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Copaxone Alternatives

(Glatiramer)

  • Injection
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Compare Copaxone (Glatiramer) to alternatives

These medications are comparable to Copaxone (Glatiramer) or used for similar purposes.

Copaxone
(Glatiramer)

Avonex
(Interferon Beta-1A)

Betaseron
(Interferon Beta-1B)

Gilenya
(Fingolimod)

Avonex
(Interferon Beta-1A)

Aubagio
(Teriflunomide)

Lowers the frequency of multiple sclerosis exacerbations. Copaxone (Glatiramer) is an injectable medicine that's effective for relapsing, remitting MS. It has fewer side effects than other meds, but the self-injections are needed frequently.Lowers the frequency of multiple sclerosis exacerbations. Avonex (Interferon Beta-1A) is an injectable medicine effective for relapsing, remitting MS and has manageable side effects and weekly dosing.Lowers the frequency of MS exacerbations. Betaseron (Interferon Beta-1B) is an injectable medicine effective for relapsing, remitting MS with fewer side effects and every other day dosing.Treats relapsing forms of multiple sclerosis. Gilenya (Fingolimod) is an oral medication that has a lot of side effects, but it reduces the number of flare-ups, slows physical changes, and decreases the number of new brain lesions in relapsing MS.Lowers the frequency of multiple sclerosis exacerbations. Avonex (Interferon Beta-1A) is an injectable medicine effective for relapsing, remitting MS and has manageable side effects and weekly dosing.Treats relapsing forms of MS. Aubagio (Teriflunomide) is an oral medicine that effectively reduces the number of flare-ups, slows physical changes, and decreases the number of new brain lesions in relapsing MS. Because it stays in the body for so long, if you have a serious reaction or possible pregnancy you'll need to have it quickly removed with another medicine.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.310344827586207Copaxone
Reviews for Copaxone (Glatiramer)
52%
of people say Copaxone (Glatiramer) is worth it
38%
say it works well
28%
say it's a big hassle
Reviews for Avonex (Interferon Beta-1A)
38%
14% vs. Copaxone (Glatiramer)
25%
13% vs. Copaxone (Glatiramer)
34%
6% vs. Copaxone (Glatiramer)
Reviews for Betaseron (Interferon Beta-1B)
55%
+3% vs. Copaxone (Glatiramer)
45%
+7% vs. Copaxone (Glatiramer)
40%
12% vs. Copaxone (Glatiramer)
Reviews for Gilenya (Fingolimod)
42%
10% vs. Copaxone (Glatiramer)
30%
8% vs. Copaxone (Glatiramer)
30%
2% vs. Copaxone (Glatiramer)
Reviews for Avonex (Interferon Beta-1A)
38%
14% vs. Copaxone (Glatiramer)
25%
13% vs. Copaxone (Glatiramer)
34%
6% vs. Copaxone (Glatiramer)
Reviews for Aubagio (Teriflunomide)
40%
12% vs. Copaxone (Glatiramer)
25%
13% vs. Copaxone (Glatiramer)
35%
7% vs. Copaxone (Glatiramer)
Side effects
CopaxoneAvonexBetaseronGilenyaAvonexAubagio
  • Injection site erythema 33%
  • Infection 27%
  • Injection site pruritus 23%
  • Injection site pain 20%
  • Injection site mass 20%
  • Widening of blood vessels 15%
  • Injection site edema 15%
  • Nausea 14%
  • Shortness of breath 10%
  • Injection site inflammation 8%
More Copaxone side effects »
  • Flu-like symptoms 20%
  • Chills 14%
  • Fever 11%
  • Muscle pain 7%
  • Muscle weakness 6%
  • Nausea 4%
  • Injuction site inflammation 4%
  • Low mood disorder 4%
  • Infection 3%
