Prescription onlyLower-cost generic availableClass: Gastrointestinal

Compro

(prochlorperazine)

Prescription onlyLower-cost generic availableClass: Gastrointestinal
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Helps you feel less queasy.

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Our bottom line

Compro (Prochlorperazine) can be used to treat severe nausea and vomiting and can be taken orally or rectally, but get ready for a nap.

Price and discounts
Prices and coupon for 30 (10mg) tablets of prochlorperazine

Upsides

  • Available in generic, so it's cheap.
  • Can be taken by mouth, as a shot, or rectally.
  • Can take anywhere from 10 minutes (by shot) to 60 minutes (rectally) to start working.

Downsides

  • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
  • Can't be used by people over 65 because they can be more affected by the side effects.
  • It can make you more likely to get heatstroke.
How it works

Compro (Prochlorperazine) is an antiemetic (anti-nausea medicine). It works by blocking signals in the part of your brain that causes vomiting.

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Side effect rates for Compro (prochlorperazine)

Risks and Warnings for Compro (prochlorperazine)

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    • Higher risk if:
    • Over age 65
    • Dementia
    • Taking antipsychotics

    It is not recommended for people with dementia over age 65 who are taking antipsychotic medications to take Compro (Prochlorperazine), as there is an increased risk of death. Your doctor will discuss alternatives.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Compro (prochlorperazine)

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Pregnancy
Alcohol
  • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
  • Don't drink alcohol to avoid intense side effects.
Pain
  • Taking certain medications for pain, allergies, or mood conditions can worsen the side effects of Compro.
Sleep
  • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
  • You'll likely feel very sleepy, sluggish, or less alert after taking Compro. Avoid driving or other tasks that require your focused attention; be safe.