Prescription onlyLower-cost generic availableClass: Cardiovascular

Thalitone Alternatives

(chlorthalidone)

Prescription onlyLower-cost generic availableClass: Cardiovascular
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Compare Thalitone (chlorthalidone) to alternatives

These medications are comparable to Thalitone (chlorthalidone) or used for similar purposes.

Thalitone
(chlorthalidone)

Lasix
(furosemide)

Aldactone
(spironolactone)

Edecrin
(ethacrynic acid)

Bumex
(bumetanide)

Lowers blood pressure. Removes extra water from your body. Thalitone (chlorthalidone) is a well-tolerated water pill that's increasingly used to treat high blood pressure.Lowers blood pressure. Removes extra water from your body. Lasix (Furosemide) is a very effective water pill and it'll certainly make you go to the bathroom more often.Removes extra water from your body. Aldactone (spironolactone) should be used with other medicines to get rid of excess fluid in your body, especially if you have heart failure.Coming soon.Lowers blood pressure. Bumex (bumetanide) is very good in lowering blood pressure. However, it can make you dehydrated and lower your blood pressure too much.
Reviews & ratings
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Have you used Thalitone (chlorthalidone)?
Worth itNot sureNot worth it
Reviews for Lasix
67%
+33% better vs. chlorthalidone
47%
+53% better vs. chlorthalidone
16%
+16% better vs. chlorthalidone
371 reviews
Have you used Lasix (furosemide)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Aldactone (spironolactone)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Edecrin (ethacrynic acid)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Bumex (bumetanide)?
Worth itNot sureNot worth it
Side effects
chlorthalidoneLasixspironolactoneEdecrinBumex

The chlorthalidone FDA package insert doesn’t have numbers about how common side effects are.

More about chlorthalidone side effects »

The Lasix FDA package insert doesn’t have numbers about how common side effects are.

More about Lasix side effects »

The spironolactone FDA package insert doesn’t have numbers about how common side effects are.

More about spironolactone side effects »

We haven’t found good data for Edecrin side effects.

