Prescription onlyLower-cost generic availableClass: Pain

Celebrex Alternatives

(celecoxib)

Prescription onlyLower-cost generic availableClass: Pain
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Compare Celebrex (celecoxib) to alternatives

These medications are comparable to Celebrex (celecoxib) or used for similar purposes.

Celebrex
(celecoxib)

Mobic
(meloxicam)

Lodine
(etodolac)

Aleve
(naproxen)

Relafen
(nabumetone)

Percocet
(oxycodone / acetaminophen)

Norco
(hydrocodone / acetaminophen)

Ultram
(tramadol)

Tylenol Regular Strength
(acetaminophen)

Ms Contin
(morphine sulfate)

Zorvolex
(diclofenac)

Advil
(ibuprofen)

Relieves pain and inflammation. Celebrex (Celecoxib) works well for treating pain and causes less upset stomach than other NSAIDs.Relieves pain and inflammation. Mobic (meloxicam) works well for pain and inflammation and you only take it once a day, but you need a prescription.Coming soon.Relieves pain, fever, and inflammation. Aleve (Naproxen) works well for mild to moderate pain and inflammation, and it lasts longer than other NSAIDs.Coming soon.Treats moderate to severe pain. Percocet (Oxycodone / Acetaminophen) is the strongest prescription combination pain medicine for as needed pain relief, but make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.Treats moderate to severe pain. Norco (Hydrocodone / Acetaminophen) is a good option to treat pain as needed when over-the-counter medicines can't control the symptoms, but must make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.Treats moderate to severe pain. Ultram (tramadol) works well for pain. Although it's a little weaker than other opioids, it can still be addictive.Relieves pain and fever. Tylenol Regular Strength (Acetaminophen) reduces fever and relieves pain well, but it doesn't lower inflammation and swelling.Treats severe pain. Ms Contin (Morphine Sulfate) provides good long-term pain control without the need to take medicine frequently, but watch out for constipation.Treats arthritis pain and swelling. Zorvolex (Diclofenac) is an okay medication used to treat pain and swelling caused by arthritis. However, because of the risk of heart attack, you should limit the amount you take.Relieves pain, fever, and swelling. Advil (ibuprofen) works well for treating fever, inflammation, and a variety of mild to moderate pain conditions, but it doesn't last as long as other NSAIDs.
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Reviews & ratings
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4.59Celebrex
Reviews for Celebrex (celecoxib)
57%
of people (All ages) say Celebrex (celecoxib) is worth it
38%
say it works well
14%
say it's a big hassle
550 reviews
Have you used Celebrex (celecoxib)?
Worth itNot sureNot worth it
Reviews for Mobic (meloxicam)
64%
+7% better vs. Celebrex (celecoxib)
54%
+16% better vs. Celebrex (celecoxib)
13%
+1% better vs. Celebrex (celecoxib)
141 reviews
Have you used Mobic (meloxicam)?
Worth itNot sureNot worth it
Reviews for Lodine (etodolac)
Not enough review data. Review it!
-27% worse vs. Celebrex (celecoxib)
Not enough review data. Review it!
-18% worse vs. Celebrex (celecoxib)
Not enough review data. Review it!
+4% better vs. Celebrex (celecoxib)
Have you used Lodine (etodolac)?
Worth itNot sureNot worth it
Reviews for Aleve (naproxen)
78%
+21% better vs. Celebrex (celecoxib)
48%
+10% better vs. Celebrex (celecoxib)
5%
+9% better vs. Celebrex (celecoxib)
978 reviews
Have you used Aleve (naproxen)?
Worth itNot sureNot worth it
Reviews for Relafen (nabumetone)
Not enough review data. Review it!
-24% worse vs. Celebrex (celecoxib)
Not enough review data. Review it!
-5% worse vs. Celebrex (celecoxib)
Not enough review data. Review it!
+14% better vs. Celebrex (celecoxib)
Have you used Relafen (nabumetone)?
Worth itNot sureNot worth it
Reviews for Percocet (oxycodone / acetaminophen)
70%
+13% better vs. Celebrex (celecoxib)
49%
+11% better vs. Celebrex (celecoxib)
15%
-1% worse vs. Celebrex (celecoxib)
1399 reviews
Have you used Percocet (oxycodone / acetaminophen)?
Worth itNot sureNot worth it
Reviews for Norco (hydrocodone / acetaminophen)
67%
+10% better vs. Celebrex (celecoxib)
44%
+6% better vs. Celebrex (celecoxib)
13%
+1% better vs. Celebrex (celecoxib)
1194 reviews
Have you used Norco (hydrocodone / acetaminophen)?
Worth itNot sureNot worth it
Reviews for Ultram (tramadol)
61%
+4% better vs. Celebrex (celecoxib)
40%
+2% better vs. Celebrex (celecoxib)
16%
-2% worse vs. Celebrex (celecoxib)
642 reviews
Have you used Ultram (tramadol)?
Worth itNot sureNot worth it
Reviews for Tylenol Regular Strength (acetaminophen)
77%
+20% better vs. Celebrex (celecoxib)
37%
-1% worse vs. Celebrex (celecoxib)
3%
+11% better vs. Celebrex (celecoxib)
1002 reviews
Have you used Tylenol Regular Strength (acetaminophen)?
Worth itNot sureNot worth it
Reviews for Ms Contin (morphine sulfate)
55%
-2% worse vs. Celebrex (celecoxib)
43%
+5% better vs. Celebrex (celecoxib)
20%
-6% worse vs. Celebrex (celecoxib)
541 reviews
Have you used Ms Contin (morphine sulfate)?
Worth itNot sureNot worth it
Reviews for Zorvolex (diclofenac)
Not enough review data. Review it!
+43% better vs. Celebrex (celecoxib)
Not enough review data. Review it!
+62% better vs. Celebrex (celecoxib)
Not enough review data. Review it!
+14% better vs. Celebrex (celecoxib)
Have you used Zorvolex (diclofenac)?
Worth itNot sureNot worth it
Reviews for Advil (ibuprofen)
88%
+31% better vs. Celebrex (celecoxib)
52%
+14% better vs. Celebrex (celecoxib)
4%
+10% better vs. Celebrex (celecoxib)
892 reviews
Have you used Advil (ibuprofen)?
Worth itNot sureNot worth it
Side effects
CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen

We haven’t found good data for Celebrex side effects.

FDA side effect reports for Celebrex »
  • Indigestion 10%
  • Ear, nose, or throat infection 8%
  • Nausea 7%
  • Urinary tract infection 7%
  • Pain 5%
  • Abdominal pain 3%
  • Constipation 3%
  • Diarrhea 3%
  • Gas 3%
  • Vomiting 3%
More meloxicam side effects »

We haven’t found good data for Lodine side effects.

FDA side effect reports for Lodine »

The Naproxen FDA package insert doesn’t have numbers about how common side effects are.

More about Naproxen side effects »

We haven’t found good data for Relafen side effects.

FDA side effect reports for Relafen »

The Percocet FDA package insert doesn’t have numbers about how common side effects are.

More about Percocet side effects »

The Norco FDA package insert doesn’t have numbers about how common side effects are.

More about Norco side effects »
  • Dizziness 26%
  • Constipation 24%
  • Nausea 24%
  • Headache 18%
  • Sleepiness 16%
  • Vomiting 9%
  • Itching 8%
  • Cns stimulation 7%
  • Muscle weakness 6%
  • Sweating 6%
More Tramadol side effects »

We haven’t found good data for Tylenol side effects.

FDA side effect reports for Tylenol »

The Morphine Sulfate FDA package insert doesn’t have numbers about how common side effects are.

More about Morphine Sulfate side effects »
  • Swelling due to excess fluid 1%
  • Constipation 4%
  • Itching 1%
  • Passing gas 1%
  • Pain in extremity 2%
  • Indigestion 1%
More Diclofenac side effects »

The ibuprofen FDA package insert doesn’t have numbers about how common side effects are.

