Prescription onlyLower-cost generic available

Depacon Alternatives

(Valproate, Valproic Acid, Or Divalproex)

  • Pill
  • Extended release
  • Extended release capsule
  • Sprinkle
  • Liquid
Back to: Full Site Navigation

Compare Depacon (Valproate, Valproic Acid, Or Divalproex) to alternatives

These medications are comparable to Depacon (Valproate, Valproic Acid, Or Divalproex) or used for similar purposes.

Depacon
(Valproate, Valproic Acid, Or Divalproex)

Lamictal
(Lamotrigine)

Tegretol
(Carbamazepine)

Qudexy Xr
(Topiramate)

Inderal
(Propranolol)

Prevents seizures and stabilizes mood. Depacon (Valproate, Valproic Acid, Or Divalproex) is good long-term prevention for epilepsy, bipolar disorder, and migraines, but can cause weight gain.Prevents seizures and stabilizes mood. Lamictal (Lamotrigine) is most useful for treating severe seizure disorders, and for bipolar disorder with more depression symptoms than manic symptoms. Just be careful to increase your dose slowly to avoid skin rash.Prevents seizures, stabilizes mood, and relieves nerve pain. Tegretol (Carbamazepine) is useful for preventing seizures and relieving certain types of nerve pain, but interacts with many drugs.Prevents seizures and migraine headaches. Qudexy Xr (Topiramate) is useful for preventing seizures and migraines, and doesn't require blood tests while you're on it.Lowers blood pressure and controls heart rate. Inderal (Propranolol) is good for treating many heart problems and other problems in the body, but it has more side effects than other beta blockers. You can't miss doses.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Loading pricing data...
Loading pricing data...
Loading pricing data...
Loading pricing data...
Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.376344086021505Depakote
Reviews for Depacon (Valproate, Valproic Acid, Or Divalproex)
46%
of people say Depacon (Valproate, Valproic Acid, Or Divalproex) is worth it
39%
say it works well
27%
say it's a big hassle
Reviews for Lamictal (Lamotrigine)
67%
+21% vs. Depacon (Valproate, Valproic Acid, Or Divalproex)
58%
+19% vs. Depacon (Valproate, Valproic Acid, Or Divalproex)
19%
+8% vs. Depacon (Valproate, Valproic Acid, Or Divalproex)
Reviews for Tegretol (Carbamazepine)
58%
+12% vs. Depacon (Valproate, Valproic Acid, Or Divalproex)
42%
+3% vs. Depacon (Valproate, Valproic Acid, Or Divalproex)
21%
+6% vs. Depacon (Valproate, Valproic Acid, Or Divalproex)
Reviews for Qudexy Xr (Topiramate)
54%
+8% vs. Depacon (Valproate, Valproic Acid, Or Divalproex)
52%
+13% vs. Depacon (Valproate, Valproic Acid, Or Divalproex)
33%
6% vs. Depacon (Valproate, Valproic Acid, Or Divalproex)
Reviews for Inderal (Propranolol)
62%
+16% vs. Depacon (Valproate, Valproic Acid, Or Divalproex)
58%
+19% vs. Depacon (Valproate, Valproic Acid, Or Divalproex)
17%
+10% vs. Depacon (Valproate, Valproic Acid, Or Divalproex)
Side effects
DepakoteLamictalTegretolTopamaxPropranolol
  • Nausea 34%
  • Muscle weakness 20%
  • Vomiting 20%
  • Abdominal pain 17%
  • Dizziness 12%
  • Headache 10%
  • Double vision 7%
  • Involuntary eye movement 7%
  • Lack of muscle coordination 7%
  • Accidental injury 6%
More Depakote side effects »
  • Double vision 41%
  • Dizziness 27%
  • Lack of muscle coordination 18%
  • Blurred vision 15%
  • Nausea 14%
  • Vomiting 14%
  • Headache 10%
  • Inflammation inside the nose 5%
  • Sleep difficulty 4%
  • Incoordination 4%
More Lamictal side effects »
  • Dizziness 32%
  • Drowsiness 19%
  • Nausea 19%
  • Vomiting 15%
  • Itching 6%
  • Constipation 5%
  • Dry mouth 5%
  • Muscle weakness 4%
  • Blurred vision 4%
  • Rash 3%
More Tegretol side effects »
  • Tingling sensation 45%
  • Slowed-down thinking and movements 19%
  • Dizziness 17%
  • Drowsiness 17%
  • Fatigue 17%
  • Change in taste 14%
  • Difficulty with concentration/attention 13%
  • Nervousness 12%
  • Difficulty with memory 11%
  • Vision abnormal 11%
More Topamax side effects »
  • Dizziness 5%
  • Fatigue 4%
More Propranolol side effects »
How it works
DepakoteLamictalTegretolTopamaxPropranolol
Depacon (Valproate, Valproic Acid, Or Divalproex) is an antiepileptic. Researchers don't know exactly how it works. It seems to increase the amount of GABA, a chemical that calms nerves in the brain.Lamictal (Lamotrigine) is an antiepileptic. Researchers don't know exactly how it works, but it seems to calm nerve activity in the brain.Tegretol (Carbamazepine) is an antiepileptic. Researchers don't know exactly how it works, but it seems to block certain kinds of nerve activity to reduce seizures and pain.Qudexy Xr (Topiramate) is an antiepileptic. Researchers don't know exactly how it works, but it seems to affect multiple parts of the brain to control seizures and migraines.Inderal (Propranolol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
