electrolytes, while lowering blood pressure and reducing swelling.
Type of medication
CatapresLisinoprilLosartanNorvascToprol XLAtenololCoreghydrochlorothiazide
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
CatapresLisinoprilLosartanNorvascToprol XLAtenololCoreghydrochlorothiazide
  • Pill
  • Extended release
  • Patch
  • Pill
  • Liquid
  • Pill
  • Pill
  • Extended release
  • Pill
  • Pill
  • Extended release
  • Pill
Used for
CatapresLisinoprilLosartanNorvascToprol XLAtenololCoreghydrochlorothiazide
Risk factors for serious side effects
CatapresLisinoprilLosartanNorvascToprol XLAtenololCoreghydrochlorothiazide
  • Sudden discontinuation of medicine
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 years or older
  • Using other medicine(s) that slows the heart
Detailed Catapres (Clonidine) risks & warnings »
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicines that increase potassium
  • Use of salt substitutes
Detailed Zestril (lisinopril) risks & warnings »
  • Women of childbearing age
  • Concurrent liver disease
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed Cozaar (Losartan) risks & warnings »
  • Age 65 years or older
  • History of heart problems
  • Liver disease
  • History of blood vessel disease
  • History of heart failure
Detailed Norvasc (Amlodipine) risks & warnings »
  • Sudden discontinuation of medicine
  • Coronary artery disease
  • Diabetes
  • Hyperthyroidsim
  • Heart failure
Detailed Toprol XL (metoprolol succinate) risks & warnings »
  • Suddenly stopping Tenormin (atenolol)
  • Taking calcium channel blockers
  • Major surgery requiring anesthesia
  • Diabetes
  • Taking clonidine
Detailed Tenormin (atenolol) risks & warnings »
  • Abrupt discontinuation of Coreg (Carvedilol)
  • Congestive heart failure
  • Increasing the dose of Coreg (Carvedilol)
  • Diabetes
  • Major surgery requiring anesthesia
Detailed Coreg (Carvedilol) risks & warnings »
  • Current electrolyte imbalance
  • Lower kidney function
  • Dehydration
  • History of sulfa allergies
  • History of gout
Detailed Microzide (hydrochlorothiazide (HCTZ)) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Interactions
CatapresLisinoprilLosartanNorvascToprol XLAtenololCoreghydrochlorothiazide
No interactions related info.No interactions related info.No interactions related info.
  • Interacts with the cholesterol medicine Simvastatin.
No interactions related info.No interactions related info.No interactions related info.No interactions related info.
Food
CatapresLisinoprilLosartanNorvascToprol XLAtenololCoreghydrochlorothiazide
No food related info.No food related info.No food related info.No food related info.No food related info.No food related info.
  • Take it with food.
  • You have to take Carvedilol with food.
No food related info.
Kidneys and liver
CatapresLisinoprilLosartanNorvascToprol XLAtenololCoreghydrochlorothiazide
No kidneys and liver related info.
  • You'll need to have blood tests done to check your kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Your body uses your liver to break down Norvasc (Amlodipine) and remove it from your blood. If you have liver disease you may not be able to remove Norvasc (Amlodipine) as quickly from your blood as someone with a healthy liver. You should increase the dose of Norvasc (Amlodipine) slowly and watch closely for how it is working in your body. Increasing the dose slowly will lower your chances of having side effects.
  • Might not be a good choice if you have liver disease.
No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
  • Requires routine blood tests to check kidney function.
Pain
CatapresLisinoprilLosartanNorvascToprol XLAtenololCoreghydrochlorothiazide
No pain related info.No pain related info.No pain related info.
  • Worsening heart pain or increased risk of heart attack is possible when you first start taking Norvasc (Amlodipine). This can also happen after you increase the dose of Norvasc (Amlodipine). Notify your doctor immediately if you experience any heart pain, radiating jaw pain, crushing chest pain, or persistent racing heartbeat.
No pain related info.No pain related info.No pain related info.No pain related info.
Sleep
CatapresLisinoprilLosartanNorvascToprol XLAtenololCoreghydrochlorothiazide
  • Can cause drowsiness, headache, dizziness, and dry mouth.
No sleep related info.No sleep related info.No sleep related info.No sleep related info.No sleep related info.No sleep related info.No sleep related info.
Upsides and benefits
CatapresLisinoprilLosartanNorvascToprol XLAtenololCoreghydrochlorothiazide
  • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
  • Available in a weekly patch for people that aren't good at taking medicine by mouth.
  • Works in the brain, so it can help treat some nervous system and psychiatric conditions.
  • Under the brand name Kapvay, it's used to treat ADHD in children and teenagers.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Very cheap drug, and comes available as a liquid for children over 6 years of age.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Each dose lasts longer than other calcium channel blockers, which keeps blood pressure consistent without big ups and downs.
  • Particularly good at lowering systolic blood pressure (the top number), so it's a good option for older people who can commonly get high blood pressure only in the top number.
  • A first-choice treatment to prevent chest pain (angina). It makes attacks less frequent and helps you be more active without having chest pain.
  • Toprol XL (metoprolol succinate) is a first-choice treatment for heart failure since it may prevent long-term heart damage.
  • It's also a first-choice for heart attack treatment since it lowers the risk of death during and after a heart attack.
  • Toprol XL (metoprolol succinate) is the extended release version of metoprolol tartrate and only needs to be taken once a day.
  • It's available as a generic and is relatively cheap.
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart attack recovery.
  • At lower doses, Tenormin (atenolol) has fewer side effects than other beta blockers because it targets the heart and not other parts of the body.
