Prescription onlyLower-cost generic availableClass: Neurology

Depacon

(valproate, valproic acid, or divalproex)

Prescription onlyLower-cost generic availableClass: Neurology
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Prevents seizures and stabilizes mood.

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Our bottom line

Depacon (Valproate, Valproic Acid, Or Divalproex) is good long-term prevention for epilepsy, bipolar disorder, and migraines, but can cause weight gain.

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Upsides

  • Lowers the frequency of seizures, especially for people with absence, tonic-clonic, and complex partial seizures.
  • One of the first-line options to stabilize mood for people with bipolar disorder.
  • Helpful in preventing frequent migraine headaches.
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Downsides

  • Can cause upset stomach, hair loss, weight gain, sleepiness, and tremor.
  • Can cause liver damage, so it's probably not safe if you already have liver problems.
  • Not safe to use if you're pregnant.
  • Requires routine blood tests to see how the medicine is affecting your body.
How it works

Depacon (Valproate, Valproic Acid, Or Divalproex) is an antiepileptic. Researchers don't know exactly how it works. It seems to increase the amount of GABA, a chemical that calms nerves in the brain.

What to expect when you take Depacon (valproate, valproic acid, or divalproex) for Seizures

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Side effect rates for Depacon (valproate, valproic acid, or divalproex)

147 From clinical trials of Depakote / Adjunctive therapy for epilepsy, complex partial seizures
  • Nausea
  • Headache
  • Muscle weakness
  • Vomiting
  • Drowsiness
  • Dizziness
  • Tremor
  • Abdominal pain
  • Double vision
  • Diarrhea

Risks and Warnings for Depacon (valproate, valproic acid, or divalproex)

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  • Depacon (Valproate, Valproic Acid, Or Divalproex) can cause birth defects. If you're considering having a baby, talk to your doctor about alternative medications.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Depacon (valproate, valproic acid, or divalproex)

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Pregnancy
Food
  • Take with food to avoid upset stomach.
Kidneys and liver
  • Can cause liver damage, so it's probably not safe if you already have liver problems.
Weight
  • Can cause upset stomach, hair loss, weight gain, sleepiness, and tremor.
  • May cause hair loss and weight gain.
  • The side effects can be extreme: hand tremors, weight gain, memory issues, and others.