Prescription onlyLower-cost generic available


(Ipratropium / Albuterol)

  • Inhaler
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Makes it easier to breathe.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Combivent (Ipratropium / Albuterol) is good for people who need 2 medicines to relieve their COPD symptoms, but you need to be okay with taking it four times a day.

Worth itNot sureNope
Worked WellSomewhatDidn't work
No hassleSomewhatHuge hassle
Worth it
Men: 63%
Women: 63%
Works well
Men: 37%
Women: 37%
It's a hassle
Men: 13%
Women: 13%
  • 2-in-1 medicine that opens airways and makes it easier to breathe. Medicines are more effective together than alone.
  • Effectively relieves COPD and asthma symptoms.
  • Respimat formulation has a clear display for dosing, doesn't require shaking, and only needs one inhalation per dose.
  • You have to use Combivent four times a day.
  • Can make your heart race.
  • Can make symptoms of enlarged prostate or urinary blockage worse.
  • Can worsen a certain type of glaucoma.

Save on your next Combivent (Ipratropium / Albuterol) prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.

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Side effects for Combivent (Ipratropium / Albuterol)

From clinical trials of Combivent / COPD (Ipratropium Bromide 36 mcg/Albuterol Sulfate 206 mcg QI) ( 358)

  • BronchitisBronchitis12% for Combivent vs.0% for placebo
  • Ear, nose, or throat infectionEar, nose, or throat infection11% for Combivent vs.0% for placebo
  • HeadacheHeadache6% for Combivent vs.0% for placebo
  • Shortness of breathShortness of breath5% for Combivent vs.0% for placebo
  • CoughingCoughing4% for Combivent vs.0% for placebo
  • PainPain3% for Combivent vs.0% for placebo
  • Respiratory disordersRespiratory disorders3% for Combivent vs.0% for placebo
  • NauseaNausea2% for Combivent vs.0% for placebo
  • Sore throatSore throat2% for Combivent vs.0% for placebo
  • Sinus inflammationSinus inflammation2% for Combivent vs.0% for placebo

Manufacturers don’t say how common these side effects are

  • Bronchospasm
  • Chest pain
  • Deep skin swelling
  • Hives
  • Itching
  • Laryngospasm
  • Rash
  • Serious allergic reaction

Pharmacist tips

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  • Starts working in 15 to 30 minutes, and lasts about 4 to 6 hours.
  • Make sure to read the instructions about how to set up your first dose.
  • Clean the mouthpiece with a damp cloth once a week.
  • The inhaler shows you how much medication you have left so you can plan ahead for refills.
  • Don't take it more often or change your dose without talking to your doctor first.
  • Tell your doctor if the medication stops working or if your symptoms get worse.
  • One type of inhaler contains soya lecithin, so don't use if you have soybean, peanut, or allergies to atropine.

Risks and Warnings for Combivent (Ipratropium / Albuterol)

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  • There are reports of difficulty breathing (bronchospasm) after inhaling Combivent (Ipratropium / Albuterol). Call 911 or your doctor right away if a fast-acting (rescue) inhaler does not stop the attack. Talk to you doctor if your symptoms worsen while taking Combivent (Ipratropium / Albuterol), you may need to discuss other medication options that will treat your condition.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Combivent (Ipratropium / Albuterol)

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The FDA category for this medication is C. It is advised that you: Weigh risks vs. benefits
  • Risks from our pharmacists
  • There are reports of severe allergic reactions in people taking Combivent (Ipratropium / Albuterol) aerosol inhaler who have allergies to soybean or peanuts. This is because the aerosol contains soya lecithin. Call 911 or your doctor right away if you develop severe rash, itching, swelling or difficulty breathing while taking Combivent (Ipratropium / Albuterol). Talk to your doctor about other medication choices to treat your COPD if you know you have food allergies to soybean and/or peanuts.
  • Risks from our pharmacists
  • One of the medications in Combivent (Ipratropium / Albuterol) may increase blood pressure and heart rate, especially if you already have these conditions. Tell your doctor if you notice a tremor, rapid heartbeat, get dizzy or have difficulty sleeping while taking Combivent (Ipratropium / Albuterol), you may need to change or stop this medication.