Climara

(estradiol patch)

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Treats low estrogen, relieves menopause symptoms, and lowers your risk of osteoporosis.

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Our bottom line

Climara (estradiol patch) is a treatment for low estrogen that is used only once weekly, and it may have fewer side effects than oral estrogen pills.

Quick facts about Climara
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (estradiol patch)
Prices and discounts
Lowest price for 1 4-once-weekly-patches-of-0.05mg-day cartons
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$121.93

Upsides

  • Climara (estradiol patch) replaces estrogen to your whole body and relieves many symptoms due to low estrogen, like hot flashes and vaginal dryness.
  • The patch is good for people who don't want to or can't take daily pills.
  • Climara (estradiol patch) is available as a generic product, which lowers the cost.
  • By using a patch instead of a pill, there's a lower risk of side effects such as blood clots and stroke since lower amounts of estrogen are used in patches.
  • Lowers your risk of fractures by keeping your bones healthy.

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What to expect from Climara, on one page

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Downsides

  • The patch can fall off, especially if you like to regularly swim, take baths or use saunas or steamrooms.
  • Increases your risk of uterine and breast cancer.
  • If you have your uterus, you have to use the Climara (estradiol patch) with another hormone called progestin to lower your risk of uterine cancer.
  • Can worsen other health conditions, like high cholesterol, asthma, diabetes, fluid retention, underactive thyroid and migraines.
  • If you're only having vaginal dryness or inflammation and not hot flashes, it's better to use creams that you can apply to the affected area instead of Climara (estradiol patch).

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Get our free fact sheet

What to expect from Climara, on one page

Download Fact Sheet
Prices and discounts
Lowest price for 1 4-once-weekly-patches-of-0.05mg-day cartons
Determining your location...
$121.93
How it works

The Climara (estradiol patch) replaces estrogen that your body loses during and after menopause. Higher levels of estrogen help relieve symptoms of menopause and prevent bone loss.

Quick facts about Climara
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (estradiol patch)

Used for

  • Hot flashes and night sweats
  • Vaginal dryness and inflammation
  • Low estrogen

Dosage forms

  • Patch
Tried Climara? Write a review!

What to expect when you take Climara (estradiol patch) for Menopause symptoms

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Side effect rates for Climara (estradiol patch)

From 266 clinical trials of Climara when taken for postmenopausal estrogen replacement (0.1 mg/day)
  • Breast pain
  • Lung infection
  • Stomach pain
  • Headache
  • Pain
  • Swelling of arms and legs
  • Back pain
  • Depression
  • Gas
  • White or yellow vaginal discharge

Risks and Warnings for Climara (estradiol patch)

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    • Higher risk if:
    • Using estrogen for more than one year

    If you're taking Climara (estradiol patch) and have your uterus, you might have a higher risk of having endometrial cancer. Vaginal bleeding after menopause can be a warning sign, so let your doctor know if you notice any unusual bleeding. Using medicines like Climara (estradiol patch) for more than a year can increase your risk. Talk to your doctor about other medicines you can take with Climara (estradiol patch) to protect yourself from cancer if you are worried.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Climara (estradiol patch)

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  • Can cause nausea, dizziness, bloating, and breast tenderness. Tell your doctor right away if you have unusual vaginal bleeding.