Prescription onlyLower-cost generic availableClass: Mental health

Clozaril

(clozapine)

Prescription onlyLower-cost generic availableClass: Mental health
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Helps control your thoughts and actions.

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Our bottom line

Clozaril (Clozapine) treats schizophrenia when other drugs haven't worked, but you'll have to get blood work done regularly and might gain weight.

Price and discounts
Prices and coupon for 90 (100mg) tablets of clozapine

Upsides

  • Clinical studies show that Clozaril (Clozapine) is effective in treating schizophrenia when other medications have failed.
  • Has the lowest risk of causing movement problems when compared to other antipsychotic medicines.
  • Clozaril (Clozapine) is available as a normal tablet and as a mint-flavored tablet that dissolves on the tongue without water.
  • Available as a generic, which is cheaper.

Downsides

  • You need to get blood work done every time you can get a prescription filled for Clozaril (Clozapine).
  • You can only get Clozaril (Clozapine) at certain pharmacies that are registered to provide it.
  • If you don't get Clozaril (Clozapine) within 7 days of it being ready at the pharmacy, then you have to get blood work done again and get a new prescription from your doctor.
  • You need to limit the amount of alcohol you drink while on Clozaril (Clozapine).
How it works

Clozaril (Clozapine) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.

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Side effect rates for Clozaril (clozapine)

842 From clinical trials of Clozaril / Schizophrenia
  • Drowsiness/sedation
  • Salivation
  • Abnormally fast heart beat
  • Dizziness/vertigo
  • Constipation
  • Low blood pressure
  • Headache
  • Dry mouth
  • Sweating
  • Fainting

Risks and Warnings for Clozaril (clozapine)

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  • People on Clozaril (Clozapine) can lose white blood cells. This makes it harder for the body to fight off infections, and people have died from it. You need to have blood work done every time before your doctor can write a new or refill prescription for Clozaril (Clozapine) to make sure you're not at risk.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Clozaril (clozapine)

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Pregnancy
Alcohol
  • You need to limit the amount of alcohol you drink while on Clozaril (Clozapine).
  • Can cause dizziness or drowsiness. Avoid alcohol and be careful when changing positions or doing anything that requires your full attention until you know how it affects you.
Sleep
  • Can cause dizziness or drowsiness. Avoid alcohol and be careful when changing positions or doing anything that requires your full attention until you know how it affects you.
Weight
  • Can affect your weight, cholesterol, and blood sugar control.
  • People on Clozaril (Clozapine) have reported weight gain. This is common. If this bothers you, talk to your doctor about what you can do to stop this from happening.