Relieves hot flashes and vaginal dryness due to menopause.
Our pharmacists’ bottom line
Cenestin (Synthetic Conjugated Estrogens) relieves menopausal symptoms. It's an oral hormone replacement, so it can have a lot of side effects, and it's important to think through the benefits and potential hassles of this drug before using it.
- Cenestin (Synthetic Conjugated Estrogens) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen (hot flashes, night sweats, vaginal dryness).
- Lowers your risk of fractures by keeping your bones healthy. Make sure you also take enough calcium and Vitamin D.
- Improves mood, energy, and mental alertness for some people.
- Does not expose your partner to estrogen during sexual acitivities like vaginal estrogen creams.
- More potential side effects than estrogen creams since it exposes your whole body to estrogen.
- Increases your risk of uterine and breast cancer.
- If you have your uterus, you have to take Cenestin (Synthetic Conjugated Estrogens) with another hormone called progestin to lower your risk of uterine cancer.
- Increases your risk of developing blood clots and stroke.
- Can't be used in people with liver problems.
- Can be expensive since it's only available as a brand name product.
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- (30) 0.3mg tablet
- Cost for (30) 0.3mg tablets of Cenestin (Synthetic Conjugated Estrogens) at pharmacies
Side effects for Cenestin (Synthetic Conjugated Estrogens)
From clinical trials of Cenestin / Postmenopausal estrogen replacement (0.45 mg) ( 103)
- Endometrial thickeningEndometrial thickening36% for Cenestin vs.8% for placebo
- Ear, nose, or throat infectionEar, nose, or throat infection13% for Cenestin vs.2% for placebo
- Muscle weaknessMuscle weakness11% for Cenestin vs.14% for placebo
- PainPain11% for Cenestin vs.2% for placebo
- HeadacheHeadache11% for Cenestin vs.16% for placebo
- Pain abdominalPain abdominal9% for Cenestin vs.6% for placebo
- NauseaNausea9% for Cenestin vs.4% for placebo
- Joint painJoint pain9% for Cenestin vs.10% for placebo
- Tingling sensationTingling sensation8% for Cenestin vs.6% for placebo
- VaginitisVaginitis8% for Cenestin vs.2% for placebo
What to expect when you take Cenestin (Synthetic Conjugated Estrogens)Skip what to expect section. Skip to Risks & Warnings section.
- Take Cenestin (Synthetic Conjugated Estrogens) at the same time each day. If you miss a dose, take it as soon as possible, but if it’s almost time for your next dose, take only that dose.
- Use the lowest dose possible of Cenestin (Synthetic Conjugated Estrogens) and take it only as long as needed. Talk to your doctor regularly to see if you still need treatment. If you’re taking Cenestin (Synthetic Conjugated Estrogens) only for vaginal symptoms or to prevent bone loss, there are other medicines that can work better with fewer side effects (like a vaginal cream for menopause symptoms, or non-estrogen medicine for bone loss).
- Can cause nausea, dizziness, bloating and breast tenderness.
- Get emergency care if you notice swelling or pain in your lower legs, sudden shortness of breath, or an unexplained severe headache.
- Tell your doctor about any unusual vaginal bleeding.
Risks and Warnings for Cenestin (Synthetic Conjugated Estrogens)Skip Risks and Warnings section. Skip to Tips section.
- Higher risk if:
- › Using estrogen for more than one year
Vaginal bleeding after menopause can be a warning sign of uterus (endometrial) cancer, so let your doctor know if you notice any unusual bleeding. When estrogen is prescribed to women after menopause who still have a uterus, progestin should be used with it to lower the risk of cancer. Low-dose vaginal estrogen products are often a better choice than oral pills for women 65 years or older who have vaginal symptoms.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.
Tips from pharmacists and people taking Cenestin (Synthetic Conjugated Estrogens)Final section. Do you want to return to drug navigation?
- Upsides and downsides from our pharmacists
- › Does not expose your partner to estrogen during sexual acitivities like vaginal estrogen creams.