Prescription onlyLower-cost generic available

Clozaril

(Clozapine)

  • Pill
  • Dissolving tablet
  • Liquid
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Helps control your thoughts and actions.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Clozaril (Clozapine) treats schizophrenia when other drugs haven't worked, but you'll have to get blood work done regularly and might gain weight.

  • Clinical studies show that Clozaril (Clozapine) is effective in treating schizophrenia when other medications have failed.
  • Has the lowest risk of causing movement problems when compared to other antipsychotic medicines.
  • Clozaril (Clozapine) is available as a normal tablet and as a mint-flavored tablet that dissolves on the tongue without water.
  • Available as a generic, which is cheaper.
  • You need to get blood work done every time you can get a prescription filled for Clozaril (Clozapine).
  • You can only get Clozaril (Clozapine) at certain pharmacies that are registered to provide it.
  • If you don't get Clozaril (Clozapine) within 7 days of it being ready at the pharmacy, then you have to get blood work done again and get a new prescription from your doctor.
  • You need to limit the amount of alcohol you drink while on Clozaril (Clozapine).

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Side effects for Clozaril (Clozapine)

From clinical trials of Clozaril / Schizophrenia ( 842)

  • Drowsiness/sedationDrowsiness/sedation39% for Clozapine vs.0% for placebo
  • SalivationSalivation31% for Clozapine vs.0% for placebo
  • Abnormally fast heart beatAbnormally fast heart beat25% for Clozapine vs.0% for placebo
  • Dizziness/vertigoDizziness/vertigo19% for Clozapine vs.0% for placebo
  • ConstipationConstipation14% for Clozapine vs.0% for placebo
  • Low blood pressureLow blood pressure9% for Clozapine vs.0% for placebo
  • HeadacheHeadache7% for Clozapine vs.0% for placebo
  • Dry mouthDry mouth6% for Clozapine vs.0% for placebo
  • SweatingSweating6% for Clozapine vs.0% for placebo
  • FaintingFainting6% for Clozapine vs.0% for placebo

What to expect when you take Clozaril (Clozapine)

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Tips from our pharmacists
  • Take Clozaril (Clozapine) exactly as prescribed and don't stop taking it without talking to your doctor.
  • Can cause dizziness or drowsiness. Avoid alcohol and be careful when changing positions or doing anything that requires your full attention until you know how it affects you.
  • Blood tests are needed before you start this medicine and before every refill. You need to pick up the medicine within 7 days of your blood tests.
  • Can affect your weight, cholesterol, and blood sugar control.

Risks and Warnings for Clozaril (Clozapine)

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  • People on Clozaril (Clozapine) can lose white blood cells. This makes it harder for the body to fight off infections, and people have died from it. You need to have blood work done every time before your doctor can write a new or refill prescription for Clozaril (Clozapine) to make sure you're not at risk.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Clozaril (Clozapine)

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The FDA category for this medication is B. It is advised that you: Probably safe
Pregnancy
Alcohol
  • Upsides and downsides from our pharmacists
  • You need to limit the amount of alcohol you drink while on Clozaril (Clozapine).
  • Tips from our pharmacists
  • Can cause dizziness or drowsiness. Avoid alcohol and be careful when changing positions or doing anything that requires your full attention until you know how it affects you.
  • Risks from our pharmacists
  • People on Clozaril (Clozapine) have reported having seizures. The risk gets higher with increasing dose or if you have conditions that make you more likely to have seizures, like alcohol abuse. If you're on medications because you've had seizures in the past, talk to your doctor to see if the medications need to be adjusted.
Sleep
  • Tips from our pharmacists
  • Can cause dizziness or drowsiness. Avoid alcohol and be careful when changing positions or doing anything that requires your full attention until you know how it affects you.
  • Go to bed early, so you could wake up refreshed and not sleep till noon.
    Age: 35
    Gender: Man
    Taken for: Schizophrenia
Weight gain or loss
  • Tips from our pharmacists
  • Can affect your weight, cholesterol, and blood sugar control.
  • Risks from our pharmacists
  • People on Clozaril (Clozapine) have reported weight gain. This is common. If this bothers you, talk to your doctor about what you can do to stop this from happening.