Prescription onlyLower-cost generic available

Depacon

(Valproate, Valproic Acid, Or Divalproex)

Prescription onlyLower-cost generic available
  • Pill
  • Extended release
  • Extended release capsule
  • Sprinkle
  • Liquid
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Prevents seizures and stabilizes mood.

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Our bottom line

Depacon (Valproate, Valproic Acid, Or Divalproex) is good long-term prevention for epilepsy, bipolar disorder, and migraines, but can cause weight gain.

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Upsides

  • Lowers the frequency of seizures, especially for people with absence, tonic-clonic, and complex partial seizures.
  • One of the first-line options to stabilize mood for people with bipolar disorder.
  • Helpful in preventing frequent migraine headaches.
People say this drug is:
93 reviews

Downsides

  • Can cause upset stomach, hair loss, weight gain, sleepiness, and tremor.
  • Can cause liver damage, so it's probably not safe if you already have liver problems.
  • Not safe to use if you're pregnant.
  • Requires routine blood tests to see how the medicine is affecting your body.

What to expect when you take Depacon (Valproate, Valproic Acid, Or Divalproex) for Seizures

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Side effect rates for Depacon (Valproate, Valproic Acid, Or Divalproex)

147 From clinical trials of Depakote / Adjunctive therapy for epilepsy, complex partial seizures
  • Nausea
  • Headache
  • Muscle weakness
  • Vomiting
  • Drowsiness
  • Dizziness
  • Tremor
  • Abdominal pain
  • Double vision
  • Diarrhea

Risks and Warnings for Depacon (Valproate, Valproic Acid, Or Divalproex)

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  • Depacon (Valproate, Valproic Acid, Or Divalproex) can cause birth defects. If you're considering having a baby, talk to your doctor about alternative medications.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Depacon (Valproate, Valproic Acid, Or Divalproex)

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Pregnancy
Food
  • Take with food to avoid upset stomach.
Kidneys and liver
  • Can cause liver damage, so it's probably not safe if you already have liver problems.
Weight
  • Can cause upset stomach, hair loss, weight gain, sleepiness, and tremor.
  • May cause hair loss and weight gain.
  • Noticeable weight gain around my gut. Had to start dieting and running on tread mill to combat the weight gain. Did not eliminate migraines, but made them less frequent and less intense. Now I can usually knock them out with a sumatriptan.
  • The side effects can be extreme: hand tremors, weight gain, memory issues, and others.