Prescription onlyClass: Pain

Zorvolex

(diclofenac)

Prescription onlyClass: Pain
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Treats arthritis pain and swelling.

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Our bottom line

Zorvolex (Diclofenac) is an okay medication used to treat pain and swelling caused by arthritis. However, because of the risk of heart attack, you should limit the amount you take.

Upsides

  • Clinical studies show that Zorvolex (Diclofenac) is better at relieving arthritis pain than acetaminophen (Tylenol).
  • Can be used as needed to treat pain and swelling.
  • Available as a generic.
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Downsides

  • You should avoid alcohol while on Zorvolex (Diclofenac) since it can increase your risk of stomach issues.
  • If you're taking it on a regular basis, you'll need to get labs done to make sure your liver and kidneys aren't being affected.
How it works

Zorvolex (Diclofenac) is a non-steroidal anti-inflammatory drug (NSAID). It stops your body from making chemicals that cause inflammation and pain.

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Used for
  • Osteoarthritis pain
Dosage forms
  • Pill
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Side effect rates for Zorvolex (diclofenac)

305 From clinical trials of Diclofenac / Osteoarthritis pain (35 mg)
  • Headache
  • Ear, nose, or throat infection
  • Nausea
  • Urinary tract infection
  • Diarrhea
  • Nausea
  • Common cold
  • Diarrhea
  • Arthritis
  • Sinus inflammation

Risks and Warnings for Zorvolex (diclofenac)

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    • Higher risk if:
    • History of heart problems
    • High blood pressure
    • High cholesterol
    • Diabetes
    • Being overweight or obese
    • Smoking

    Zorvolex (Diclofenac) can increase your chance of having blood clots, heart attack, or stroke. Take the lowest dose for the shortest time possible to lower your risk. Never take Zorvolex (Diclofenac) during the first two weeks after having heart surgery.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Zorvolex (diclofenac)

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Pregnancy
Alcohol
  • Don't drink alcohol while using Zorvolex (Diclofenac).
  • You should avoid alcohol while on Zorvolex (Diclofenac) since it can increase your risk of stomach issues.
Food
  • Take it with food to avoid getting diarrhea.
  • Make sure you take with food
Kidneys and liver
  • Zorvolex (Diclofenac), and similar medications in the NSAID family, can lower kidney function or cause permanent kidney damage. Taking the lowest dose for the shortest amount of time necessary can lower your risk of kidney problems. It's important to get lab tests to check your kidney function periodically if you use Zorvolex (Diclofenac) for long periods of time.
  • Have your liver checked every 3 months to begin with to see if affects you.
Pain
  • Can cause swelling in your legs, abdominal pain, constipation, diarrhea, and an upset stomach.
  • Clinical studies show that Zorvolex (Diclofenac) is better at relieving arthritis pain than acetaminophen (Tylenol).
  • Can be used as needed to treat pain and swelling.
  • I find it good for very short term pain, I wouldn't take it for more than 3 or 4 days I case there is risk
  • This medication works so good I cut the use of my other pain meds
  • Reduces inflamation but doesnt remove pain, side effects really scary
Sleep
  • I take it when needed about an hour before bed and have been able to sleep through the night without the knee pain keeping me awake. I have never experienced any side effects ... maybe because I am asleep.