Prescription onlyLower-cost generic availableClass: Cardiovascular

CrestorAlternatives

(rosuvastatin)

Prescription onlyLower-cost generic availableClass: Cardiovascular
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Compare Crestor (rosuvastatin) to alternatives

These medications are comparable to Crestor (rosuvastatin) or used for similar purposes.

Crestor
(rosuvastatin)

Lipitor
(atorvastatin)

Mevacor
(lovastatin)

Zocor
(simvastatin)

Pravachol
(pravastatin)

Vytorin
(ezetimibe / simvastatin)

Livalo
(pitavastatin)

Lowers cholesterol. Crestor (rosuvastatin) is one of the most effective statins to improve cholesterol. It's also available as a generic.Lowers cholesterol. Lipitor (atorvastatin) improves your cholesterol levels and is a common first treatment for people with high cholesterol or heart disease.Lowers cholesterol. Mevacor (Lovastatin) can improve cholesterol, but it's not as strong as other statin medicines. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.Lowers cholesterol. Zocor (Simvastatin) is a good medication to improve your cholesterol. Statin side effects can be difficult to deal with, but the benefits might outweigh the risks.Lowers cholesterol. Pravachol (pravastatin) can improve cholesterol, but it's not as strong as other statin medicines. It does cause fewer side effects and is safer for your kidneys and liver.Lowers cholesterol. Vytorin is expensive and is no more effective than simvastatin by itself.Coming soon.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.02Crestor
Reviews for Crestor (rosuvastatin)
60%
of people (All ages) say Crestor (rosuvastatin) is worth it
47%
say it works well
15%
say it's a big hassle
751 reviews
Have you used Crestor (rosuvastatin)?
Worth itNot sureNot worth it
Reviews for Lipitor (atorvastatin)
63%
+3% better vs. Crestor (rosuvastatin)
51%
+4% better vs. Crestor (rosuvastatin)
13%
+2% better vs. Crestor (rosuvastatin)
1377 reviews
Have you used Lipitor (atorvastatin)?
Worth itNot sureNot worth it
Reviews for Mevacor (lovastatin)
43%
-17% worse vs. Crestor (rosuvastatin)
39%
-8% worse vs. Crestor (rosuvastatin)
22%
-7% worse vs. Crestor (rosuvastatin)
Have you used Mevacor (lovastatin)?
Worth itNot sureNot worth it
Reviews for Zocor (simvastatin)
61%
+1% better vs. Crestor (rosuvastatin)
48%
+1% better vs. Crestor (rosuvastatin)
14%
+1% better vs. Crestor (rosuvastatin)
1176 reviews
Have you used Zocor (simvastatin)?
Worth itNot sureNot worth it
Reviews for Pravachol (pravastatin)
54%
-6% worse vs. Crestor (rosuvastatin)
44%
-3% worse vs. Crestor (rosuvastatin)
19%
-4% worse vs. Crestor (rosuvastatin)
426 reviews
Have you used Pravachol (pravastatin)?
Worth itNot sureNot worth it
Reviews for Vytorin (ezetimibe / simvastatin)
53%
-7% worse vs. Crestor (rosuvastatin)
36%
-11% worse vs. Crestor (rosuvastatin)
19%
-4% worse vs. Crestor (rosuvastatin)
Have you used Vytorin (ezetimibe / simvastatin)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Livalo (pitavastatin)?
Worth itNot sureNot worth it
Side effects
CrestorAtorvastatinLovastatinSimvastatinpravastatinVytorinLivalo
  • Headache 1%
  • Nausea 1%
  • Muscle pain 2%
  • Joint pain 1%
  • Diabetes mellitus 1%
  • Dizziness 1%
More Crestor side effects »
  • Diarrhea 1%
  • Indigestion 1%
  • Muscle spasms 1%
  • Muscle pain 1%
More Atorvastatin side effects »
  • Diarrhea 1%
  • Muscle pain 1%
  • Muscle weakness 1%
  • Elevations of ck levels 11%
More Lovastatin side effects »
  • Upper respiratory infections 9%
  • Abdominal pain 7%
  • Constipation 7%
  • Headache 7%
  • Bronchitis 1%
  • Abnormal heart rhythm 1%
  • Nausea 5%
  • Scaly, itchy rash 2%
  • Upset stomach 3%
  • Vertigo 1%
More Simvastatin side effects »
  • Upper respiratory infection 4%
  • Diarrhea 3%
  • Headache 2%
  • Chest pain 2%
  • Sore throat 2%
  • Rash 2%
  • Muscle pain 2%
More pravastatin side effects »
  • Headache 1%
  • Any side effect 3%
  • Muscle pain 4%
  • Ear, nose, or throat infection 4%
  • Increased alt 4%
  • Diarrhea 3%
  • Flu 1%
  • Pain in extremity 1%
  • Unexplained muscle pain or weakness 1%
More Vytorin side effects »

We haven’t found good data for Livalo side effects.

FDA side effect reports for Livalo »
How it works
CrestorAtorvastatinLovastatinSimvastatinpravastatinVytorinLivalo
Crestor (rosuvastatin) is a statin medication that changes the amount of cholesterol your body makes. It lowers "bad" cholesterol (LDL) and improves your "good" cholesterol (HDL) levels.Lipitor (atorvastatin) is a cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Mevacor (Lovastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Zocor (Simvastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Pravachol (pravastatin) is cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).Vytorin is a combination cholesterol-lowering medicine. Simvastatin prevents your body from making "bad" cholesterol (LDL) while raising "good" cholesterol (HDL). Ezetimibe prevents cholesterol absorption in your intestines.Coming soon.
Type of medication
CrestorAtorvastatinLovastatinSimvastatinpravastatinVytorinLivalo
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Available as
CrestorAtorvastatinLovastatinSimvastatinpravastatinVytorinLivalo
  • Pill
  • Pill
  • Pill
  • Extended release
  • Pill
  • Dissolving tablet
  • Pill
  • Pill
  • Pill
Used for
CrestorAtorvastatinLovastatinSimvastatinpravastatinVytorinLivalo
  • Hyperlipidemia
Risk factors for serious side effects
CrestorAtorvastatinLovastatinSimvastatinpravastatinVytorinLivalo
  • Taking Coumadin (warfarin)
  • Age 65 or older
  • Taking higher doses of Crestor (rosuvastatin)
  • Diabetes
  • Heavy alcohol use
  • Prior history of chronic liver disease
  • Pregnancy
Detailed Crestor (rosuvastatin) risks & warnings »
    • Heavy alcohol use
    • Prior history of chronic liver disease
    • Pregnancy
    • History of hemorrhagic strokes
      Detailed Lipitor (atorvastatin) risks & warnings »
      • Kidney disease
      • High dose of Mevacor (Lovastatin)
      • Combining with certain cholesterol-lowering drugs
      • Older age and female gender
      • Heavy alcohol use
      • History of chronic liver disease
      • Pregnancy
      • Breast feeding
      • Taking with certain drugs that increase the dose of Mevacor (Lovastatin) in the body
        Detailed Mevacor (lovastatin) risks & warnings »
        • Kidney disease
        • High dose of Zocor (Simvastatin)
        • Combining Zocor (Simvastatin) with certain cholesterol-lowering drugs
        • Older age and female gender
        • Heavy alcohol use
        • History of chronic liver disease
        • Pregnancy
        • Breast feeding
        • Certain drugs can increase the dose of Zocor (Simvastatin) in the body
          Detailed Zocor (simvastatin) risks & warnings »
          • Kidney disease
          • An underactive thyroid
          • Over age 65
          • Female gender
          • Taking other medicines to lower your cholesterol
          • Heavy alcohol use
          • History of chronic liver disease
          • Pregnancy
          • Breast feeding
          • Spironolactone use
          • Cimetidine use
          • Ketoconazole use
          Detailed Pravachol (pravastatin) risks & warnings »
          • Asian patients taking high-dose niacin
          • Past history of liver disease
          • heavy alcohol use
          • Diabetes
              • Pregnancy
              Detailed Vytorin (ezetimibe / simvastatin) risks & warnings »
              Coming soon.
              Pregnancy

              Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

              Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

              Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

              Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

              Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

              Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

              Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

              Interactions
              CrestorAtorvastatinLovastatinSimvastatinpravastatinVytorinLivalo
              No interactions related info.No interactions related info.
              • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
              • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
              No interactions related info.No interactions related info.No interactions related info.
              Alcohol
              CrestorAtorvastatinLovastatinSimvastatinpravastatinVytorinLivalo
              • You're more likely to have side effects if you're a female, are 65 years or older, drink alcohol every day, or take more than one medicine for cholesterol.
              • Don't have more than 2 glasses of alcohol a day since Crestor (rosuvastatin) can cause liver damage.
              • You're at higher risk for these side effects if you are a female, are 65 years or older, or drink more than two alcoholic drinks a day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
              • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
              • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
              No alcohol related info.No alcohol related info.No alcohol related info.
              Food
              CrestorAtorvastatinLovastatinSimvastatinpravastatinVytorinLivalo
              No food related info.No food related info.
              • Works best if you take it once a day after your evening meal.
              No food related info.No food related info.No food related info.No food related info.
              Kidneys and liver
              CrestorAtorvastatinLovastatinSimvastatinpravastatinVytorinLivalo
              • People with liver disease, kidney disease, or diabetes are also more likely to have side effects from Crestor (rosuvastatin).
              • People on Crestor (rosuvastatin) have reported muscle pain which can lead to muscle or kidney damage. This is more likely to happen if you're older and if you're taking higher doses of Crestor (rosuvastatin). If you suddenly feel severe muscle pain or weakness and you haven't been exercising, stop taking Crestor (rosuvastatin) and talk to your doctor right away.
              • Crestor (rosuvastatin) can cause liver damage. If your urine is darker than normal or if you notice a yellow color in your eyes or skin, talk to your doctor. Your doctor may run some tests to see how your liver is working.
              • Statins such as Lipitor (atorvastatin) can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, or liver damage. Some people need to stop taking this medicine if these problems occur.
              • Eating grapefruit or drinking grapefruit juice can raise your risk of liver damage while taking Lipitor (atorvastatin).
              • People on Lipitor (atorvastatin) have reported muscle pain, which may lead to muscle and kidney damage. This is more likely to happen if you're older and you're taking higher doses of Lipitor (atorvastatin). If you suddenly feel muscle pain or weakness and you haven't been exercising, stop taking Lipitor (atorvastatin) and talk to your doctor right away.
              • Liver damage has been reported in people who take Lipitor (atorvastatin). If you notice dark urine or yellowing of your eyes or skin, talk to your doctor. Your doctor might run blood tests to check your liver.
              • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
              • There are rare cases of muscle damage leading to kidney failure in people taking Mevacor (Lovastatin). The risk is greater in people with kidney disease or thyroid disease, are older and female and taking certain cholesterol-lowering medication combinations. Tell your doctor if you develop sudden muscle pain, weakness or fever and there is no known cause.
              • There are reports of liver damage in people who take Mevacor (Lovastatin), especially if they are heavy alcohol drinkers or have a history of liver disease. If you notice dark urine or yellowing of the eyes or skin, tell your doctor. Your doctor may also want to check your liver function periodically.
              • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
              • There are rare cases of muscle damage leading to kidney failure in people taking Zocor (Simvastatin). The risk is greater in people with kidney disease or thyroid disease, are older and female and taking certain cholesterol-lowering medication combinations. Tell your doctor if you develop sudden muscle pain, weakness or fever and there is no known cause.
              • There are reports of liver damage in people who take Zocor (Simvastatin), especially if they are heavy alcohol drinkers or have a history of liver disease. If you notice dark urine or yellowing of the eyes or skin, tell your doctor. Your doctor may also want to check your liver function periodically.
              • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
              • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
              • People on Vytorin (Ezetimibe / Simvastatin) have reported muscle pain which may lead to muscle breakdown and kidney damage, especially in people of Asian ancestry who are also taking niacin. This has been very rare. Talk to your doctor if you suddenly develop muscle pain and a fever and you don't know why.
              No kidneys and liver related info.
              Pain
              CrestorAtorvastatinLovastatinSimvastatinpravastatinVytorinLivalo
              • Crestor (rosuvastatin) isn't safe to use if you're pregnant since it can hurt the fetus.
              • Call your doctor if you have sudden muscle pain, fever, or weakness.
              • Tell your doctor if you suddenly feel severe muscle pain, fever, or weakness.
              • Combining certain medications can increase the risk of muscle pain (myopathy), muscle damage (rhabdomyolysis) and kidney damage. Talk to your doctor or pharmacist when taking any new medications.
              • Combining certain medications can increase the risk of muscle pain (myopathy), muscle damage (rhabdomyolysis) and kidney damage. Talk to your doctor or pharmacist when taking any new medications.
              No pain related info.No pain related info.No pain related info.
              Upsides and benefits
              CrestorAtorvastatinLovastatinSimvastatinpravastatinVytorinLivalo
              • It's a good first choice medicine for lowering cholesterol levels when diet and exercise aren't enough.
              • Slows down the buildup of fatty deposits in your blood vessels, otherwise known as a hardening of the arteries.
              • In clinical studies, Crestor (rosuvastatin) has the strongest effect on lowering "bad" cholesterol compared to other statins.
              • Can lower your risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
              • Available as a generic drug.
              • Lowers "bad" cholesterol (LDL) and triglycerides (fats), and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
              • Lipitor (atorvastatin) can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
              • It's one of the strongest cholesterol-lowering statin medications.
              • Lipitor (atorvastatin) is a good option for people who have high cholesterol and diabetes.
              • It's available as a generic drug and can be used in combination with other cholesterol lowering drugs.
              • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
              • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
              • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
              • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
              • Compared to other statins, Pravachol (pravastatin) has fewer interactions with medicines.
              • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
              • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
              • It's available as a generic.
              • A 2-in-1 cholesterol-lowering combination medicine.
              • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
              Coming soon
              Downsides and risks
              CrestorAtorvastatinLovastatinSimvastatinpravastatinVytorinLivalo
              • You're more likely to have side effects if you're a female, are 65 years or older, drink alcohol every day, or take more than one medicine for cholesterol.
              • People with liver disease, kidney disease, or diabetes are also more likely to have side effects from Crestor (rosuvastatin).
              • Crestor (rosuvastatin) isn't safe to use if you're pregnant since it can hurt the fetus.
              • Statins such as Lipitor (atorvastatin) can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, or liver damage. Some people need to stop taking this medicine if these problems occur.
              • You're at higher risk for these side effects if you are a female, are 65 years or older, or drink more than two alcoholic drinks a day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
              • Eating grapefruit or drinking grapefruit juice can raise your risk of liver damage while taking Lipitor (atorvastatin).
              • Not the best choice for people who have very high cholesterol levels.
              • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
              • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
              • Not safe to use if you're pregnant.
              • Statins can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, and liver damage. Some people have to stop taking this medicine because of these problems.
              • You're at higher risk for these side effects if you are female, are 65 years or older, drink alcohol every day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
              • Not safe to use if you're pregnant.
              • Pravachol (pravastatin) isn't as strong as other statins in lowering your cholesterol.
              • You'll still need to eat a low fat diet and exercise regularly to get the full benefit of Pravachol (pravastatin).
              • In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
              • There's no generic available, so it can be expensive.
              Coming soon
              Tips from our pharmacists for people taking the medication
              CrestorAtorvastatinLovastatinSimvastatinpravastatinVytorinLivalo
              • Lowers bad cholesterol and triglycerides, and raises good cholesterol levels.
              • Don't have more than 2 glasses of alcohol a day since Crestor (rosuvastatin) can cause liver damage.
              • Don't take antacids for at least 2 hours before and after taking Crestor (rosuvastatin).
              • Call your doctor if you have sudden muscle pain, fever, or weakness.
              • Let your doctor know if you have dark urine or a yellow color in your eyes or skin.
              • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
              • Don't eat grapefruit or drink grapefruit juice while taking this medicine.
              • Tell your doctor if you suddenly feel severe muscle pain, fever, or weakness.
              • Also tell your doctor if you have dark urine or if you notice a yellow tint in your eyes or skin.
              • Lipitor (atorvastatin) isn't safe to use if you're pregnant.
              • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
              • Most people reach their target cholesterol levels in 4 to 6 weeks.
              • Works best if you take it once a day after your evening meal.
              • Avoid grapefruit and grapefruit juice while taking this medicine.
              • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
              • Tell your doctor if you notice dark urine or yellowing of the eyes or skin.
              • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
              • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
              • Most people reach their target cholesterol levels in 4 to 6 weeks.
              • Avoid grapefruit and grapefruit juice while taking this medicine.
              • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
              • Tell your doctor if you notice dark urine or yellowing of the eyes or skin.
              • Certain medications can interact with this drug. Talk to your doctor or pharmacist.
              • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
              • Most people reach their target cholesterol levels in 4 to 6 weeks.
              • Don't eat grapefruit and drink grapefruit juice while taking this medicine.
              • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
              • Also let your doctor know if you notice dark urine or yellowing of your eyes or skin.
              • You'll need to stop taking Pravachol (pravastatin) if you get pregnant.
              • Take it in the evening.
              • Avoid grapefruit and grapefruit juice while taking this medicine.
              • Can cause headaches or diarrhea.
              • Call your doctor if you develop muscle pain.
              • Also taking Welchol or Questran? Take this medicine at least 2 hours before or 4 hours after.
              Coming soon
              Learn more
              More about CrestorSide effectsReviews & ratingsAlternativesFDA package insert
              Have you used Crestor (rosuvastatin)?
              Worth itNot sureNot worth it
              More about AtorvastatinSide effectsReviews & ratingsFDA package insert
              Have you used Lipitor (atorvastatin)?
              Worth itNot sureNot worth it
              More about LovastatinSide effectsReviews & ratingsFDA package insert
              Have you used Mevacor (lovastatin)?
              Worth itNot sureNot worth it
              More about SimvastatinSide effectsReviews & ratingsFDA package insert
              Have you used Zocor (simvastatin)?
              Worth itNot sureNot worth it
              More about pravastatinSide effectsReviews & ratingsFDA package insert
              Have you used Pravachol (pravastatin)?
              Worth itNot sureNot worth it
              More about VytorinSide effectsReviews & ratingsFDA package insert
              Have you used Vytorin (ezetimibe / simvastatin)?
              Worth itNot sureNot worth it
              More about LivaloSide effectsReviews & ratingsFDA package insert
              Have you used Livalo (pitavastatin)?
              Worth itNot sureNot worth it