FDA side effect reports for Edecrin »
  • High uric acid in blood 18%
  • Low potassium 15%
  • High blood sugar 7%
More Bumex side effects »
How it works
chlorthalidoneLasixspironolactoneEdecrinBumex
Thalitone (chlorthalidone) is a thiazide-like diuretic (water pill) that makes you urinate more. It works in the kidneys to remove extra water and certain electrolytes, while lowering blood pressure and reducing swelling.Lasix (Furosemide) is a loop diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Aldactone (spironolactone) is a potassium-sparing diuretic that blocks aldosterone (a hormone) and helps the kidney get rid of excess fluids in your body.Coming soon.Bumex (bumetanide) is a water pill. It prevents the kidneys from absorbing salts, so your body gets rid of more water when you urinate. This lowers blood pressure and decreases swelling.
Type of medication
chlorthalidoneLasixspironolactoneEdecrinBumex
Prescription onlyPrescription onlyPrescription onlyPrescription only
Available as
chlorthalidoneLasixspironolactoneEdecrinBumex
  • Pill
  • Pill
  • Liquid
  • Pill
  • Pill
  • Pill
  • Injection
Used for
chlorthalidoneLasixspironolactoneEdecrinBumex
  • Edema
Risk factors for serious side effects
chlorthalidoneLasixspironolactoneEdecrinBumex
  • History of gout
  • History of diabetes
  • History of kidney disease
  • History of acute kidney failure
  • History of azotemia
Detailed Thalitone (chlorthalidone) risks & warnings »
  • Current electrolyte imbalance
  • History of sulfa allergies
  • Current kidney problems
  • Dose too high
  • Low blood protein
Detailed Lasix (furosemide) risks & warnings »
  • Taking with alcohol
  • Taking other medicines that lower your blood pressure
  • Current kidney problems
  • Taking other medicines that increase potassium
  • Use of salt substitutes
Detailed Aldactone (spironolactone) risks & warnings »
    Coming soon.
    • Age 65 or older
    • Having severe diarrhea
    • History of sulfa allergy
    • Kidney disease
    • High dose of Bumex (bumetanide)
    Detailed Bumex (bumetanide) risks & warnings »
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Food
    chlorthalidoneLasixspironolactoneEdecrinBumex
    No food related info.No food related info.No food related info.No food related info.
    • You can take Bumex (bumetanide) with or without food.
    Kidneys and liver
    chlorthalidoneLasixspironolactoneEdecrinBumex
    • Thalitone (chlorthalidone) works on the kidneys to help increase the amount of fluids removed from the body. This also causes a loss of electrolytes. Your doctor will perform routine blood tests to monitor your electrolyte levels.
    • Thalitone (chlorthalidone) can increase the kidney's retention of uric acid, which can increase your risk of gouty attacks. Let your doctor know if you have a history of gout.
    • Thalitone (chlorthalidone) works on the kidneys. For people with a history of kidney problems, this can put more pressure on your kidneys and make it harder for them to work. Let your doctor know if you have a history of kidney disease.
    • Requires routine blood tests to check your kidney function.
    • Requires routine blood tests to check kidney function.
    • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
    No kidneys and liver related info.
    • Bumex (bumetanide) works on the kidneys to make more urine. If you have kidney problems or have trouble urinating, talk to your doctor to see if this Bumex (bumetanide) is safe to take.
    Pain
    chlorthalidoneLasixspironolactoneEdecrinBumex
    No pain related info.No pain related info.
    • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
    No pain related info.No pain related info.
    Upsides and benefits
    chlorthalidoneLasixspironolactoneEdecrinBumex
    • Does a good job getting rid of extra fluids in your body by making you urinate more.
    • A good blood pressure treatment for people who haven't responded well to other thiazide diuretics. Works especially well for people of African descent.
    • Lowers the risk of heart attack and stroke.
    • Good option if you have high blood pressure and heart failure.
    • Can be good for patients with osteoporosis since it raises the body's level of calcium.
    • A strong diuretic (water pill) that works well to get rid of extra fluids in your body through urination.
    • Lowers your blood pressure and your risk of heart attack and stroke.
    • Works better than thiazide diuretics (like Hydrochlorothiazide) at removing harmful levels of certain electrolytes, such as potassium.
    • Okay to take if you have kidney problems.
    • Has a low risk of causing muscle problems from low potassium levels in your blood.
    • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
    • Can lower blood pressure.
    • Reduces the risk of death in people with heart failure.
    Coming soon
    • Available in generic.
    • Much stronger than other water pills.
    Downsides and risks
    chlorthalidoneLasixspironolactoneEdecrinBumex
    • Makes you urinate more often.
    • Doesn't work well in people with severe kidney problems.
    • Since Thalitone (chlorthalidone) works longer in the body than other thiazide diuretics, it has a higher chance of causing electrolyte changes.
    • Thalitone (chlorthalidone) can lead to more gouty attacks in people with gout.
    • Don't use this if you have a sulfa allergy.
    • Makes you urinate very frequently.
    • Can cause low levels of important electrolytes, such as potassium.
    • Aldactone (spironolactone) doesn't work well on its own. It should be used with another drug to help get rid of excess fluids.
    • Has many possible side effects, especially when higher doses are used.
    • Can increase the risk of tumor growth.
    • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
    Coming soon
    • People taking Bumex (bumetanide) might urinate more often.
    • Bumex (bumetanide) can cause dehydration and loss of salts in your body.
    • People with allergies to sulfa-containing medicines should not take Bumex (bumetanide).
    • Blood tests should be done regularly to check your potassium and other salts.
    Tips from our pharmacists for people taking the medication
    chlorthalidoneLasixspironolactoneEdecrinBumex
    • Take Thalitone (chlorthalidone) in the morning with a meal. It starts working in two hours, so don't take it at night; otherwise you'll go to the bathroom more overnight.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, tiredness, or muscle weakness that doesn't go away.
    • Requires routine blood tests to check your kidney function.
    • Your skin will be more sensitive to the sun while taking this, so don't forget to use sunscreen.
    • Starts working in 30 minutes.
    • Makes you urinate more often, so avoid taking it at bedtime.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
    • Requires routine blood tests to check kidney function.
    • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how the medicine affects you.
    • Don't use supplements or salt substitutes that are high in potassium.
    • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
    • Tell your doctor about any muscle weakness, skin changes, and red or black tarry stool.
    • You will urinate more often within 2 to 3 days, and will have lower blood pressure in 2 to 3 weeks.
    Coming soon
    • Because Bumex (bumetanide) makes you urinate more often, avoid taking it close to bedtime.
    • Bumex (bumetanide) can make make you dizzy. If you are sitting down, stand up slowly.
    • Check your blood pressure regularly.
    • You can take Bumex (bumetanide) with or without food.
    Learn more
    More about chlorthalidoneSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Thalitone (chlorthalidone)?
    Worth itNot sureNot worth it
    More about LasixSide effectsReviews & ratingsFDA package insert
    Have you used Lasix (furosemide)?
    Worth itNot sureNot worth it
    More about spironolactoneSide effectsFDA package insert
    Have you used Aldactone (spironolactone)?
    Worth itNot sureNot worth it
    More about EdecrinSide effectsFDA package insert
    Have you used Edecrin (ethacrynic acid)?
    Worth itNot sureNot worth it
    More about BumexSide effectsReviews & ratingsFDA package insert
    Have you used Bumex (bumetanide)?
    Worth itNot sureNot worth it