4.0/ 7 average rating with 20 reviewsforCompro

Compro
Alternatives

(Prochlorperazine)

Compro (Prochlorperazine)

Prescription only

Zofran (Ondansetron)

Prescription only
1 of 3 alternatives
Helps you feel less queasy.

Compro (Prochlorperazine) can be used to treat severe nausea and vomiting and can be taken orally or rectally, but get ready for a nap.

Helps you feel less queasy.

Zofran (Ondansetron) works well to prevent nausea and vomiting, and it's available in different forms that you don't have to swallow.

Upsides
  • Available in generic, so it's cheap.
  • Can be taken by mouth, as a shot, or rectally.
  • Can take anywhere from 10 minutes (by shot) to 60 minutes (rectally) to start working.
  • Available in generic.
  • Available in forms that you don't have to swallow (like a tablet or film that dissolves in your mouth) if you're having trouble keeping anything down.
  • Starts working fast (in 30 minutes.
Downsides
  • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
  • Can't be used by people over 65 because they can be more affected by the side effects.
  • It can make you more likely to get heatstroke.
  • Can cause headaches.
  • Can interact with antidepressants.
  • Can only be used to prevent nausea and vomiting, not to treat if it's already happening.
Used for
Dosage forms
  • Pill
  • Suppository
  • Pill
  • Dissolving tablet
  • Liquid
  • Sublingual film
Price
Lowest price near you
$4
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Lowest price near you
$13.13
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Reviews
20 
45%
think this treatment is worth it
35%
think this treatment works well
35%
think this treatment is a hassle

Have you used Compro (Prochlorperazine)?

Leave a review
366 
66%
think this treatment is worth it
51%
think this treatment works well
15%
think this treatment is a hassle

Have you used Zofran (Ondansetron)?

Leave a review
Side effects
The Compro (Prochlorperazine) FDA package insert doesn’t have numbers about how common side effects are.
5possible side effects
  • Headache
    17%
  • Diarrhea
    16%
  • Constipation
    11%
  • Fever
    8%
  • Increased AST and ALT
    5%
See more detailed side effects
Risks and warnings
  • Increased risk of death

    Over age 65

    ...and 2 more risk factors

  • Seizures

    History of seizures

  • Involuntary muscle movements

    Age over 65

  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

See more detailed risks and warnings
  • Heart rhythm problems

    Long QT syndrome

See more detailed risks and warnings