  • Chest pain 3%
More Avonex side effects »
  • Low white blood cells 12%
More Betaseron side effects »
  • Alt/ast increased 9%
  • Diarrhea 5%
  • Back pain 5%
  • Ggt increased 4%
  • Bronchitis 4%
  • Migraine 4%
  • Vission blurred 3%
  • Abnormally slow heartbeat 3%
  • Influenza viral infections 3%
  • Tinea infections 3%
More Gilenya side effects »
  • Flu-like symptoms 20%
  • Chills 14%
  • Fever 11%
  • Muscle pain 7%
  • Muscle weakness 6%
  • Nausea 4%
  • Injuction site inflammation 4%
  • Low mood disorder 4%
  • Infection 3%
  • Chest pain 3%
More Avonex side effects »
  • Hair loss or baldness 10%
  • Diarrhea 9%
  • Mild hypophospatemia 9%
  • Alanine aminotransferase increased 7%
  • Nausea 7%
  • Headache 4%
  • Moderate hypophospatemia 4%
  • Gamma-glutamyltransferase increase 4%
  • Gastroenteritis viral 3%
  • Bladder infection 3%
More Aubagio side effects »
How it works
CopaxoneAvonexBetaseronGilenyaAvonexAubagio
Copaxone (Glatiramer) is an immune modulator that alters the immune process. Researchers don't know exactly how it works. It's thought to "trick" out-of-control immune cells and slow their attacks on nerves.Avonex (Interferon Beta-1A) is an interferon that acts like the ones your body naturally makes. Researchers don't know exactly how it works, but interferons activate your immune system to control immune responses that have gotten out of control.Betaseron (Interferon Beta-1B) is a man-made interferon that's similar to what your body naturally makes. Researchers don't know exactly how it works for MS, but interferons activate your own immune system to control immune responses that have gone out of control.Gilenya (Fingolimod) is an immune modulator. Researchers don't know exactly how it works, but it seems to stop your white blood cells from attacking the nerves in your brain and spinal cord.Avonex (Interferon Beta-1A) is an interferon that acts like the ones your body naturally makes. Researchers don't know exactly how it works, but interferons activate your immune system to control immune responses that have gotten out of control.Aubagio (Teriflunomide) is an immune modulator. Researchers don't know exactly how it works for MS, but it seems to lower your white blood cells and keep them from attacking the nerves in your brain and spinal cord.
Type of medication
CopaxoneAvonexBetaseronGilenyaAvonexAubagio
Multiple sclerosis treatment
Immunomodulator
Prescription only
Multiple sclerosis treatment
Immunomodulator
Prescription only
Multiple Sclerosis treatment
Immunomodulator
Prescription only
Multiple sclerosis treatment, Immunosuppressant
Immunomodulator
Prescription only
Multiple sclerosis treatment
Immunomodulator
Prescription only
Multiple Sclerosis treatment
Pyrimidine synthesis inhibitor
Prescription only
Available as
CopaxoneAvonexBetaseronGilenyaAvonexAubagio
  • Injection
  • Injection
  • Injection
  • Pill
  • Injection
  • Pill
Used for (click to learn more)
CopaxoneAvonexBetaseronGilenyaAvonexAubagio
Risk factors for serious side effects
CopaxoneAvonexBetaseronGilenyaAvonexAubagio
            Detailed Copaxone (Glatiramer) risks & warnings »
            Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.
            Pregnancy category
            CopaxoneAvonexBetaseronGilenyaAvonexAubagio
            BFDA pregnancy category (Probably safe)

            Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

            See the FDA package insert
            CFDA pregnancy category (Weigh risks vs. benefits)

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            See the FDA package insert
            CFDA pregnancy category (Weigh risks vs. benefits)

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            See the FDA package insert
            CFDA pregnancy category (Weigh risks vs. benefits)

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            See the FDA package insert
            CFDA pregnancy category (Weigh risks vs. benefits)

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            See the FDA package insert
            XFDA pregnancy category (Unsafe)

            Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

            See the FDA package insert
            Alcohol
            No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.
            Food
            No specific food-related info.No specific food-related info.No specific food-related info.
            • Take one capsule daily with or without food.
            No specific food-related info.
            • It comes a 7 mg and 14mg dose and only needs to be taken once a day, with or without food.
            • Take one capsule daily with or without food.
            Kidneys and liver
            No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.
            • Aubagio can also cause serious and life-threatening liver, lung, skin, kidney and blood pressure effects.
            Sex
            No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.
            Sleep
            No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.
            Weight
            No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.No specific weight-related info.
            Upsides and benefits
            CopaxoneAvonexBetaseronGilenyaAvonexAubagio
            • One of the main treatments for relapsing multiple sclerosis (MS) that has been around for many years.
            • Fewer side effects than other injectable MS medicines, like interferons.
            • Can be helpful in maintaining nerve functions.
            • Likely safe to use during pregnancy.
            • Copaxone (Glatiramer) is a possible treatment for primary-progressive MS (PPMS) even though the clinical evidence is not conclusive (there are currently no approved treatments for PPMS).
            • Helps reduce the frequency of MS relapse episodes.
            • One of the main treatments for relapsing MS that has been around for many years.
            • Injections are given weekly, and not daily like other MS medications.
            • Helps reduce the frequency of MS relapse episodes.
            • Flu-like reactions are the most common side effects and usually go away with continued treatment or can be avoided by using over-the-counter pain and fever-reducing medicines before the injection (like acetaminophen or ibuprofen).
            • Interferon beta-1b was the first disease modifying agent for MS approved by the FDA to treat relapsing-remitting multiple sclerosis (RRMS).
            • In short and long-term follow-up studies, Interferon beta-1b was shown to slow MS progression, reduce the number of flair-ups and increase overall survival.
            • Convenient every-other-day dosing and refrigeration-free storage (before mixing) is less of a hassle.
            • Interferon beta-1b has been shown to be more effective than Avonex in reducing new lesions, which lowers relapse and disease progression in people with RRMS.
            • May be a treatment option for people with secondary progressive multiple sclerosis (SPMS).
            • Gilenya (Fingolimod) is the first once-daily pill you can take for relapsing forms of multiple sclerosis (MS).
            • Studies show it lowers relapse rates better than placebo and Avonex, and it delays the progression of physical disabilites better than placebo.
            • Gilenya also reduced the number of new MS lesions better than Avonex.
            • One of the main treatments for relapsing MS that has been around for many years.
            • Injections are given weekly, and not daily like other MS medications.
            • Helps reduce the frequency of MS relapse episodes.
            • Flu-like reactions are the most common side effects and usually go away with continued treatment or can be avoided by using over-the-counter pain and fever-reducing medicines before the injection (like acetaminophen or ibuprofen).
            • You can take it by mouth.
            • It comes a 7 mg and 14mg dose and only needs to be taken once a day, with or without food.
            • In clinical studies, Aubagio reduced relapses, slowed disability, and decreased the number of new brain lesions compared to sugar pill (placebo).
            • Although it may not work for everyone, most people felt it wasn't much of a hassle.
            Downsides and risks
            CopaxoneAvonexBetaseronGilenyaAvonexAubagio
            • Requires injections, either day or every other day (but no more than three times a week), depending on the dose you're taking.
            • Injection site reactions are common with pain, redness, swelling, and lipoatrophy (loss of fat under the skin where the injection is made).
            • Doesn't stop the progression of MS.
            • Injection site reactions are common, ranging from localized pain, redness, and swelling to severe skin dryness.
            • Flu-like symptoms are common after interferon injections.
            • It's not clear what type of problems occur if taken during pregnancy.
            • Blood testing is required before and during use of Avonex (Interferon Beta-1A).
            • May not be as effective as other interferons.
            • Requires injections.
            • Injection site reactions are common. Symptoms range from pain, redness, and swelling to severe reactions with skin death around the injection site.
            • Flu-like symptoms are common after interferon injections, but are less likely with Interferon beta-1b in particular.
            • Blood testing required before and during use based on your other conditions.
            • Unclear consequences to fetus during pregnancy.
            • Taking more than the 0.5 mg dose won't give more benefits, but will only cause more side effects.
            • Gilenya can remain in your blood for up to 2 months after you stop taking it. Your immune response won't work as well during this time.
            • Not the best choice if you've had a heart attack, stroke, or have been in the hospital for heart failure in the past 6 months. The risk of serious heart rate effects is higher when taken with certain drugs (methadone, erythromycin, citalopram, ketoconazole) or if you have low potassium or magnesium.
            • If you have to re-start Gilenya after stopping it for 2 weeks or more, you'll have to take your first dose at your doctor's office again.
