Prescription onlyNo lower cost generic available

Colcrys

(Colchicine)

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Prevents and treats gout.

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Prescription onlyNo lower cost generic available

Our pharmacists’ bottom line

Colcrys (Colchicine) is a second-choice treatment for gout attacks. Be careful how much you use since it causes a lot of side effects.

  • Is an antigout medication that has anti-inflammatory properties to help treat sudden gout attacks.
  • Lowers the risk of sudden gout attacks when taken as prescribed to prevent gout attacks.
  • Also treats Familial Mediterranean Fever.
  • Doesn't work as well as nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids to treat gout attacks.
  • Taking too much can cause serious side effects.
  • Doses needs to be adjusted if you have kidney or liver problems.
  • Doesn't have the ability to ease or treat pain.

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Side effects for Colcrys (Colchicine)

From clinical trials of Colcrys / Gout ( 133)

  • Gastrointestinal disordersGastrointestinal disorders26% for Colchicine vs.20% for placebo
  • DiarrheaDiarrhea23% for Colchicine vs.0% for placebo
  • DiarrheaDiarrhea23% for Colchicine vs.14% for placebo
  • NauseaNausea4% for Colchicine vs.5% for placebo
  • Metabolic and nutrition disordersMetabolic and nutrition disorders4% for Colchicine vs.3% for placebo
  • GoutGout4% for Colchicine vs.2% for placebo
  • Throat painThroat pain3% for Colchicine vs.0% for placebo
  • Throat painThroat pain3% for Colchicine vs.0% for placebo
  • Respiratory thoracic mediastinal disordersRespiratory thoracic mediastinal disorders3% for Colchicine vs.0% for placebo
  • Nervous system disordersNervous system disorders1% for Colchicine vs.3% for placebo

Manufacturers don’t say how common these side effects are

  • Abdominal discomfort

What to expect when you take Colcrys (Colchicine)

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Tips from our pharmacists
  • Take it with or without food.
  • At the first sign of a gout attack, take two tablets. Don't take more than three tablets a day in order to avoid serious side effects.
  • Wait at least 3 days before another using Colcrys (Colchicine) again.
  • Almost all people experience some nausea, vomiting, or diarrhea after taking Colcrys (Colchicine).
  • Let your doctor know of any serious nausea, vomiting, diarrhea, or if you have tingling in your fingers or toes.

Risks and Warnings for Colcrys (Colchicine)

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  • Colcrys (Colchicine) can lower your body's ability to make new blood cells. This can happen even when you're using the appropriate doses. Let your doctor know if you have frequent bleeding/bruising, fevers, or always feel tired.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Colcrys (Colchicine)

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The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits
Pregnancy
Food
  • Tips from our pharmacists
  • Take it with or without food.
Kidneys & liver
  • Upsides and downsides from our pharmacists
  • Doses needs to be adjusted if you have kidney or liver problems.
  • Risks from our pharmacists
  • People on Colcrys (Colchicine) have reported muscle pain which can lead to muscle and kidney damage. This has been very rare. Talk to your doctor if you develop sudden muscle pain, weakness, or a fever and you don't know why.