Prescription onlyLower-cost generic availableClass: Mental health



Prescription onlyLower-cost generic availableClass: Mental health
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Improves mood and helps you relax.

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Our bottom line

Celexa (Citalopram) is good for treating depression and anxiety. Might be less likely to cause side effects than some antidepressants, but not the best choice for people with heart or liver problems.

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  • Effective at relieving depression and anxiety symptoms.
  • Causes less sleepiness compared to other antidepressants.
  • Six out of ten people who use an antidepressant for the first time find that it works for them.
People say this drug is:
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  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
  • Can cause minor weight gain (1 to 5 pounds).
  • Celexa (Citalopram) can cause an irregular heartbeat if you take a high dose (40 mg a day, or more).
  • Not a good option for you if you have heart or liver problems.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24 years.
  • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
How it works

Celexa (Citalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.

What to expect when you take Celexa (citalopram) for Depression

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Side effect rates for Celexa (citalopram)

1509 From clinical trials of Celexa / Depression
  • Nausea
  • Dry mouth
  • Drowsiness
  • Sleep difficulty
  • Sweating increased
  • Diarrhea
  • Tremor
  • Ejaculation disorder
  • Inflammation inside the nose
  • Indigestion

Risks and Warnings for Celexa (citalopram)

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    • Higher risk if:
    • Age 24 years or younger

    Celexa (Citalopram) may increase the risk of suicidal thoughts or behavior. Watch for worsening depression or any unusual changes in mood or behavior, especially during the first few months of treatment or when the dose changes. Report anything concerning to a doctor immediately. Celexa (Citalopram) is not approved for use in children younger than age 18.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Celexa (citalopram)

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  • Don't drink alcohol
  • Take with food to avoid upset stomach.
Kidneys and liver
  • Not a good option for you if you have heart or liver problems.
  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
  • I have no libido which has caused friction between my partner.
  • Caused decreased libido at first.
  • The first and most noticeable side effect for me was drowsiness. This effect fades with prolonged use. Otherwise citalopram has, for me, the lowest occurrence of side effects of any antidepressant I've tried, including Zoloft, Wellbutrin, Lexapro, and Effexor. Did not cause sexual side effects for me. Does cause excessive sweating, but nothing that an extra strength anti-perspirant and baby powder can't handle.
  • Take later at night. May make you very sleepy.
  • Sleep disturbances are possible
  • Can cause minor weight gain (1 to 5 pounds).
  • Be sure to take it at the same time every day. I get horrible, migraine-like headaches if I take it late. Also, I've gained so much weight since taking it.
  • I gained a lot of weight but I'm alive. And my suicidal depression had no cure until Citalopram.
  • I gained some biggie.