Combivir

(lamivudine / zidovudine)

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Treats HIV infection

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While Combivir (lamivudine / zidovudine) isn't one of the first choices for treating HIV, it can still be an option if other HIV medications aren't working well for you.

Quick facts about Combivir
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (lamivudine / zidovudine)
Prices and discounts
Lowest price for 60 150mg-300mg tablets
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$105.14

Upsides

  • Combivir (lamivudine / zidovudine) can be taken with or without food.
  • Combivir (lamivudine / zidovudine) can be taken by children and adolescents weighing 30kg (66lbs) or more.
  • Available in generic.

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What to expect from Combivir, on one page

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Downsides

  • Combivir (lamivudine / zidovudine) needs to be taken twice daily.
  • Combivir (lamivudine / zidovudine) may cause serious blood, muscle, and liver problems.
  • Combivir (lamivudine / zidovudine) is not recommended if you have kidney damage.
  • Combivir (lamivudine / zidovudine) can cause a lot of side effects, including nausea, vomiting, loss of appetite, headache, and malaise.

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Get our free fact sheet

What to expect from Combivir, on one page

Download Fact Sheet
Prices and discounts
Lowest price for 60 150mg-300mg tablets
Determining your location...
$105.14
How it works

Combivir (lamivudine / zidovudine) is a combination tablet that contains two medicines that treat HIV infection by preventing the virus from attacking your immune cells and multiplying.

Quick facts about Combivir
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (lamivudine / zidovudine)

Dosage forms

  • Pill
Tried Combivir? Write a review!

What to expect when you take Combivir (lamivudine / zidovudine) for HIV infection

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Side effect rates for Combivir (lamivudine / zidovudine)

From 251 clinical trials of Combivir when taken for hiv treatment
  • Headache
  • Nausea
  • Malaise and fatigue
  • Nose-related problems
  • Diarrhea
  • Cough
  • Nausea and vomiting
  • Nerve problems
  • Bone pain
  • Insomnia and other sleep disorders

Risks and Warnings for Combivir (lamivudine / zidovudine)

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    • Higher risk if:
    • Advanced HIV
    • Anemia
    • Neutropenia

    Combivir (lamivudine / zidovudine) can damage your bone marrow. This can affect how your body fights off infections or makes new blood cells. Your doctor will check your blood regularly, and might have to change your doses if you start having problems.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Combivir (lamivudine / zidovudine)

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Food
  • Combivir (lamivudine / zidovudine) can be taken with or without food.
Kidneys and liver
  • Severe worsening of Hepatitis B has been seen in patients who have stopped taking Combivir (lamivudine / zidovudine). Your doctor will check your liver regularly. Let your doctor know right away if you have any signs of liver problems like jaundice, dark urine, or yellowing of eyes. Don't stop taking Combivir (lamivudine / zidovudine) until you've talked to your doctor first.
  • Combivir (lamivudine / zidovudine) is not recommended if you have kidney damage.