Prescription onlyLower-cost generic available

Clomid

(Clomiphene)

  • Pill
  • Female infertility
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Induces ovulation.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Clomid (Clomiphene) works well to induce ovulation in women who have already tried other options. Be prepared for a somewhat complicated dosing schedule.

  • It's taken by mouth and not given as an injection.
  • Clomid (Clomiphene) is effective in women who have polycystic ovary syndrome.
  • It doesn't affect pituitary, adrenal, or thyroid functions.
  • Treatment can be repeated if it doesn't work the first time.
  • Clomid (Clomiphene) isn't a first-choice therapy. Other options need to be tried before starting this drug.
  • A pelvic exam and pregnancy test are necessary prior to each course of Clomid (Clomiphene).
  • You can't use Clomid (Clomiphene) if you currently have liver problems.
  • Clomid (Clomiphene) isn't safe for women who have ovarian cysts or enlarged ovaries (aside from polycystic ovary syndrome).

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Side effects for Clomid (Clomiphene)

From clinical trials of Clomid / Female infertility ( 8029)

  • Ovarian enlargementOvarian enlargement14% for Clomid vs.0% for placebo
  • Hot flashesHot flashes10% for Clomid vs.0% for placebo
  • Abdominal-pelvic discomfort/distention/bloatingAbdominal-pelvic discomfort/distention/bloating6% for Clomid vs.0% for placebo
  • Nausea and vomitingNausea and vomiting2% for Clomid vs.0% for placebo
  • Breast discomfortBreast discomfort2% for Clomid vs.0% for placebo
  • Visual symptomsVisual symptoms2% for Clomid vs.0% for placebo
  • HeadacheHeadache1% for Clomid vs.0% for placebo
  • Abnormal uterine bleedingAbnormal uterine bleeding1% for Clomid vs.0% for placebo

What to expect when you take Clomid (Clomiphene)

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Tips from our pharmacists
  • Be ready for a complicated dosing schedule. It's very important to take Clomid (Clomiphene) exactly as your doctor prescribed.
  • Ovulation usually occurs between 5 to 10 days after taking Clomid (Clomiphene), so make sure to have intercourse when you're ovulating.
  • Basal body temperature graphs or other tests can help you determine if you've ovulated.
  • Clomid (Clomiphene) can't be used in pregnant women, so it's important to work closely with your doctor throughout your treatment.

Risks and Warnings for Clomid (Clomiphene)

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  • Clomid (Clomiphene) therapy can't be used in women who have liver disease or a history of liver damage. Talk to your doctor about other options that can work for you.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Clomid (Clomiphene)

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The FDA category for this medication is X. It is advised that you: Unsafe
Pregnancy
Weight gain or loss
  • Risks from our pharmacists
  • Ovarian enlargement can occur during or shortly after taking Clomid (Clomiphene). To lower this risk, tell your doctor about any stomach or pelvic pain, weight gain, discomfort, or distention after taking the medication.