            • If you didn't get chicken pox and never had a vaccination, you'll need to be vaccinated and wait one month before starting Gilenya.
            • Injection site reactions are common, ranging from localized pain, redness, and swelling to severe skin dryness.
            • Flu-like symptoms are common after interferon injections.
            • It's not clear what type of problems occur if taken during pregnancy.
            • Blood testing is required before and during use of Avonex (Interferon Beta-1A).
            • May not be as effective as other interferons.
            • Some people have nausea and diarrhea when they start treatment. In most cases, these effects are mild and get better over time.
            • Aubagio can cause your hair to thin. This is temporary, and your hair will go back to normal after a few months.
            • You should have certain lab tests to make sure you don't have any problems from taking Aubagio. These include: complete blood count and liver enzyme testing within 6 months before you start treatment, tuberculosis (TB) screening, and blood pressure.
            • Numbness or tingling in your hands and feet (peripheral neuropathy), different from MS was reported more often than with sugar pill (placebo)
            • Aubagio may stay in your blood up to 2 years after you stop taking it. You can quickly remove Aubagio the accelerated elimination procedure, but symptoms of your disease may return.
            • You can't take it if you're pregnant.
            Tips from our pharmacists for people taking the medication
            CopaxoneAvonexBetaseronGilenyaAvonexAubagio
            • Inject yourself at the same time every day into your subcutaneous fat (the layer between your skin and muscle).
            • Injection site reactions are common. Symptoms include swelling, redness, and pain.
            • Rarely, can cause a fast and irregular heartbeat, shortness of breath, or flushing that usually goes away after 10-15 minutes.
            • You can keep syringes at room temperature for up to a month if you can't store them in the refrigerator.
            • Inject yourself once a week in your muscle (you need to go deeper than the fat layer between your skin and muscle).
            • Refrigerate the powder and pre-filled syringes and pens.
            • Don't shake the medicine once it is taken out of the refrigerator or mixed.
            • If using the pre-filled syringes, the tiny air bubbles won't hurt you.
            • Avonex (Interferon Beta-1A) can cause flu-like symptoms (headache, fever, muscle pain) right after injections, lasting minutes or hours.
            • Flu-like reactions usually go away with repeated treatments. Taking acetaminophen or ibuprofen 45 minutes before the injection can reduce the uncomfortable feeling.
            • Every-other-day injections to the fatty layer under your skin.
            • Store the powder for reconstitution at room temperature.
            • Don't shake the medicine after reconstitution.
            • Can cause flu-like symptoms (headache, fever, muscle pain) right after injections lasting minutes or hours.
            • Flu-like reactions usually goes away with repeated treatments, or taking acetaminophen or ibuprofen 45 minutes before the injection to reduce the uncomfortable feeling.
            • Injection site reactions can be common, including swelling, redness, pain, and rarely death of surrounding skin tissues.
            • It's very important you read the Gilenya Medication Guide. Don't change your dose or stop the medicine without asking your doctor.
            • You'll need to be watched for at least 6 hours in a doctor's office after taking your first dose because it can cause serious heart rate and blood pressure problems.
            • Gilenya increases your risk of infections. Get blood tests 6 months before starting treatment.
            • Use effective birth control or plan to stop Gilenya 2 months before getting pregnant. If you do become pregnant while on Gilenya (Fingolimod), you'll need to enroll in the Gilenya pregnancy registry.
            • Tell your doctor if you've had any vaccines recently. Don't get any live vaccines while taking Gilenya.
            • Your doctor will monitor your eyes, lungs, and liver for up to 2 months after stopping Gilenya.
            • Take one capsule daily with or without food.
            • Inject yourself once a week in your muscle (you need to go deeper than the fat layer between your skin and muscle).
            • Refrigerate the powder and pre-filled syringes and pens.
            • Don't shake the medicine once it is taken out of the refrigerator or mixed.
            • If using the pre-filled syringes, the tiny air bubbles won't hurt you.
            • Avonex (Interferon Beta-1A) can cause flu-like symptoms (headache, fever, muscle pain) right after injections, lasting minutes or hours.
            • Flu-like reactions usually go away with repeated treatments. Taking acetaminophen or ibuprofen 45 minutes before the injection can reduce the uncomfortable feeling.
            • It's very important you read the Aubagio Medication Guide.
            • Most common side effects are diarrhea, nausea, hair thinning, and elevated liver blood levels.
            • Not the best choice if you have liver problems or are on medications that affect the liver.
            • Liver blood tests need to be done for 6 months once you start taking Aubagio. If these tests are abnormal and liver damage is suspected your doctor will stop the medicine and tell you to start taking cholestyramine for 11 days to lower the toxic level.
            • You'll need to have a TB test before you start taking Aubagio.
            • Can cause numbness and tingling of your hands and feet. Let your doctor know if this becomes a problem.
            • Aubagio increases your risk of infections so tell your doctor if you notice a fever, cough that doesn't go away, or flu-like symptoms. Get your blood counts checked 6 months before starting treatment.
            • Aubagio can also cause serious and life-threatening liver, lung, skin, kidney and blood pressure effects.
            • Aubagio will harm your unborn baby and is pregnancy category X. You must have a negative pregnancy test before starting Aubagio.
            • Both men and women are affected. If they want to have a baby both need to stop taking Aubagio and begin rapid removal process using cholestyramine or activated charcoal for 11 days. Without this process, Aubagio will stay in the body for up to 2 years.
            • Take one capsule daily with or without food.
            Learn more
            More about CopaxoneSide effectsReviews & ratingsAlternativesFDA package insert
            More about AvonexSide effectsReviews & ratingsFDA package insert
            More about BetaseronSide effectsReviews & ratingsFDA package insert
            More about GilenyaSide effectsReviews & ratingsFDA package insert
            More about AvonexSide effectsReviews & ratingsFDA package insert
            More about AubagioSide effectsReviews & ratingsFDA package insert