Climara Pro

(estradiol / levonorgestrel patch)

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Relieves hot flashes and lowers your risk of osteoporosis.

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Our bottom line

The Climara Pro (estradiol / levonorgestrel patch) is effective at treating menopause symptoms, and it can be a good choice for women who need estrogen/progestin combination medications but prefer to use a patch once a week instead of pills every day.

Quick facts about Climara Pro
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available
Prices and discounts
Lowest price for 1 4-patches-of-0.045mg-0.015mg packages
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$194.25

Upsides

  • Once-a-week patch. Good for people who don't want to take daily pills.
  • Replaces estrogen in your body and relieves multiple symptoms from low estrogen, such as hot flashes and vaginal dryness.
  • Fewer side effects than pills since patches contain lower amounts of hormones.
  • Good for women with an intact uterus. The progestin in the patch protects against the risk of cancer in the uterus.
  • The Climara Pro (estradiol / levonorgestrel patch) patch has a lower risk of causing blood clots and stroke compared to other forms containing the same medicines.

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What to expect from Climara Pro, on one page

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Downsides

  • More potential side effects than medications with one ingredient since Climara Pro (estradiol / levonorgestrel patch) exposes your whole body to two hormones.
  • Increases your risk of developing blood clots and stroke.
  • You may get irregular bleeding and spotting that can last a few months to a year.
  • The patch can fall off, especially if you like to regularly swim, take baths, or use saunas.
  • Can be expensive since it's only available as a brand name product.

Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Climara Pro, on one page

Download Fact Sheet
Prices and discounts
Lowest price for 1 4-patches-of-0.045mg-0.015mg packages
Determining your location...
$194.25
How it works

Climara Pro (estradiol / levonorgestrel patch) is an estrogen/progestin combination patch that works to balance hormone changes in your body during and after menopause. Estrogen reduces hot flashes, reduces night sweats, and prevents bone loss. Progestin protects the uterus from damage.

Quick facts about Climara Pro
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Hot flashes and night sweats
  • Prevention of postmenopausal osteoporosis

Dosage forms

  • Patch
Tried Climara Pro? Write a review!

What to expect when you take Climara Pro (estradiol / levonorgestrel patch) for Menopause symptoms

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Side effect rates for Climara Pro (estradiol / levonorgestrel patch)

From 212 clinical trials of Climara Pro when taken for postmenopausal hormone replacement (0.045/0.015 mg)
  • Skin irritation
  • Vaginal bleeding
  • Breast pain
  • Lung infection
  • Back pain
  • Depression
  • Flu like symptoms
  • Pain
  • Headache
  • Stomach pain

Risks and Warnings for Climara Pro (estradiol / levonorgestrel patch)

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    • Higher risk if:
    • Using estrogen for more than one year

    If you're taking Climara Pro (estradiol / levonorgestrel patch) and have your uterus, you might have a higher risk of having endometrial cancer. Vaginal bleeding after menopause can be a warning sign, so let your doctor know if you notice any unusual bleeding. Using medicines like Climara Pro (estradiol / levonorgestrel patch) for more than a year can increase your risk. Talk to your doctor about other medicines you can take with Climara Pro (estradiol / levonorgestrel patch) to protect yourself from cancer if you are worried.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Climara Pro (estradiol / levonorgestrel patch)

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  • Can cause nausea, dizziness, bloating, and breast tenderness. Tell your doctor right away if you have unusual vaginal bleeding.