Treats low estrogen and relieves menopause symptoms.
Our bottom line
The Delestrogen (Estradiol Valerate Injection) is a good once-a-month option for treating menopause symptoms and low estrogen, as long as you're comfortable with needles.
- You only need an injection once a month, which can be less of a hassle than pills, patches, creams, and gels.
- The Delestrogen (Estradiol Valerate Injection) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen (hot flashes, vaginal dryness, low energy, irritability).
- Good for people who don't want to take daily pills.
- Less side effects since lower amounts of estrogen is used compared to the oral pills.
- Lowers your risk of fractures by keeping your bones healthy. Make sure you also get enough calcium and Vitamin D.
- Can help relieve symptoms of prostate cancer or advanced breast cancer in some people.
- Requires injection with a needle, which can be difficult for some people.
- Increases your risk of endometrial and breast cancer.
- If you have your uterus, you have to use the Delestrogen (Estradiol Valerate Injection) with another hormone called progestin to lower your risk of uterine cancer.
- Increases your risk of developing blood clots and stroke.
- Can worsen your other health conditions, like high cholesterol, asthma, diabetes, fluid retention, and migraines.
- Can't be used in people with liver problems.
Side effect rates for Delestrogen (Estradiol Valerate Injection)
Risks and Warnings for Delestrogen (Estradiol Valerate Injection)Skip risks section. Skip to common concerns section.
- Higher risk if:
- › Using estrogen for more than one year
Vaginal bleeding after menopause can be a warning sign of uterus (endometrial) cancer, so let your doctor know if you notice any unusual bleeding. When estrogen is prescribed to women after menopause who still have a uterus, progestin should be used with it to lower the risk of cancer. Low-dose vaginal estrogen products are often a better choice than oral pills for women 65 years or older who have vaginal symptoms.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.