Prescription onlyLower-cost generic available

Diflucan

(Fluconazole)

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Kills yeast and fungus.

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Prescription onlyLower-cost generic available

Our pharmacists’ bottom line

Diflucan (Fluconazole) is a quick, cheap, and convenient way to get rid of a yeast infection. (It's used for other kinds of fungal infections, too.) You have to avoid alcohol, though.

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  • Available in generic.
  • For women with yeast infections, you only have to take one pill one time.
  • You have to avoid alcohol while on this medication.
  • You have to avoid having sex for at least a week after you take Fluconazole.
  • Can interact with birth control pills, so you'll need to use condoms or other barriers if you do have sex.

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Side effects for Diflucan (Fluconazole)

Manufacturers don’t say how common these side effects are

  • Liver problems

What to expect when you take Diflucan (Fluconazole)

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Tips from our pharmacists
  • If you're taking this for a vaginal yeast infection, you only have to take it once. Don't have sex for at least 7 days.
  • For other fungal infections, take it exactly how your doctor tells you to.
  • Don't drink alcohol when you take this medication.
  • If you're on birth control pills, Fluconazole can make them less effective. Consider using another method (condoms, diaphragms) along with the pills.
  • Can cause nausea, vomiting, diarrhea and headache.

Risks and Warnings for Diflucan (Fluconazole)

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  • There have been reports of people on Diflucan (Fluconazole) who have suffered liver damage sometimes to the point of liver transplant. This has been rare, and only happened when people are taking this for an extended amount of time. If you notice yellowing of the eyes or skin, dark urine, or abdominal pain, talk to your doctor.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Diflucan (Fluconazole)

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The FDA category for this medication is D. It is advised that you: Weigh risks vs. benefits
Pregnancy
Alcohol
  • Upsides and downsides from our pharmacists
  • You have to avoid alcohol while on this medication.
  • Tips from our pharmacists
  • Don't drink alcohol when you take this medication.
Sex
  • Upsides and downsides from our pharmacists
  • You have to avoid having sex for at least a week after you take Fluconazole.
  • Can interact with birth control pills, so you'll need to use condoms or other barriers if you do have sex.
  • Tips from our pharmacists
  • If you're taking this for a vaginal yeast infection, you only have to take it once. Don't have sex for at least 7 days.