More about ibuprofen side effects »
How it works
CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen
Celebrex (Celecoxib) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.Mobic (meloxicam) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves pain and swelling.Coming soon.Aleve (Naproxen) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.Coming soon.Percocet (Oxycodone / Acetaminophen) is a combination pain medicine. Oxycodone is an opioid (similar to morphine) that works in the brain to lower pain perception. Acetaminophen is a non-opioid pain reliever and fever reducer.Norco (Hydrocodone / Acetaminophen) is a combination pain medicine. Hydrocodone is an opioid (similar to morphine) that works in the brain to lower pain perception. Acetaminophen is a non-opioid pain reliever and fever reducer.Ultram (tramadol) is an opioid pain reliever. Researchers don't know exactly how it works, but it alters certain brain chemicals to lower pain perception and improve mood.Tylenol Regular Strength (Acetaminophen) reduces fever and relieves pain, but doesn't lower inflammation and swelling.Ms Contin (Morphine Sulfate) is an opioid medicine that works in the brain to lower pain perception.Zorvolex (Diclofenac) is a non-steroidal anti-inflammatory drug (NSAID). It stops your body from making chemicals that cause inflammation and pain.Advil (ibuprofen) is a non-steroidal anti-inflammatory drug (NSAID). It stops the inflammation process in your body, which relieves pain, swelling, and fever.
Type of medication
CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen
Prescription only
Prescription only
Prescription or OTC
Prescription only
Prescription only
Prescription only
Over-the-counter
Prescription only
Prescription only
Over-the-counter
Available as
CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen
  • Pill
  • Pill
  • Suspension
  • Pill
  • Extended release
  • Pill
  • Delayed release tablet
  • Liquid
  • Pill
  • Pill
  • Oral solution
  • Pill
  • Oral solution
  • Pill
  • Extended release
  • Extended release capsule
  • Dissolving tablet
  • Pill
  • Extended release tablet
  • Chewable tablet
  • Dissolving tablet
  • Gelcap
  • Liquid
  • Suppository
  • Pill
  • Extended release
  • Oral solution
  • Liquid
  • Suppository
  • Pill
  • Pill
  • Chewable tablet
  • Suspension
Used for
CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen
  • Juvenile Rheumatoid Arthritis Osteoarthritis Pain Rheumatoid Arthritis
  • Osteoarthritis Rheumatoid Arthritis
  • Osteoarthritis Pain
Risk factors for serious side effects
CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen
  • Long-term use
  • History of heart disease
  • History of heart bypass surgery (coronary artery bypass graft/CABG)
  • Age 65 or older
  • History of GI bleed or peptic ulcer disease
Detailed Celebrex (celecoxib) risks & warnings »
  • History of heart problems
  • Taking the medicine for a long period of time
  • History of stomach bleeding
  • Age 60 or older
  • Taking aspirin, other NSAIDs, or blood thinners
Detailed Mobic (meloxicam) risks & warnings »
    Coming soon.
    • History of heart problems
    • High blood pressure
    • High cholesterol
    • Diabetes
    • Smoking
    Detailed Aleve (naproxen) risks & warnings »
      Coming soon.
      • Current liver disease
      • Taking with alcohol
      • Taking other medicines with acetaminophen
      • Age 65 or greater
      • Higher dose
      Detailed Percocet (oxycodone / acetaminophen) risks & warnings »
      • Current liver disease
      • Taking with alcohol
      • Taking other medicines with acetaminophen
      • Age 65 or greater
      • Higher dose
      Detailed Norco (hydrocodone / acetaminophen) risks & warnings »
      • Pregnancy
      • Age 65 or greater
      • Overdose
      • Using alcohol, benzodiazepines or other medicines that slow breathing
      • Taking more than the prescribed dose
      Detailed Ultram (tramadol) risks & warnings »
      • Drinking more than 2 alcoholic beverages a day
      • Taking with other Tylenol-containing medicines
      • History of liver disease
      Detailed Tylenol Regular Strength (acetaminophen) risks & warnings »
      • Current use of medicine that affects liver enzyme CYP 3A4
      • Age 65 or greater
      • Higher dose
      • People with not enough thyroid hormones
      • History of lung problems
      Detailed Ms Contin (morphine sulfate) risks & warnings »
      • History of heart problems
      • High blood pressure
      • High cholesterol
      • Diabetes
      • Being overweight or obese
      Detailed Zorvolex (diclofenac) risks & warnings »
      • History of heart problems
      • Taking Advil (ibuprofen) for a long period of time
      • History of stomach bleeding
      • Age 60 or older
      • Taking aspirin, other NSAIDs, or blood thinners
      Detailed Advil (ibuprofen) risks & warnings »
      Pregnancy

      Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Interactions
      CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen
      No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.
      • Ultram (tramadol) can interact with your other medicines, which can change how it affects your pain. Stopping these medicines while taking Ultram (tramadol) can make you more likely to have serious, life threatening side effects. Make sure your doctor and pharmacist know all the medicines you're taking, and let them know of any changes.
      No interactions related info.No interactions related info.No interactions related info.No interactions related info.
      Alcohol
      CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen
      No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.
      • Avoid alcohol.
      • Avoid alcohol.
      No alcohol related info.
      • Drinking alcohol while taking Tylenol Regular Strength (Acetaminophen) can damage your liver.
      • Heavy alcohol drinkers shouldn't use Tylenol Regular Strength (Acetaminophen) since it can cause serious liver damage.
      No alcohol related info.
      • You should avoid alcohol while on Zorvolex (Diclofenac) since it can increase your risk of stomach issues.
      • Don't drink alcohol while using Zorvolex (Diclofenac).
      No alcohol related info.
      Food
      CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen
      • Take it with a meal or a snack to prevent an upset stomach.
      • It should be taken only once a day, with food or milk to prevent stomach upset.
      No food related info.
      • It needs to be taken with food to avoid getting an upset stomach.
      • Take it with a meal or a snack to prevent an upset stomach.
      No food related info.
      • Take it with food to lower the chance of an upset stomach.
      • Take it with food to lower the chance of an upset stomach.
      • Take Ultram (tramadol) with food to avoid an upset stomach.
      No food related info.
      • Take it with food to lower the chance of an upset stomach.
      • Take it with food to avoid getting diarrhea.
      • It needs to be taken with food or millk to avoid getting an upset stomach.
      • Take it with food or milk to prevent stomach upset.
      Kidneys and liver
      CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen
      • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
      • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
      • Celebrex (Celecoxib), and similar medications in the NSAID family, can cause lower kidney function or cause permanent kidney damage. You're at higher risk for this if you've a history of kidney disease, heart failure, and liver disease. Taking Diuretic, ACE inhibitor, or Angiotensin Receptor Blocker (ARB) medications also increases your risk. If you are 65 or older you're also at a higher risk for these types of kidney problems.
      • Mobic (meloxicam) can damage your kidneys if you take it for a very long time. Taking the lowest dose for the shortest amount of time lowers your risk. Talk to your doctor if this worries you, or if you already have kidney damage before you start taking Mobic (meloxicam).
      No kidneys and liver related info.
      • It can cause serious kidney and stomach problems (like ulcers and bleeding) the longer you take it.
      • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
      • Aleve (Naproxen) is an NSAID that can lower kidney function or cause damage. Taking the lowest dose for the shortest amount of time lowers your risk. Your doctor should check your kidney function if you take Aleve (Naproxen) for any amount of time.
      No kidneys and liver related info.
      • Don't take more than instructed to prevent liver damage.
      • The acetaminophen component in Percocet (Oxycodone / Acetaminophen) can hurt your liver. Using more than 4000 mg of the acetaminophen (or 12 tablets of Percocet (Oxycodone / Acetaminophen) can cause serious harm to your liver that may make you need a liver transplant and can be life-threatening. Don't take more than your doctor prescribes, and avoid other medicines that have acetaminophen when using Percocet (Oxycodone / Acetaminophen).
      • Don't take more than instructed to prevent liver damage.
      • The acetaminophen component in Norco (Hydrocodone / Acetaminophen) can hurt your liver. Using more than 4000 mg of the acetaminophen (or 12 tablets of Norco (Hydrocodone / Acetaminophen) can cause serious harm to your liver. You may develop life-threatening liver problems that need a liver transplant. Don't take more than your doctor prescribes, and avoid other medicines that have acetaminophen when using Norco (Hydrocodone / Acetaminophen).
      • There are different doses for people who are older or who have liver or kidney disease, so work with your doctor to get the right dose.
      • Doesn't cause kidney damage and is safe to use if you have heart problems or if you're pregnant.
      • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it's a very common ingredient in pain and cold/flu combination medicines.
      No kidneys and liver related info.
      • Zorvolex (Diclofenac), and similar medications in the NSAID family, can lower kidney function or cause permanent kidney damage. Taking the lowest dose for the shortest amount of time necessary can lower your risk of kidney problems. It's important to get lab tests to check your kidney function periodically if you use Zorvolex (Diclofenac) for long periods of time.
      • Advil (ibuprofen) can damage your kidneys. Taking the lowest dose for the shortest amount of time lowers your risk. Talk to your doctor if this worries you, or if you already have kidney damage before you start taking Advil (ibuprofen).
      Pain
      CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen
      • Relieves pain and inflammation for many types of arthritis, including osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
      • Good for treating muscle aches and pains, as well as menstrual cramps.
      • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
      • Works well to relieve pain and inflammation due to osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
      • Mobic (meloxicam) can cause stomach bleeding which can be dangerous. If you notice blood in your vomit or your stool has bright red blood or looks like black coffee grounds, or if you have pain in your stomach that doesn't go away, talk to your doctor right away.
      No pain related info.
      • Works well to relieve pain, swelling, and fevers.
      • Starts relieving pain in 30 to 60 minutes.
      • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
      No pain related info.
      • Combination pain medicine with an opioid component (oxycodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
      • Generally considered stronger than Norco or other combination pain medicine for treating pain.
      • This is a combination pain medication. It contains both an opioid medicine, and acetaminophen (Tylenol).
      • Works best if you take it as soon as you start feeling pain.
      • Pain relief lasts 4-6 hours.
      • Talk to your doctor if it doesn't work well enough to relieve your pain, or if the side effects are really bad.
      • Combination pain medicine with an opiod component (hydrocodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
      • This is a combination pain medication. It contains both an opioid medicine and acetaminophen (Tylenol).
      • Works best if you take it as soon as you start feeling pain. Starts working in 30 minutes and pain relief lasts 4 to 6 hours.
      • Talk to your doctor if it doesn't work well enough to relieve your pain, or if the side effects are really bad.
      • Relieves moderate to severe pain. It has been shown to work as well as other opioid pain medications.
      • The extended release version of Ultram (tramadol) should only be used for severe pain that requires daily, around-the-clock treatment once alternative treatments haven't worked.
      • Ultram (tramadol) can interact with your other medicines, which can change how it affects your pain. Stopping these medicines while taking Ultram (tramadol) can make you more likely to have serious, life threatening side effects. Make sure your doctor and pharmacist know all the medicines you're taking, and let them know of any changes.
      • Works well to relieve pain and fevers.
      • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it's a very common ingredient in pain and cold/flu combination medicines.
      • Good for chronic pain that requires around-the-clock relief.
      • Doesn't work for as-needed or quick pain relief.
      • Clinical studies show that Zorvolex (Diclofenac) is better at relieving arthritis pain than acetaminophen (Tylenol).
      • Can be used as needed to treat pain and swelling.
      • Can cause swelling in your legs, abdominal pain, constipation, diarrhea, and an upset stomach.
      • Good for relieving pain due to common conditions like menstrual cramps, toothaches, backaches, and sports-related injuries.
      • Do not take for more than 10 days for pain relief or more than 3 days for fever. Talk to your doctor if your symptoms do not go away.
      Sleep
      CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen
      No sleep related info.No sleep related info.No sleep related info.No sleep related info.No sleep related info.
      • Can help you fall asleep easier.
      • Dizziness and drowsiness is common, but your body may adjust.
      • Can help you fall asleep easier.
      • Dizziness and drowsiness is common.
      No sleep related info.No sleep related info.
      • Dizziness and drowsiness is common, but your body may adjust.
      No sleep related info.No sleep related info.
      Upsides and benefits
      CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen
      • Relieves pain and inflammation for many types of arthritis, including osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
      • Good for treating muscle aches and pains, as well as menstrual cramps.
      • Causes fewer stomach problems than other NSAIDs like Ibuprofen or Naproxen.
      • Lasts longer than Ibuprofen.
      • Taken only once a day, while other NSAIDS need to be taken a few times a day for the same effect.
      • Works well to relieve pain and inflammation due to osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
      • Causes less stomach upset than other NSAIDs.
      • Relatively cheap compared to other prescription NSAIDS.
      Coming soon
      • Works well to relieve pain, swelling, and fevers.
      • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
      • Lasts longer than Ibuprofen, so you can take it less often.
      • Aleve (Naproxen) works as well as Aspirin and Indomethacin to treat arthritis pain, and causes fewer stomach problems.
      • Although not without side effects, it's been around for a long time and is generally safe for short-term use.
      Coming soon
      • Combination pain medicine with an opioid component (oxycodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
      • Provides quick relief for moderate to severe pain to improve quality of life.
      • Generally considered stronger than Norco or other combination pain medicine for treating pain.
      • Good for as-needed, short-term use, but may be helpful to manage more long-term pain problems if used at the appropriate doses and intervals.
      • Lower rates of misuse compared to pure opioid medicines.
      • Can help you fall asleep easier.
      • Combination pain medicine with an opiod component (hydrocodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
      • Provides quick relief for moderate to severe pain to improve quality of life.
      • Good for as-needed, short-term use, but may be helpful to manage more long-term pain problems if used at the appropriate doses and intervals.
      • Generally well tolerated by people, especially if taken with food to lower risk of stomach upset.
      • Lower rates of misuse compared to pure opioid medicines.
      • Can help you fall asleep easier.
      • Relieves moderate to severe pain. It has been shown to work as well as other opioid pain medications.
      • Compared to typical opioids, it provides unique pain relief and effects on your mood when taken regularly.
      • Has a lower chance of causing breathing problems compared to other typical opioids.
      • Doesn't cause as much constipation as other opioid pain medicines. Staying hydrated and taking laxatives can help treat this side effect.
      • Works well to relieve pain and fevers.
      • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
      • Tylenol Regular Strength (Acetaminophen) causes less upset stomach, ulcers, bruising, and bleeding than other pain medications like aspirin, ibuprofen, and naproxen.
      • Doesn't cause kidney damage and is safe to use if you have heart problems or if you're pregnant.
      • Although not without side effects, it's been around for a long time and is generally safe for short-term use.
      • Provides longer relieve for moderate to severe pain to improve quality of life.
      • Good for chronic pain that requires around-the-clock relief.
      • Might have fewer side effects than other opioid pain relievers.
      • Clinical studies show that Zorvolex (Diclofenac) is better at relieving arthritis pain than acetaminophen (Tylenol).
      • Can be used as needed to treat pain and swelling.
      • Available as a generic.
      • Advil (ibuprofen) is effective for treating fever, pain, and inflammation.
      • Good for relieving pain due to common conditions like menstrual cramps, toothaches, backaches, and sports-related injuries.
      • Advil (ibuprofen) is generally safe to use, cheap, and available over-the-counter.
      • Advil (ibuprofen) causes less stomach problems than its alternatives.
      • It comes in different flavored liquid forms that makes it easy for children to take.
      Downsides and risks
      CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen
      • The longer you take Celebrex (Celecoxib), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding. Can also happen if you take Celebrex (Celecoxib) on an empty stomach.
      • Like all NSAIDs, it can raise your risk of blood clots, heart attack, or a stroke.
      • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
      • Mobic (meloxicam) does not kick in as fast as other NSAIDS.
      • It's available by prescription only.
      • Mobic (meloxicam) is not as safe as other alternatives for pregnant women and people who are age 60 or older.
      • It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
      Coming soon