DepakoteLamictalTegretolTopamaxPropranolol
AnticonvulsantPrescription only
AnticonvulsantPrescription only
AnticonvulsantPrescription only
AnticonvulsantPrescription only
Antihypertensive
Beta blocker
Prescription only
Available as
DepakoteLamictalTegretolTopamaxPropranolol
  • Pill
  • Extended release
  • Extended release capsule
  • Sprinkle
  • Liquid
  • Pill
  • Extended release
  • Chewable tablet
  • Dissolving tablet
  • Pill
  • Extended release
  • Chewable tablet
  • Oral suspension
  • Pill
  • Extended release capsule
  • Pill
  • Extended release
  • Liquid
Used for (click to learn more)
DepakoteLamictalTegretolTopamaxPropranolol
How well it works for depression
The free Iodine Start program helps people track how well they are improving, and find the right antidepressant faster.
The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Depacon (Valproate, Valproic Acid, Or Divalproex)The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Lamictal (Lamotrigine)The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Tegretol (Carbamazepine)The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Qudexy Xr (Topiramate)The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Inderal (Propranolol)
Risk factors for serious side effects
DepakoteLamictalTegretolTopamaxPropranolol
    • Children under age 2
    • History of metabolic disorders
      • History of depression
        • History of metabolic disorders
        • People also taking Topamax
        • People also taking Topamax
          • Stopping Depacon (Valproate, Valproic Acid, Or Divalproex) suddenly
          Detailed Depacon (Valproate, Valproic Acid, Or Divalproex) risks & warnings »
          Coming soon.Coming soon.Coming soon.Coming soon.
          Pregnancy category
          DepakoteLamictalTegretolTopamaxPropranolol
          DFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          DFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          DFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.
          Food
          • Take with food to avoid upset stomach.
          • Take with food to avoid upset stomach.
          No specific food-related info.No specific food-related info.No specific food-related info.
          Kidneys and liver
          No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.
          • A few people will get kidney stones.
          No specific kidneys and liver-related info.
          Sex
          No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.No specific sex-related info.
          Sleep
          No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.
          Weight
          • Can cause upset stomach, hair loss, weight gain, sleepiness, and tremor.
          • May cause hair loss and weight gain.
          No specific weight-related info.No specific weight-related info.
          • Can cause sleepiness, speech problems, tingling sensations, and weight loss.
          No specific weight-related info.
          Upsides and benefits
          DepakoteLamictalTegretolTopamaxPropranolol
          • Lowers the frequency of seizures, especially for people with absence, tonic-clonic, and complex partial seizures.
          • One of the first-line options to stabilize mood for people with bipolar disorder.
          • Helpful in preventing frequent migraine headaches.
          • Effective at lowering the frequency of seizures in people with epilepsy or Lennox-Gestaut syndrome. Typically used together with other medications for severe seizure disorders.
          • Works best for partial, tonic-clonic, and absence seizures.
          • A first-line treatment for bipolar disorder. Effective long-term treatment for stabilizing mood. Prevents both depressive and manic episodes, but the effect is greater for preventing depression.
          • Doesn't require routine blood tests.
          • Lowers the frequency of seizures, especially for people with tonic-clonic and partial seizures.
          • First-line option for trigeminal neuralgia (nerve pain involving the face, head, and neck), and can relieve other types of nerve pain.
          • May be helpful in stabilizing mood for people with bipolar disorder.
          • Used on its own or with other antiepileptic medicines to lower the frequency of seizures, especially for people with tonic-clonic or partial seizures, or Lennox-Gestaut syndrome.
