Treats low estrogen and relieves menopause symptoms.
Our bottom line
Combipatch (Estradiol / Norethindrone Patch) is effective at treating menopause symptoms, and it can be a good choice for women who need estrogen/progestin combo medications, but prefer to use a patch every twice a week instead of pills every day.
- (1) 8 patches of 0.05mg/0.14mg package
- Cost for (1) 8 patches of 0.05mg/0.14mg package of Combipatch (Estradiol / Norethindrone Patch) at pharmacies
- Twice-a-week patch. Good for people who don't want to take daily pills.
- Combipatch (Estradiol / Norethindrone Patch) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen (hot flashes, vaginal dryness).
- Fewer side effects than pills since patches contain lower amounts of hormones.
- Good for women with an intact uterus. The norethindrone (a progestin) protects against the risk of cancer in the uterus caused by estrogen treatment.
- More potential side effects than single-ingredient medications since it exposes your whole body to two hormones, estrogen and norethindrone (a progestin).
- Increases your risk of developing blood clots and stroke.
- You may get irregular bleeding and spotting that can last a few months to a year.
- Patch can fall off.
- Can be expensive since it's only available as a brand name product.
Side effect rates for Combipatch (Estradiol / Norethindrone Patch)
- Breast pain
- Menstrual cramps
- Application site reaction
- Inflammation inside the nose
- Menstrual disorder
- Back pain
- Flu syndrome
Risks and Warnings for Combipatch (Estradiol / Norethindrone Patch)Skip risks section. Skip to common concerns section.
- Higher risk if:
- › Using estrogen for more than one year
Vaginal bleeding after menopause can be a warning sign of uterus (endometrial) cancer, so let your doctor know if you notice any unusual bleeding. When estrogen is prescribed to women after menopause who still have a uterus, progestin should be used with it to lower the risk of cancer. Low-dose vaginal estrogen products are often a better choice than oral pills for women 65 years or older who have vaginal symptoms.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.
Common concerns from people taking Combipatch (Estradiol / Norethindrone Patch)Final section. Do you want to return to drug navigation?
- Can cause nausea, dizziness, bloating, and breast tenderness.
- Combipatch (Estradiol / Norethindrone Patch) is a mixture of estrogen and progestin. It could cause a higher risk of ovarian cancer, especially if you have a family history of it. Your doctor can help you weigh the risks versus the benefits of this medication.