Prescription onlyClass: Gastrointestinal



Prescription onlyClass: Gastrointestinal
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Treats heartburn and ulcers.

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Our bottom line

Dexilant (Dexlansoprazole) is an effective medicine to treat heartburn and ulcers, but can be expensive.

Price and discounts
Best available price for 30 (60mg) capsules of dexlansoprazole


  • Relieves heartburn symptoms and heals ulcers better than other stomach medicines, such as Pepcid, Tagamet, and Zantac.
  • Lasts longer than other similar stomach medicines. Most people take it once a day.
  • Your body won't develop a tolerance to Dexilant (Dexlansoprazole), so it'll work the same way as long as you need to keep taking it.
  • Once heartburn symptoms are treated, a low dose of Dexilant (Dexlansoprazole) can be taken daily.
People say this drug is:
73 reviews


  • Taking Dexilant (Dexlansoprazole) in high doses or for longer than 1 year can increase the risk for bone fractures, especially if you already have osteoporosis (weak bones).
  • Many drugs can interact with Dexilant (Dexlansoprazole), so talk to your doctor or pharmacist before starting any new medicines.
  • There's no generic version available, so it can be expensive.
How it works

Dexilant (Dexlansoprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.

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Side effect rates for Dexilant (dexlansoprazole)

  • Diarrhea
  • Abdominal pain
  • Nausea
  • Ear, nose, or throat infection
  • Vomiting
  • Passing gas

Risks and Warnings for Dexilant (dexlansoprazole)

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  • Heartburn and feelings of upset stomach can be warning signs of a more serious stomach problem or cancer. If you need to take Dexilant (Dexlansoprazole) for 2 weeks or more go see a doctor. It's safest to get checked out to make sure you do not have a serious stomach condition.

Common concerns from people taking Dexilant (dexlansoprazole)

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  • I have to take this every day. It really helps, but the cost is so much. Been trying to see how I can afford it.
  • There's a discount card from the manufacturer that if used with insurance brings the price to about $50, which is what I pay.
  • Dexilant worked very well for me however it was cost inhibitive. My Dr. put me on Protonix 40 mg. It took about two weeks to effective. It works almost as well. The difference between $250 a month for Dexilant or $10 a month for Protonix
  • Many drugs can interact with Dexilant (Dexlansoprazole), so talk to your doctor or pharmacist before starting any new medicines.
  • Take before acidic dinner/alcohol. Do not take with other meds in morning. Cancels out antidepressants.
  • Take Dexilant (Dexlansoprazole) with or without food. It can work better for some people if it's taken 30 minutes before a meal.
  • You can't take iron supplements with it so make sure you're getting enough with the food you eat.
  • Call your doctor if you have watery stools, stomach pain, or a fever because it could be a sign of a serious infection.
  • The medicine worked almost immediately at eliminating the acid causing blisters in my throat and pain in my stomach. It also helped my digestion. Less gas and healthier stools. After about a week of taking it I am so anxious and nervous. I feel like I drank 10 cups of coffee and every sound and touch is so irritating. I couldn't function I was so on-edge and angry.