Cenestin

(Synthetic Conjugated Estrogens)

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3.86Cenestin

Relieves hot flashes and vaginal dryness due to menopause.

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Our bottom line

Cenestin (Synthetic Conjugated Estrogens) relieves menopausal symptoms. It's an oral hormone replacement, so it can have a lot of side effects, and it's important to think through the benefits and potential hassles of this drug before using it.

Quick facts about Cenestin
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available
Prices and discounts
Lowest price for 30 0.3mg tablets
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$116.66

Upsides

  • Cenestin (Synthetic Conjugated Estrogens) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen (hot flashes, night sweats, vaginal dryness).
  • Lowers your risk of fractures by keeping your bones healthy. Make sure you also take enough calcium and Vitamin D.
  • Improves mood, energy, and mental alertness for some people.
  • Does not expose your partner to estrogen during sexual acitivities like vaginal estrogen creams.
People’s experience with Cenestin

37reviews so far. What do you think?

Worth itNot sureNot worth it

Downsides

  • More potential side effects than estrogen creams since it exposes your whole body to estrogen.
  • Increases your risk of uterine and breast cancer.
  • If you have your uterus, you have to take Cenestin (Synthetic Conjugated Estrogens) with another hormone called progestin to lower your risk of uterine cancer.
  • Increases your risk of developing blood clots and stroke.
  • Can't be used in people with liver problems.
  • Can be expensive since it's only available as a brand name product.
How it works

Cenestin (Synthetic Conjugated Estrogens) is an oral medication that replaces estrogen hormones during and after menopause. Higher levels of estrogen lower menopause-related hot flashes, flushing, night sweats, vaginal problems, and bone loss.

Quick facts about Cenestin
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Hot flashes and night sweats
  • Vaginal dryness and inflammation

Dosage forms

  • Pill
People’s experience with Cenestin

37reviews so far. What do you think?

Worth itNot sureNot worth it
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Side effect rates for Cenestin (Synthetic Conjugated Estrogens)

103 From clinical trials of Cenestin / Postmenopausal estrogen replacement (0.45 mg)
  • Infection
  • Pharyngitis
  • Vasodilations
  • Myalgia
  • Depression
  • Nervousness
  • Palpitations
  • Weight increase
  • Anxiety
  • Insomnia

Risks and Warnings for Cenestin (Synthetic Conjugated Estrogens)

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    • Higher risk if:
    • Using estrogen for more than one year

    Vaginal bleeding after menopause can be a warning sign of uterus (endometrial) cancer, so let your doctor know if you notice any unusual bleeding. When estrogen is prescribed to women after menopause who still have a uterus, progestin should be used with it to lower the risk of cancer. Low-dose vaginal estrogen products are often a better choice than oral pills for women 65 years or older who have vaginal symptoms.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Cenestin (Synthetic Conjugated Estrogens)

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Pregnancy
Pain
  • Get emergency care if you notice swelling or pain in your lower legs, sudden shortness of breath, or an unexplained severe headache.
Weight
  • Can cause nausea, dizziness, bloating and breast tenderness.