Prescription onlyLower-cost generic availableClass: Cardiovascular

Cardizem Alternatives

(diltiazem)

Prescription onlyLower-cost generic availableClass: Cardiovascular
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Compare Cardizem (diltiazem) to alternatives

These medications are comparable to Cardizem (diltiazem) or used for similar purposes.

Cardizem
(diltiazem)

Lopressor
(metoprolol tartrate)

Minipress
(prazosin)

Coreg
(carvedilol)

Norvasc
(amlodipine)

Procardia
(nifedipine)

Microzide
(hydrochlorothiazide )

Zestoretic
(lisinopril / hydrochlorothiazide)

Zestril
(lisinopril)

Diovan
(valsartan)

Catapres
(clonidine)

Calan
(verapamil)

Lowers blood pressure and controls heart rate. Diltiazem works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding alcohol. You can't miss doses, and you might get persistent swelling.Lowers blood pressure and controls heart rate. Lopressor (metoprolol tartrate) lowers high blood pressure, controls chest pain, and helps treat heart failure and heart attack. You need to take it with food and can't miss a dose.Lowers blood pressure and makes it easier to urinate. Prazosin is used mostly to make urination easier for men with an enlarged prostate, but it can cause dizziness.Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.Lowers blood pressure. Norvasc (Amlodipine) works well to lower blood pressure and prevent chest pain. You can't miss doses, and you might get persistent swelling.Lowers blood pressure and controls heart rate. Nifedipine works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding grapefruit. You can't miss doses, and you might get persistent swelling.Removes water from the body, which lowers blood pressure. Microzide (hydrochlorothiazide (HCTZ)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Lowers blood pressure. Lisinopril/hydrochlorothiazide is a good 2-in-1 blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Diovan (Valsartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.Lowers blood pressure. Catapres (Clonidine) is a good addition if you need more than one medicine to control your blood pressure, but it has a lot of side effects. You can't miss doses.Lowers blood pressure and controls heart rate. Verapamil works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding alcohol. You can't miss doses, and you might get persistent swelling.
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Best available price for 90 (30mg) tablets of diltiazem
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.71Diltiazem
Reviews for Diltiazem
52%
of people (All ages) say Diltiazem is worth it
49%
say it works well
16%
say it's a big hassle
105 reviews
Have you used Cardizem (diltiazem)?
Worth itNot sureNot worth it
Reviews for Lopressor
62%
-10% worse vs. Diltiazem
47%
+2% better vs. Diltiazem
15%
-1% worse vs. Diltiazem
464 reviews
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
Reviews for Prazosin
46%
+6% better vs. Diltiazem
29%
+20% better vs. Diltiazem
15%
-1% worse vs. Diltiazem
Have you used Minipress (prazosin)?