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure and heart attack.
  • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
  • Does a good job getting rid of extra fluids in your body by making you urinate more.
  • A first-choice blood pressure treatment. Works especially well for people of African descent.
  • Lowers the risk of heart attack and stroke.
  • Good option if you have high blood pressure and heart failure.
  • Most people have very few side effects from Microzide (hydrochlorothiazide (HCTZ)).
  • Can be good for patients with osteoporosis since it raises the body's level of calcium.
Downsides and risks
CatapresLisinoprilLosartanNorvascToprol XLAtenololCoreghydrochlorothiazide
  • Has a lot of side effects compared to other blood pressure-lowering medicine because it works in the brain.
  • The pill form can make some people sleepy, dizzy, and have dry mouth.
  • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Zestril (lisinopril) isn't safe to use if you're pregnant.
  • Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Amlodipine than men.
  • Some people might experience flushing with this medication.
  • You can't miss doses. Stopping Amlodipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • If you have severe heart disease, using Amlodipine might increase your risk of chest pain or heart attack during the time right after starting the medication or raising the dosage.
  • Might not be a good choice if you have liver disease.
  • Taking a beta blocker can make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some this may not go away.
  • It's not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease.
  • Toprol XL (metoprolol succinate) can hide symptoms of low blood sugar if you have diabetes.
  • You can't miss doses. Stopping Toprol XL (metoprolol succinate) suddenly can cause your blood pressure to go up quickly, which increases your risk of heart attack and stroke.
  • You need to take Tenormin (atenolol) on an empty stomach.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but it might not go away for others.
  • Not a first-choice treatment for high blood pressure unless you have heart disease. However, your doctor could add it to other medicines you're already if your blood pressure is still too high.
  • You can't miss or skip doses. If you stop Tenormin (atenolol) suddenly, it can cause your blood pressure to go up really quickly, raising your risk of heart attack and stroke.
  • Tenormin (atenolol) can hide symptoms of low blood sugar if you're diabetic.
  • You have to take Carvedilol with food.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Makes you urinate more often.
  • Microzide (hydrochlorothiazide (HCTZ)) doesn't work well in people with severe kidney problems.
  • It can increase the risk of gout attacks in people with poor kidney function or a history of gout.
  • People with a sulfa allergy may be allergic to Microzide (hydrochlorothiazide (HCTZ)).
Tips from our pharmacists for people taking the medication
CatapresLisinoprilLosartanNorvascToprol XLAtenololCoreghydrochlorothiazide
  • Usually taken together with other medicines for better blood pressure control.
  • Can cause drowsiness, headache, dizziness, and dry mouth.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • If side effects don't go away, talk to your doctor about alternatives.
  • The weekly patch form can have fewer side effects.
  • Don't stop taking this medicine suddenly.
  • Extended release tablet also used to treat ADHD.
  • Can cause dizziness the first few days you're taking it.
  • Check your blood pressure about 1 week after starting Zestril (lisinopril), and tell your doctor if it hasn't improved.
  • Let your doctor know about any dizziness, tiredness, cough, or throat irritation that doesn't go away.
  • You'll need to have blood tests done to check your kidney function.
  • Don't take Zestril (lisinopril) if you're pregnant.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Interacts with the cholesterol medicine Simvastatin.
  • Can cause ankle or foot swelling.
  • Can cause gum overgrowth. Ask your dentist to check for this side effect.
  • Toprol XL (metoprolol succinate) cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine and let your doctor know if it hasn't improved.
  • It can make you feel tired or give you headaches.
  • Can hide symptoms of low blood sugar, so be careful taking this if you have diabetes.
  • Don't stop taking this medicine suddenly.
  • This is the extended-release version, but it also comes in an immediate-release form, metoprolol tartrate.
  • Lowers bad cholesterol and triglycerides. Raises good cholesterol.
  • Avoid grapefruit and grapefruit juice while taking this medicine.
  • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
  • Tell your doctor if you notice dark urine or yellowing in your eyes or skin.
  • Take it with food.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause fatigue and erectile dysfunction.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly.
  • Microzide (hydrochlorothiazide (HCTZ)) starts working in about 2 hours.
  • It makes you urinate more often, so don't take it at bedtime.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any tiredness or muscle weakness that doesn't go away.
  • Requires routine blood tests to check kidney function.
Learn more
More about CatapresSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Catapres (Clonidine)?
Worth itNot sureNot worth it
More about LisinoprilSide effectsReviews & ratingsFDA package insert
Have you used Zestril (lisinopril)?
Worth itNot sureNot worth it
More about LosartanSide effectsReviews & ratingsFDA package insert
Have you used Cozaar (Losartan)?
Worth itNot sureNot worth it
More about NorvascSide effectsReviews & ratingsFDA package insert
Have you used Norvasc (Amlodipine)?
Worth itNot sureNot worth it
More about Toprol XLSide effectsReviews & ratingsFDA package insert
Have you used Toprol XL (metoprolol succinate)?
Worth itNot sureNot worth it
More about AtenololSide effectsReviews & ratingsFDA package insert
Have you used Tenormin (atenolol)?
Worth itNot sureNot worth it
More about CoregSide effectsReviews & ratingsFDA package insert
Have you used Coreg (Carvedilol)?
Worth itNot sureNot worth it
More about hydrochlorothiazideSide effectsReviews & ratingsFDA package insert
Have you used Microzide (hydrochlorothiazide (HCTZ))?
Worth itNot sureNot worth it