      • It needs to be taken with food to avoid getting an upset stomach.
      • Can't be taken by pregnant women.
      • It can cause serious kidney and stomach problems (like ulcers and bleeding) the longer you take it.
      • Like all NSAIDs, it can raise your risk of having blood clots, heart attack, or stroke.
      Coming soon
      • Dizziness and drowsiness is common, but your body may adjust.
      • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Percocet if you need.
      • All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
      • The non-opioid part of Percocet, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
      • Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
      • Avoid alcohol.
      • Dizziness and drowsiness is common.
      • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Norco if you need.
      • All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
      • The non-opioid part of Norco, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
      • Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
      • Avoid alcohol.
      • Some people think it's weaker than other opioid pain medications. It can also cause more upset stomach.
      • Like other opioid pain relievers, Ultram (tramadol) has a high risk of addiction, abuse, misuse, overdose, and death.
      • The extended release version of Ultram (tramadol) should only be used for severe pain that requires daily, around-the-clock treatment once alternative treatments haven't worked.
      • It's a controlled substance regulated by the federal government. This means that your use of Ultram (tramadol) will be tracked to prevent potential prescription abuse.
      • Like all opioids, don't use when pregnant, since the baby can become dependent on it and have withdrawal symptoms after birth.
      • Tylenol Regular Strength (Acetaminophen) doesn't treat pain as well as other medications like ibuprofen and naproxen.
      • Drinking alcohol while taking Tylenol Regular Strength (Acetaminophen) can damage your liver.
      • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it's a very common ingredient in pain and cold/flu combination medicines.
      • Heavy alcohol drinkers shouldn't use Tylenol Regular Strength (Acetaminophen) since it can cause serious liver damage.
      • Doesn't work for as-needed or quick pain relief.
      • Dizziness and drowsiness is common, but your body may adjust.
      • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Ms Contin (Morphine Sulfate) if you need.
      • Long term use will likely cause physical dependence.
      • Must be weaned slowly off the medicine after use longer than 2 weeks.
      • You should avoid alcohol while on Zorvolex (Diclofenac) since it can increase your risk of stomach issues.
      • If you're taking it on a regular basis, you'll need to get labs done to make sure your liver and kidneys aren't being affected.
      • Advil (ibuprofen) doesn't last as long as other NSAIDs, so you need to take it a few times a day to get relief of your symptoms.
      • It needs to be taken with food or millk to avoid getting an upset stomach.
      • Advil (ibuprofen) is not as safe as other alternatives for pregnant women and people who are age 60 or older.
      • It can cause serious complications like stomach bleeding and kidney problems if taken for a long period of time.
      • Like all NSAIDs, Advil (ibuprofen) can raise your risk of getting blood clots, a heart attack, or stroke.
      Tips from our pharmacists for people taking the medication
      CelebrexmeloxicamLodineNaproxenRelafenPercocetNorcoTramadolTylenolMorphine SulfateDiclofenacibuprofen
      • Starts working in 1 to 3 hours.
      • Take it with a meal or a snack to prevent an upset stomach.
      • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
      • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
      • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
      • It should be taken only once a day, with food or milk to prevent stomach upset.
      • Mobic (meloxicam) increases the risk of stomach bleeding so tell your doctor right away if you experience any bleeding.
      • Do not take Mobic (meloxicam) with any blood thinners unless your doctor says so.
      • If you are allergic to aspirin, you may be allergic to Mobic (meloxicam) as well.
      • The capsule, suspension, and tablet forms of the medicine come in different strengths, so be careful when switching from one form to another.
      Coming soon
      • Starts relieving pain in 30 to 60 minutes.
      • Take it with a meal or a snack to prevent an upset stomach.
      • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
      • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
      • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
      Coming soon
      • This is a combination pain medication. It contains both an opioid medicine, and acetaminophen (Tylenol).
