Compro (Prochlorperazine) can be used to treat severe nausea and vomiting and can be taken orally or rectally, but get ready for a nap.
Zofran (Ondansetron) works well to prevent nausea and vomiting, and it's available in different forms that you don't have to swallow.
- Available in generic, so it's cheap.
- Can be taken by mouth, as a shot, or rectally.
- Can take anywhere from 10 minutes (by shot) to 60 minutes (rectally) to start working.
- Available in generic.
- Available in forms that you don't have to swallow (like a tablet or film that dissolves in your mouth) if you're having trouble keeping anything down.
- Starts working fast (in 30 minutes.
- Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
- Can't be used by people over 65 because they can be more affected by the side effects.
- It can make you more likely to get heatstroke.
- Can cause headaches.
- Can interact with antidepressants.
- Can only be used to prevent nausea and vomiting, not to treat if it's already happening.
- Dissolving tablet
- Sublingual film
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- Increased AST and ALT5%
- Increased risk of death
Over age 65
...and 2 more risk factors
History of seizures
- Involuntary muscle movements
Age over 65
- Driving impairment
Taking with alcohol
...and 1 more risk factors
- Heart rhythm problems
Long QT syndrome