Prescription onlyLower-cost generic available



  • Pill
  • Dissolving tablet
  • Liquid
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Treats allergy symptoms.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Clarinex (Desloratadine) is a good option for once-daily allergy relief. It doesn't make you feel sleepy, but you need a prescription.

  • Relieves allergy symptoms like sneezing, runny nose, congestion, hives, or itchy skin.
  • Preferred for older people since it causes little to no drowsiness compared to other antihistamines like Diphenhydramine (Benadryl).
  • Works faster than other non-drowsy antihistamines like Loratadine (Claritin).
  • Side effects are rare and usually mild.
  • Available as a liquid or fast-dissolving tablet for people who don't like swallowing pills.
  • May not work as fast as the other antihistamines that make you sleepy (like Benadryl).
  • Not a good medication for pregnant women to take.

Save on your next Clarinex (Desloratadine) prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.

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Side effects for Clarinex (Desloratadine)

From clinical trials of Clarinex / Allergies (1 mg) 

  • Ear, nose, or throat infectionEar, nose, or throat infection21% for Desloratadine vs.13% for placebo
  • DiarrheaDiarrhea20% for Desloratadine vs.8% for placebo
  • FeverFever12% for Desloratadine vs.2% for placebo
  • IrritabilityIrritability12% for Desloratadine vs.11% for placebo
  • CoughingCoughing11% for Desloratadine vs.10% for placebo
  • DrowsinessDrowsiness9% for Desloratadine vs.8% for placebo
  • BronchitisBronchitis6% for Desloratadine vs.0% for placebo
  • Middle ear inflammationMiddle ear inflammation6% for Desloratadine vs.2% for placebo
  • VomitingVomiting6% for Desloratadine vs.3% for placebo
  • Loss of appetiteLoss of appetite5% for Desloratadine vs.2% for placebo

Pharmacist tips

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  • Starts working in an hour.
  • Take it once a day when needed.
  • Works the best if used regularly during allergy season.
  • Can give you a headache or diarrhea, but it rarely causes drowsiness or dizziness.

Tips from pharmacists and people taking Clarinex (Desloratadine)

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The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits