Prescription onlyClass: Mental health

DaytranaAlternatives

(methylphenidate)

Prescription onlyClass: Mental health
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Compare Daytrana (methylphenidate) to alternatives

These medications are comparable to Daytrana (methylphenidate) or used for similar purposes.

Daytrana
(methylphenidate)

Vyvanse
(lisdexamfetamine)

Focalin
(dexmethylphenidate)

Kapvay
(clonidine)

Provigil
(modafinil)

Desoxyn
(methamphetamine)

Strattera
(atomoxetine)

Adderall
(dextroamphetamine / amphetamine)

Helps you stay awake and focus. Daytrana (Methylphenidate) is an effective medication used to treat ADHD and can be used as a patch.Helps you focus and stay alert. Vyvanse (Lisdexamfetamine) is a first-choice treatment for ADHD and you only have to take it once a day. However, it's only available as brand name drug, so it can be expensive.Helps you focus and stay alert. Focalin (Dexmethylphenidate) is a first-choice treatment for ADHD that's available as a generic, but it's a stimulant, so it can cause insomnia and other side effects.Treats ADHD and lowers blood pressure. Clonidine is a non-stimulant option to manage ADHD symptoms and behaviors, but it can lower your blood pressure.Improves alertness. Provigil (Modafinil) is effective in improving alertness, but it can interact with other medicines and shouldn't be used long-term.Helps you focus and lose weight. Desoxyn (Methamphetamine) is an effective and cheap medication used to treat ADHD, but it can be habit-forming and is not used for long-term treatment.Helps you focus and stay alert. Strattera (Atomoxetine) isn't considered a first-line medication for ADHD, but since it isn't a stimulant, it's still highly recommended.Helps you focus and stay alert. Adderall (Dextroamphetamine / Amphetamine) is a first-choice treatment for ADHD that's available as a generic, but it's a stimulant, so it can cause insomnia and other side effects.
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Reviews & ratings
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Not enough reviews for this drug. Help someone out, leave a review!

Have you used Daytrana (methylphenidate)?
Worth itNot sureNot worth it
Reviews for Vyvanse (lisdexamfetamine)
67%
-33% worse vs. Daytrana (methylphenidate)
49%
-37% worse vs. Daytrana (methylphenidate)
17%
+12% better vs. Daytrana (methylphenidate)
491 reviews
Have you used Vyvanse (lisdexamfetamine)?
Worth itNot sureNot worth it
Reviews for Focalin (dexmethylphenidate)
55%
-45% worse vs. Daytrana (methylphenidate)
35%
-51% worse vs. Daytrana (methylphenidate)
21%
+8% better vs. Daytrana (methylphenidate)
141 reviews
Have you used Focalin (dexmethylphenidate)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Kapvay (clonidine)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Provigil (modafinil)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Desoxyn (methamphetamine)?
Worth itNot sureNot worth it
Reviews for Strattera (atomoxetine)
46%
-54% worse vs. Daytrana (methylphenidate)
32%
-54% worse vs. Daytrana (methylphenidate)
24%
+5% better vs. Daytrana (methylphenidate)
Have you used Strattera (atomoxetine)?
Worth itNot sureNot worth it
Reviews for Adderall (dextroamphetamine / amphetamine)
74%
-26% worse vs. Daytrana (methylphenidate)
53%
-33% worse vs. Daytrana (methylphenidate)
16%
+13% better vs. Daytrana (methylphenidate)
1309 reviews
Have you used Adderall (dextroamphetamine / amphetamine)?
Worth itNot sureNot worth it
Side effects
DaytranaVyvanseFocalinKapvayProvigilDesoxynStratteraAdderall
  • Decreased appetite 25%
  • Headache 3%
  • Sleep difficulty 8%
  • Nausea 10%
  • Irritability 4%
  • Vomiting 5%
  • Weight decreased 9%
  • Abdominal pain 1%
More Daytrana side effects »
  • Decreased appetite 35%
  • Sleep difficulty 20%
  • Abdominal pain upper 6%
  • Irritability 10%
  • Any side effect 8%
  • Vomiting 5%
  • Weight loss 8%
  • Nausea 3%
  • Dry mouth 5%
  • Dizziness 5%
More Vyvanse side effects »

We haven’t found good data for Focalin side effects.

FDA side effect reports for Focalin »
  • Drowsiness 34%
  • Headache 4%
  • Fatigue 15%
  • Upper abdominal pain 3%
  • Irritability 5%
  • Any side effect 6%
  • Dizziness 2%
  • Sleep difficulty 4%
  • Nausea 1%
  • Emotional disorder 3%
More Kapvay side effects »
  • Headache 11%
  • Nausea 8%
  • Any side effect 5%
  • Inflammation inside the nose 1%
  • Nervousness 4%
  • Back pain 1%
  • Diarrhea 1%
  • Dizziness 1%
  • Sleep difficulty 4%
  • Indigestion 1%
More Provigil side effects »

We haven’t found good data for Desoxyn side effects.

FDA side effect reports for Desoxyn »
  • Headache 4%
  • Abdominal pain 8%
  • Decreased appetite 12%
  • Vomiting 5%
  • Drowsiness 7%
  • Changes in heart rate or blood pressure 10%
  • Nausea 5%
  • Fatigue 5%
  • Irritability 3%
  • Dizziness 3%
More Strattera side effects »

The Adderall FDA package insert doesn’t have numbers about how common side effects are.

More about Adderall side effects »
How it works
DaytranaVyvanseFocalinKapvayProvigilDesoxynStratteraAdderall
Daytrana (Methylphenidate) is a stimulant. It treats narcolepsy and attention-deficit/hyperactivity disorder (ADHD) by increasing norepinephrine and dopamine activity in the brain.Vyvanse (Lisdexamfetamine) is an amphetamine stimulant. Researchers don't know exactly how it works for ADHD, but it increases norepinephrine and dopamine activity in the brain, which affects attention and behavior.Focalin (Dexmethylphenidate) is a stimulant. Researchers don't know exactly how it works for ADHD, but it increases norepinephrine and dopamine activity in the brain, which affects attention and behavior.Clonidine is an alpha-2 agonist. Researchers don't know exactly how it works for ADHD. It works in the brain and lowers the activity of certain stress hormones, but it's not a stimulant like many ADHD medicines.Provigil (Modafinil) is a stimulant that helps you feel awake. Researchers don't know exactly how Provigil (Modafinil) works, but it probably affects chemicals (neurotransmitters) in the brain.Desoxyn (Methamphetamine) is a stimulant. It treats attention-deficit/hyperactivity disorder (ADHD) and weight loss by increasing norepinephrine and dopamine activity in the brain.Strattera (Atomoxetine) is a norepinephrine reuptake inhibitor (non-stimulant). Researchers don't know exactly how it works for ADHD, but it increases norepinephrine activity in the brain, which affects attention and behavior.Adderall (Dextroamphetamine / Amphetamine) is an amphetamine stimulant. Researchers don't know exactly how it works for ADHD, but it increases norepinephrine and dopamine activity in the brain, which affects attention and behavior.
Type of medication
DaytranaVyvanseFocalinKapvayProvigilDesoxynStratteraAdderall
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Available as
DaytranaVyvanseFocalinKapvayProvigilDesoxynStratteraAdderall
  • Liquid
  • Pill
  • Pill
  • Pill
  • Extended release
  • Extended release
  • Pill
  • Pill
  • Pill
  • Pill
  • Extended release
Used for
DaytranaVyvanseFocalinKapvayProvigilDesoxynStratteraAdderall
Risk factors for serious side effects
DaytranaVyvanseFocalinKapvayProvigilDesoxynStratteraAdderall
  • History of heart problems
  • History of drug abuse
  • History of psychotic episodes
  • History of bipolar disorder
  • History of Tourette's syndrome
  • Children
  • History of seizures
    • Use of MAO inhibitors
    Detailed Daytrana (methylphenidate) risks & warnings »
    • Taking monoamine oxidase inhibitors (MAOI) 14 days before starting
    • History of drug abuse
    • History of heart problems
    • History of psychotic episodes
    • History of Bipolar Disorder
    • Children ages 6 to 12
      Detailed Vyvanse (lisdexamfetamine) risks & warnings »
      • Taking monoamine oxidase inhibitors (MAOI) 14 days before starting
      • History of drug abuse
      • History of heart problems
      • History of psychotic episodes
      • History of Bipolar Disorder
      • Ages 7 to 10
      • History of seizures
            Detailed Focalin (dexmethylphenidate) risks & warnings »
            • Sudden discontinuation of medicine
            • Taking with alcohol
            • Taking other medicines that make you less alert
            • Age 65 years or older
            • Using other medicine(s) that slows the heart
              Detailed Kapvay (clonidine) risks & warnings »
              • Taking with alcohol
              • Taking other medicines that make you less alert
                • Current kidney problems
                • Current liver problems
                • History of heart problems
                • History of psychiatric disorder
                • History of bipolar disorder
                Detailed Provigil (modafinil) risks & warnings »
                • History of heart problems
                • History of drug abuse
                • History of psychotic episodes
                • History of Bipolar Disorder
                • Children
                • History of seizures
                • Women of childbearing age
                • Breast-feeding
                • Taking MAO inhibitors, insulin and other high blood pressure medicine
                Detailed Desoxyn (methamphetamine) risks & warnings »
                • Age below 18
                  • History of heart problems
                  • History of psychotic episodes
                  • History of Bipolar Disorder
                      • Starting Strattera (Atomoxetine) before puberty
                      Detailed Strattera (atomoxetine) risks & warnings »
                      • History of heart problems
                      • History of drug abuse
                      • Taking more than the prescribed dose
                      • History of high blood pressure
                      • History of psychotic episodes
                      • History of Bipolar Disorder
                      • Taking with alcohol or drugs
                      • Children ages 7 to 10
                      Detailed Adderall (dextroamphetamine / amphetamine) risks & warnings »
                      Pregnancy

                      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                      Interactions
                      DaytranaVyvanseFocalinKapvayProvigilDesoxynStratteraAdderall
                      No interactions related info.No interactions related info.No interactions related info.No interactions related info.
                      • Interacts with many other medications.
                      No interactions related info.No interactions related info.No interactions related info.
                      Alcohol
                      DaytranaVyvanseFocalinKapvayProvigilDesoxynStratteraAdderall
                      • Don't use alcohol or drugs while on this.
                      • Don't take it with alcohol or drugs.
                      • Don't take it with alcohol or drugs.
                      No alcohol related info.
                      • Don't drink alcohol with Provigil (Modafinil).
                      No alcohol related info.No alcohol related info.
                      • Don't take it with alcohol or drugs.
                      Kidneys and liver
                      DaytranaVyvanseFocalinKapvayProvigilDesoxynStratteraAdderall
                      No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
                      • Not a good choice if you have liver or kidney problems.
                      • Provigil (Modafinil) is broken down by the kidney and liver. If you have kidney or liver problems, you may need to use a lower dose to prevent more side effects.
                      No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
                      Sleep
                      DaytranaVyvanseFocalinKapvayProvigilDesoxynStratteraAdderall
                      • Don't take Daytrana (Methylphenidate) in the evening or you won't be able to sleep. If using the patch, put it on early in the morning to prevent insomnia.
                      No sleep related info.No sleep related info.
                      • Can cause drowsiness, headache, dizziness, and dry mouth.
                      No sleep related info.No sleep related info.No sleep related info.No sleep related info.
                      Weight
                      DaytranaVyvanseFocalinKapvayProvigilDesoxynStratteraAdderall
                      No weight related info.No weight related info.No weight related info.No weight related info.No weight related info.
                      • Only recommended for weight loss if other medications and plans haven't worked.
                      • If you're taking Desoxyn (Methamphetamine) for weight loss, take it 30 minutes before a meal. Desoxyn (Methamphetamine) can affect your concentration, so don't drive or do anything that requires concentration until you know how your body reacts to it.
                      No weight related info.
                      • Can cause blurry vision, loss of appetite, weight loss, headache, dry mouth, or anxious feelings.
                      Upsides and benefits
                      DaytranaVyvanseFocalinKapvayProvigilDesoxynStratteraAdderall
                      • Recommended as a first-choice medication to treat ADHD in both adults and children.
                      • The patch is convenient since it can be put on in the morning and doesn't need to be removed until 9 hours later.
                      • First-choice medication to treat ADHD.
                      • Vyvanse (Lisdexamfetamine) is used in combination with counseling or other non-drug therapies to treat ADHD.
                      • Usually dosed once a day, so parents don't need to send the medication with their children to school.
                      • The capsule can be taken whole, or opened into a glass of water or orange juice, or swallowed in a spoonful of yogurt.
                      • Focalin (Dexmethylphenidate) is used in combination with counseling or other non-drug therapies to treat ADHD.
                      • Available as a generic medication.
                      • Available in both an immediate-release form, which is given twice a day, and an extended-release form, which is given once a day.
                      • Capsules can be opened and sprinkled in water or applesauce for people who don't like swallowing pills.
                      • Can be used alone or together with a stimulant-type medicine to treat ADHD.
                      • In studies, it improved attention span and lowered hyperactivity and impulsivity in children and adolescents ages 6 to 17.
                      • Also treats blood pressure and some nervous system and psychiatric conditions.
                      • It's a non-amphetamine medicine that helps improve alertness.
                      • Available in a generic version.
                      • Effective in reducing excessive sleepiness in Shift-work Sleep Disorder.
                      • Doesn't negatively affect daytime sleep.
                      • Recommended as a first-choice medication to treat ADHD in both adults and children.
                      • Available as a generic, so it is cheaper than other medications to treat ADHD.
                      • One of the few medications used to treat ADHD that's not a stimulant.
                      • It isn't a controlled substance.
                      • Strattera (Atomoxetine) is used in combination with counseling or other non-drug therapies to treat ADHD.
                      • You usually only need to take it once a day.
                      • First-choice medication to treat ADHD.
                      • Adderall (Dextroamphetamine / Amphetamine) is used in combination with counseling or other non-drug therapies to treat ADHD.
                      • Available as a generic medication.
                      • Available in both immediate and extended release forms.
                      • The capsules can be opened, mixed in a spoonful of applesauce, and swallowed if you can't swallow the whole capsules.
                      Downsides and risks
                      DaytranaVyvanseFocalinKapvayProvigilDesoxynStratteraAdderall
                      • Need to change where you place the patch every day, otherwise your skin can become irritated.
                      • Need to avoid exposing the patch to heat sources such as heaters and electric blankets since the heat can cause the patch to unsafely release more drug than it was designed for.
                      • Can't use this if you have glaucoma.
                      • Not safe for children younger than 6 years.
                      • The patch is only available as brand name, so it can be expensive.
                      • Has to be taken in the morning, otherwise it can cause insomnia later that night.
                      • Not available as a generic medication, so it can be expensive.
                      • It's a controlled medication and should be locked up to prevent potential abuse.
                      • Not safe for people with a history of heart problems.
                      • Needs to be taken in the morning and early afternoon, or else it can cause insomnia later that night.
                      • It's a controlled medication and should be locked up to prevent potential abuse.
                      • Can lower blood pressure.
                      • The pill form can make some people sleepy, dizzy, and have dry mouth.
                      • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
                      • Provigil (Modafinil) can be habit-forming, so it's typically not used for long-term treatment.
                      • Interacts with many other medications.
                      • Taking Provigil (Modafinil) will make hormonal birth control less effective. You should definitely use additional forms of non-hormonal contraception.
                      • Not a good choice if you have liver or kidney problems.
                      • Only recommended for weight loss if other medications and plans haven't worked.
                      • Only used for short-term treatment because it is habit-forming.
                      • If you want to stop taking Desoxyn (Methamphetamine), talk to your doctor since stopping can cause withdrawal symptoms.
                      • Not safe for use in children younger than 12 years.
                      • It's a second-line medication used to treat ADHD. Other medications are usually tried first.
                      • It's only available as a brand name medication, so it can be expensive.
                      • Has to be taken in the morning and early afternoon, otherwise it can cause insomnia.
                      • It's a controlled medication and should be locked up to prevent potential abuse.
                      • Not safe for people with a history of heart problems.
                      • For schooled-aged children, the second dose will likely need to be given at school.
                      Tips from our pharmacists for people taking the medication
                      DaytranaVyvanseFocalinKapvayProvigilDesoxynStratteraAdderall
                      • Don't take Daytrana (Methylphenidate) in the evening or you won't be able to sleep. If using the patch, put it on early in the morning to prevent insomnia.
                      • Don't use alcohol or drugs while on this.
                      • Don't expose the patch to heaters or electric blankets since more drug can be unsafely released.
                      • Take the patch off after 9 hours and make sure you change the location of the patch every day.
                      • Keep it out of reach of children and store the medication in a safe place.
                      • Take Vyvanse (Lisdexamfetamine) early in the morning to prevent insomnia later that night.
                      • Avoid driving the first few days that you take Vyvanse (Lisdexamfetamine) until you know how your body reacts to it.
                      • Don't take it with alcohol or drugs.
                      • Store it in a locked area to prevent abuse.
                      • It can cause changes in your mood.
                      • Can raise your blood pressure and pulse, so it's not safe for people with heart problems.
                      • Store Focalin (Dexmethylphenidate) in a locked area to prevent abuse.
                      • Take it early in the morning to prevent insomnia later that night.
                      • It can cause changes in your mood and vision.
                      • Can raise your blood pressure and pulse, so it's not safe for people with heart problems.
                      • Don't take it with alcohol or drugs.
                      • The extended-release capsules can be opened and sprinkled on a small amount of applesauce.
                      • Common side effects include a decreased appetite, nausea, and insomnia.
                      • Can cause drowsiness, headache, dizziness, and dry mouth.
                      • For ADHD: Might take up to 2 weeks to see effects.
                      • For high blood pressure: Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
                      • If side effects don't go away, talk to your doctor about alternatives.
                      • Don't stop taking this medicine suddenly.
                      • Take Provigil (Modafinil) about an hour before you need to be fully alert.
                      • Taking caffeine with Provigil (Modafinil) can cause you to feel nervous, shaky, and have a faster heartbeat. Try limiting your caffeine intake.
                      • Until you know how Provigil (Modafinil) makes you feel, don't drive or perform any tasks that need you to be alert.
                      • You can experience withdrawal symptoms if you suddenly stop taking Provigil (Modafinil). Talk to your doctor before making any changes.
                      • Tell your doctor right away if you break out in a rash.
                      • Don't drink alcohol with Provigil (Modafinil).
                      • Don't take Desoxyn (Methamphetamine) in the evening or you won't be able to sleep.
                      • If you're taking Desoxyn (Methamphetamine) for weight loss, take it 30 minutes before a meal. Desoxyn (Methamphetamine) can affect your concentration, so don't drive or do anything that requires concentration until you know how your body reacts to it.
                      • Desoxyn (Methamphetamine) is only meant to be used for a few weeks since it can be habit-forming and lose its effectiveness.
                      • Can cause reduced appetite, insomnia, and restlessness.
                      • It can cause changes in sex drive.
                      • Can raise your blood pressure and pulse, so it's not safe for people with heart problems.
                      • It can also cause changes in your mood.
                      • Take it at the same time every day.
                      • Common side effects include decreased appetite, nausea, and constipation.
                      • The capsules can't be opened and need to be swallowed whole.
                      • Can cause blurry vision, loss of appetite, weight loss, headache, dry mouth, or anxious feelings.
                      • Don't take it with alcohol or drugs.
                      • Can cause trouble sleeping, so don't take it too close to bedtime.
                      • If using the extended-release version, the first dose is best taken right after waking up in the morning.
                      • Capsules can be opened and sprinkled on applesauce, which can then be swallowed without chewing.
                      Learn more
                      More about DaytranaSide effectsReviews & ratingsAlternativesFDA package insert
                      Have you used Daytrana (methylphenidate)?
                      Worth itNot sureNot worth it
                      More about VyvanseSide effectsReviews & ratingsFDA package insert
                      Have you used Vyvanse (lisdexamfetamine)?
                      Worth itNot sureNot worth it
                      More about FocalinSide effectsReviews & ratingsFDA package insert
                      Have you used Focalin (dexmethylphenidate)?
                      Worth itNot sureNot worth it
                      More about KapvaySide effectsReviews & ratingsFDA package insert
                      Have you used Kapvay (clonidine)?
                      Worth itNot sureNot worth it
                      More about ProvigilSide effectsReviews & ratingsFDA package insert
                      Have you used Provigil (modafinil)?
                      Worth itNot sureNot worth it
                      More about DesoxynSide effectsReviews & ratingsFDA package insert
                      Have you used Desoxyn (methamphetamine)?
                      Worth itNot sureNot worth it
                      More about StratteraSide effectsReviews & ratingsFDA package insert
                      Have you used Strattera (atomoxetine)?
                      Worth itNot sureNot worth it
                      More about AdderallSide effectsReviews & ratingsFDA package insert
                      Have you used Adderall (dextroamphetamine / amphetamine)?
                      Worth itNot sureNot worth it