          • Doesn't need routine blood tests.
          • Helpful in preventing frequent migraine headaches.
          • A first-choice treatment to prevent chest pain (angina).
          • A first-choice treatment for heart failure, heart attack, heart valve disorders, and abnormal heart rhythm.
          • Also treats and prevents many non-heart problems, such as tremors, anxiety, migraines, and liver disease symptoms.
          Downsides and risks
          DepakoteLamictalTegretolTopamaxPropranolol
          • Can cause upset stomach, hair loss, weight gain, sleepiness, and tremor.
          • Can cause liver damage, so it's probably not safe if you already have liver problems.
          • Not safe to use if you're pregnant.
          • Requires routine blood tests to see how the medicine is affecting your body.
          • Can cause double vision, dizziness, sleepiness, and headache.
          • Has the risk of a rare but life-threatening rash.
          • Can make hormonal birth control less effective.
          • Might be less effective than other medicines for treating manic episodes (acute mania) in people with bipolar disorder.
          • Interacts with many other medicines and supplements.
          • Higher risk of skin reactions compared to other antiepileptic medicines, ranging from mild to life-threatening rash.
          • Can cause blurry vision, dizziness, and upset stomach.
          • Not safe to use if you're pregnant.
          • Requires routine blood tests to see how the medicine is affecting your body.
          • Can cause sleepiness, speech problems, tingling sensations, and weight loss.
          • A few people will get kidney stones.
          • Not safe to use if you're pregnant.
          • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
          • Has more side effects than some beta blockers because it crosses into the brain and central nervous system.
          • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
          • Can hide symptoms of low blood sugar if you're diabetic.
          • You can't miss doses. Stopping Propranolol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
          Tips from our pharmacists for people taking the medication
          DepakoteLamictalTegretolTopamaxPropranolol
          • May cause hair loss and weight gain.
          • Different versions of Depakote have different dosing. Be careful.
          • For the first week, avoid activities that require you to be alert.
          • Don't use if pregnant.
          • Requires routine blood tests.
          • Take with food to avoid upset stomach.
          • Report confusion, persistent abdominal pain, yellowing of eyes/skin, or easy bruising to your doctor.
          • Takes 3 to 4 weeks to feel full effects on mood.
          • Follow dose adjustments set by your doctor to minimize skin rash.
          • Report rash, blurry vision, fever, persistent headache, or neck stiffness to your doctor.
          • Makes hormonal birth control less effective.
          • Takes 4 to 6 weeks to feel full effects on mood.
          • Take with food to avoid upset stomach.
          • Report skin rashes or blistering immediately.
          • Takes up to 5 weeks to feel full effects on mood.
          • For the first week, avoid activities that require you to be alert.
          • Don't use if pregnant.
          • Requires routine blood tests.
          • Report confusion, persistent abdominal pain, yellowing of eyes/skin, or easy bruising to your doctor.
          • Can cause tingling skin sensations and reduced appetite.
          • Report any confusion, decreased sweating, fever, or changes in behavior or vision.
          • For the first week, avoid activities that require you to be alert.
          • Don't use if pregnant.
          • Takes 3 to 4 weeks to feel full effects on mood.
          • Can cause dizziness in the first few days.
          • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
          • Can cause insomnia and fatigue.
          • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
          • Don't stop taking this medicine suddenly.
          Learn more
          More about DepakoteSide effectsReviews & ratingsAlternativesFDA package insert
          More about LamictalSide effectsReviews & ratingsFDA package insert
          More about TegretolSide effectsReviews & ratingsFDA package insert
          More about TopamaxSide effectsReviews & ratingsFDA package insert
          More about PropranololSide effectsReviews & ratingsFDA package insert