Depacon

(Valproate, Valproic Acid, Or Divalproex)

3.3/ 5 average rating with 97 reviewsforDepakote
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Prevents seizures and stabilizes mood.

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Our bottom line

Depacon (Valproate, Valproic Acid, Or Divalproex) is good long-term prevention for epilepsy, bipolar disorder, and migraines, but can cause weight gain.

Quick facts about Depakote
  • Drug class: Neurology
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (valproate, valproic acid, or divalproex)
Prices and discounts
Lowest price for 60 500mg capsules
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$293.48

Upsides

  • Lowers the frequency of seizures, especially for people with absence, tonic-clonic, and complex partial seizures.
  • One of the first-line options to stabilize mood for people with bipolar disorder.
  • Helpful in preventing frequent migraine headaches.

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What to expect from Depakote, on one page

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People’s experience with Depakote

97reviews so far. What do you think?

Downsides

  • Can cause upset stomach, hair loss, weight gain, sleepiness, and tremor.
  • Can cause liver damage, so it's probably not safe if you already have liver problems.
  • Not safe to use if you're pregnant.
  • Requires routine blood tests to see how the medicine is affecting your body.

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Get our free fact sheet

What to expect from Depakote, on one page

Download Fact Sheet
Prices and discounts
Lowest price for 60 500mg capsules
Determining your location...
$293.48
How it works

Depacon (Valproate, Valproic Acid, Or Divalproex) is an antiepileptic. Researchers don't know exactly how it works. It seems to increase the amount of GABA, a chemical that calms nerves in the brain.

Quick facts about Depakote
  • Drug class: Neurology
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (valproate, valproic acid, or divalproex)

Used for

Dosage forms

  • Pill
  • Extended release
  • Extended release capsule
  • Sprinkle
  • Liquid
People’s experience with Depakote

97reviews so far. What do you think?

What to expect when you take Depacon (Valproate, Valproic Acid, Or Divalproex) for Seizures

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Skip side effects section. Skip to risks and warnings section.

Side effect rates for Depacon (Valproate, Valproic Acid, Or Divalproex)

From 147 clinical trials of Depakote when taken for adjunctive therapy for epilepsy, complex partial seizures
  • Nausea
  • Headache
  • Asthenia
  • Vomiting
  • Somnolence
  • Tremor
  • Dizziness
  • Abdominal Pain
  • Diplopia
  • Diarrhea

Risks and Warnings for Depacon (Valproate, Valproic Acid, Or Divalproex)

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  • Depacon (Valproate, Valproic Acid, Or Divalproex) can cause birth defects. If you're considering having a baby, talk to your doctor about alternative medications.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Depacon (Valproate, Valproic Acid, Or Divalproex)

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Pregnancy
Food
  • Take with food to avoid upset stomach.
Kidneys and liver
  • Can cause liver damage, so it's probably not safe if you already have liver problems.
Weight
  • May cause hair loss and weight gain.
  • Can cause upset stomach, hair loss, weight gain, sleepiness, and tremor.
  • Reviewed Depakoteon 6/7/2017I gained 10 pounds every month I took depakote in odd places that I've never gained weight before. I basically became very broad (not in a good way) with a hump back. Felt like a zombie.
    29
    Woman
    A year or so
    Bipolar I disorder (manic)
  • Reviewed Depakoteon 8/8/2017Weight gain, 20 lbs in a year. Half of my hair thinned out after 4 months taking it. 1 year later it's finally starting to look decent but not like it was. Tried to change some eating habits and joined a gym. And my appetite is still not the same. I'm trying to get my dr to put me on something different
    27
    Woman
    A year or so
    Bipolar II disorder