      • Starts working in 30 minutes.
      • Works best if you take it as soon as you start feeling pain.
      • Pain relief lasts 4-6 hours.
      • Can make you dizzy or drowsy.
      • Avoid activities need you to be fully alert until you know how it affects you.
      • Take it with food to lower the chance of an upset stomach.
      • Constipation is common and may not go away while you're taking this medicine. Drinking lots of water and using laxatives can help.
      • Don't take more than instructed to prevent liver damage.
      • Use it for the shortest time possible, and at the lowest dose possible, to lower your chance of becoming addicted.
      • Talk to your doctor if it doesn't work well enough to relieve your pain, or if the side effects are really bad.
      • This is a combination pain medication. It contains both an opioid medicine and acetaminophen (Tylenol).
      • Works best if you take it as soon as you start feeling pain. Starts working in 30 minutes and pain relief lasts 4 to 6 hours.
      • Can make you dizzy or drowsy. Avoid activities need you to be fully alert until you know how it affects you.
      • Take it with food to lower the chance of an upset stomach.
      • Constipation is common and may not go away while you're taking this medicine. Drinking lots of water and using laxatives can help.
      • Don't take more than instructed to prevent liver damage.
      • Use it for the shortest time and at the lowest dose possible, to lower your chance of becoming addicted.
      • Talk to your doctor if it doesn't work well enough to relieve your pain, or if the side effects are really bad.
      • Starts working in one hour and works best if you take it regularly.
      • Can make you dizzy or drowsy, so avoid activities that need you to be fully alert until you know how this medicine affects you.
      • Take Ultram (tramadol) with food to avoid an upset stomach.
      • There are different doses for people who are older or who have liver or kidney disease, so work with your doctor to get the right dose.
      • Swallow the extended-release tablets whole. They're designed to release the drug slowly and breaking, crushing, or chewing them could cause a serious overdose.
      • Take the extended-release tablets exactly as your doctor and pharmacist tell you. If you forget, take it as soon as you remember. Don't take extra medicine to make up for a missed dose.
      • Starts working in one hour.
      • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
      • Follow age-specific dosing instructions on how much to take. Adults should never take more than 3,000 milligrams (mg) in a single day.
      • Let your doctor know if your symptoms don't improve in a few days.
      • Opioid pain medicine that provides longer pain relief—up to 12 hours.
      • Works best when taken regularly instead of as-needed.
      • Especially useful for people with chronic pain problems.
      • May not be the best choice for people who have never taken an opioid pain medicine because it lasts so long.
      • Swallow it whole. Don't crush, chew, or split the medicine.
      • Can make you dizzy or drowsy.
      • Avoid activities that need you to be fully alert until you know how it affects you.
      • Take it with food to lower the chance of an upset stomach.
      • Constipation is common and may not go away while you're taking this medicine. Drinking lots of water and taking laxatives can help.
      • Talk to your doctor if it doesn't help enough for your pain, or if the side effects are really bad.
      • Take it with food to avoid getting diarrhea.
      • Don't drink alcohol while using Zorvolex (Diclofenac).
      • Don't take other anti-inflammatory medications (NSAIDs) without talking to your doctor or pharmacist.
      • Can cause swelling in your legs, abdominal pain, constipation, diarrhea, and an upset stomach.
      • Don't take antacids with magnesium since they can interact with Zorvolex (Diclofenac).
      • Take Zorvolex (Diclofenac) at the smallest dose possible for the shortest amount of time to prevent an increased risk of heart attack.
      • Starts working in about 30 to 60 minutes.
      • Take it with food or milk to prevent stomach upset.
      • Do not take for more than 10 days for pain relief or more than 3 days for fever. Talk to your doctor if your symptoms do not go away.
      • If you normally take a daily aspirin, make sure to take Advil (ibuprofen) at least 30 minutes after taking aspirin or more than 8 hours before taking aspirin. This will help make sure the aspirin still works in your body.
      • Advil (ibuprofen) increases the risk of stomach bleeding so tell your doctor right away if you experience any bleeding.
      • If you are allergic to aspirin, there is a chance you may be allergic to Advil (ibuprofen) as well.
      Learn more
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