Prescription onlyClass: women's health



Prescription onlyClass: women's health
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Helps kick start or continue labor in women who are ready to deliver a full-term baby.

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Our bottom line

Cervidil (dinoprostone) is a vaginal product used to start labor, but there are a lot of medical conditions that make it unsafe to use.

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  • Only need one dose for it to work.
  • Very effective at starting labor.
  • Speeds up labor and delivery by several hours.
  • Does not require any needles or injections.
  • Side effects are rare.


  • Can lead to fetal distress (baby's heart rate drops).
  • Can't be used if you have had uterine surgeries of any kind before, including a previous c-section.
  • Can't be used if you have had 6 or more full term pregnancies.
  • You must lie down for 2 hours after inserting.
How it works

Cervidil (dinoprostone) is a hormone found naturally throughout the body called prostaglandin E2. When given to a pregnant woman to start labor, it helps relax and widen the cervix so the baby can be delivered.

What to expect when you take Cervidil (dinoprostone) for Labor induction

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Side effect rates for Cervidil (dinoprostone)

658 From clinical trials of Cervidil / Labor induction (10 mg)
  • Labor complications without fetal distress
  • Fetal distress
  • Labor complications with fetal distress

Risks and Warnings for Cervidil (dinoprostone)

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    • Higher risk if:
    • Age 30 and older
    • Complications during pregnancy
    • More than 40 weeks pregnant before labor

    Women over 30, those who experienced complications during pregnancy, and those who are more than 40 weeks pregnant before they deliver are more likely to have bleeding problems or blood clots right after giving birth. Cervidil (dinoprostone) raises this risk. If you use this medicine, your doctor may have to run blood tests and will watch you closely to make sure you do not develop any bleeding problems or blood clots.