Worth itNot sureNot worth it
Reviews for Coreg
53%
-1% worse vs. Diltiazem
46%
+3% better vs. Diltiazem
18%
+2% better vs. Diltiazem
406 reviews
Have you used Coreg (carvedilol)?
Worth itNot sureNot worth it
Reviews for Norvasc
58%
-6% worse vs. Diltiazem
50%
-1% worse vs. Diltiazem
15%
-1% worse vs. Diltiazem
443 reviews
Have you used Norvasc (amlodipine)?
Worth itNot sureNot worth it
Reviews for Nifedipine
42%
+10% better vs. Diltiazem
31%
+18% better vs. Diltiazem
46%
+30% better vs. Diltiazem
Have you used Procardia (nifedipine)?
Worth itNot sureNot worth it
Reviews for hydrochlorothiazide
47%
+5% better vs. Diltiazem
31%
+18% better vs. Diltiazem
16%
Same vs. Diltiazem
139 reviews
Have you used Microzide (hydrochlorothiazide )?
Worth itNot sureNot worth it
Reviews for Zestoretic
51%
+1% better vs. Diltiazem
40%
+9% better vs. Diltiazem
17%
+1% better vs. Diltiazem
294 reviews
Have you used Zestoretic (lisinopril / hydrochlorothiazide)?
Worth itNot sureNot worth it
Reviews for Lisinopril
61%
-9% worse vs. Diltiazem
51%
-2% worse vs. Diltiazem
14%
-2% worse vs. Diltiazem
687 reviews
Have you used Zestril (lisinopril)?
Worth itNot sureNot worth it
Reviews for Diovan
65%
-13% worse vs. Diltiazem
54%
-5% worse vs. Diltiazem
15%
-1% worse vs. Diltiazem
431 reviews
Have you used Diovan (valsartan)?
Worth itNot sureNot worth it
Reviews for Catapres
42%
+10% better vs. Diltiazem
33%
+16% better vs. Diltiazem
35%
+19% better vs. Diltiazem
Have you used Catapres (clonidine)?
Worth itNot sureNot worth it
Reviews for Calan
35%
+17% better vs. Diltiazem
33%
+16% better vs. Diltiazem
21%
+5% better vs. Diltiazem
Have you used Calan (verapamil)?
Worth itNot sureNot worth it
Side effects
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
  • Swelling due to excess fluid 5%
  • Headache 5%
  • Dizziness 4%
  • Muscle weakness 3%
  • First degree av block 2%
  • Abnormally slow heartbeat 2%
More Diltiazem side effects »
  • Tiredness 10%
  • Dizziness 10%
  • Low mood disorder 5%
  • Diarrhea 5%
  • Itching or skin rash 5%
  • Shortness of breath 3%
  • Slowed heart rate 3%
  • Low blood pressure 4%
More Lopressor side effects »
  • Dizziness 10%
  • Headache 8%
  • Drowsiness 8%
  • Lack of energy 7%
  • Weakness 7%
  • Heart pounding or racing sensation 5%
  • Nausea 5%
More Prazosin side effects »
  • Dizziness 13%
  • Fatigue 2%
  • High blood sugar 4%
  • Diarrhea 6%
  • Weight increase 3%
  • Nausea 4%
  • Abnormally slow heartbeat 8%
  • Low blood pressure 6%
  • Headache 1%
More Coreg side effects »
  • Swelling due to excess fluid 2%
  • Dizziness 1%
  • Heart pounding or racing sensation 5%
  • Flushing 3%
  • Fatigue 2%
  • Nausea 1%
  • Abdominal pain 2%
  • Drowsiness 2%
More Norvasc side effects »
  • Dizziness, lightheadedness, giddiness 12%
  • Flushing 17%
  • Headache 3%
  • Weakness 2%
  • Nausea, heartburn 3%
  • Muscle cramps, tremor 5%
  • Leg or ankle swelling 6%
  • Nervousness, mood changes 3%
  • Heart pounding or racing sensation 2%
  • Dyspnea, cough, wheezing 3%
More Nifedipine side effects »

The hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about hydrochlorothiazide side effects »
  • Dizziness 6%
  • Headache 3%
  • Cough 3%
  • Fatigue 3%
  • Orthostatic effects 2%
  • Diarrhea 1%
  • Upper respiratory infection 2%
  • Muscle cramps 2%
  • Muscle weakness 1%
More Zestoretic side effects »
  • Headache 4%
  • Dizziness 4%
  • Cough 3%
  • Low blood pressure 4%
  • Chest pain 2%
  • Kidney damage 10%
  • Fainting 7%
  • High potassium 6%
More Lisinopril side effects »
  • Cough 1%
  • Viral infection 1%
  • Fatigue 1%
  • Abdominal pain 1%
  • Dizziness 8%
  • Low blood pressure 5%
  • Diarrhea 1%
  • Joint pain 1%
  • Back pain 1%
  • Dizziness, postural 1%
More Diovan side effects »
  • Redness/itching / pruritis 26%
  • Dry mouth 25%
  • Drowsiness 12%
  • Skin blistering 7%
  • Fatigue 6%
  • Headache 5%
  • Skin or nail darkening 5%
  • Allergic contact sensitization 5%
  • Burning 3%
  • Lack of energy 3%
More Catapres side effects »
  • Constipation 7%
  • Dizziness 3%
  • Nausea 3%
  • Low blood pressure 3%
  • Headache 2%
  • Swelling due to excess fluid 2%
  • Chf and pulmonary edema 2%
  • Fatigue 2%
  • Lack of energy 3%
  • Indigestion 3%
More Calan side effects »
How it works
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
Diltiazem is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Lopressor (metoprolol tartrate) is a beta blocker. It lowers blood pressure by slowing your heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Prazosin is a selective alpha blocker. It lowers blood pressure by relaxing blood vessels. It also relaxes the urethra and prostate, which makes it easier to urinate.Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Norvasc (Amlodipine) is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Nifedipine is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Microzide (hydrochlorothiazide (HCTZ)) is a thiazide diuretic (water pill) that makes you urinate more. It works in the kidneys to remove extra water and certain electrolytes, while lowering blood pressure and reducing swelling.Lisinopril/hydrochlorothiazide is a combination medicine. Lisinopril (an ACE inhibitor) lowers blood pressure by making blood vessels relax. Hydrochlorothiazide (a diuretic or water pill) lowers blood pressure and swelling by removing extra fluid from your body.Zestril (lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Diovan (Valsartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Catapres (Clonidine) is an alpha-2 agonist. It works in the brain to tell your blood vessels to relax, and it lowers the activity of certain stress hormones. This lowers blood pressure.Verapamil is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.
Type of medication
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
Prescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription onlyPrescription only
Available as
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
  • Pill
  • Extended release
  • Extended release capsule
  • Pill
  • Pill
  • Pill
  • Extended release
  • Pill
  • Pill
  • Extended release
  • Pill
  • Pill
  • Pill
  • Liquid
  • Pill
  • Pill
  • Extended release
  • Patch
  • Pill
  • Extended release
  • Delayed release capsule
Used for
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
Risk factors for serious side effects
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
  • Taking digoxin or beta-blockers at the same time
  • History of liver disease
Detailed Cardizem (diltiazem) risks & warnings »
  • Suddenly stopping Lopressor (metoprolol tartrate)
  • Coronary artery disease
  • Diabetes
  • Heart failure
  • Major surgery requiring anesthesia
Detailed Lopressor (metoprolol tartrate) risks & warnings »
  • Age 65 years or older
Detailed Minipress (prazosin) risks & warnings »
  • Abrupt discontinuation of Coreg (Carvedilol)
  • Congestive heart failure
  • Increasing the dose of Coreg (Carvedilol)
  • Diabetes
  • Major surgery requiring anesthesia
Detailed Coreg (carvedilol) risks & warnings »
  • Age 65 years or older
  • History of heart problems
  • Liver disease
  • History of blood vessel disease
  • History of heart failure
Detailed Norvasc (amlodipine) risks & warnings »
  • Taking anti-inflammatories, acid reducers in the stomach, anticholinergics, laxatives, levothyroxine
  • History of intestinal surgery
  • Taking beta-blockers
  • Severe coronary artery disease.
  • History of cirrhosis
Detailed Procardia (nifedipine) risks & warnings »
  • Current electrolyte imbalance
  • Lower kidney function
  • Dehydration
  • History of sulfa allergies
  • History of gout
Detailed Microzide (hydrochlorothiazide ) risks & warnings »
  • Women of childbearing age
  • African descent
  • People requiring high flux dialysis
  • History of kidney disease
  • Current kidney problems
Detailed Zestoretic (lisinopril / hydrochlorothiazide) risks & warnings »
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicines that increase potassium
  • Use of salt substitutes
Detailed Zestril (lisinopril) risks & warnings »
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed Diovan (valsartan) risks & warnings »
  • Sudden discontinuation of medicine
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 years or older
  • Using other medicine(s) that slows the heart
Detailed Catapres (clonidine) risks & warnings »
  • Severe left ventricular dysfunction (ejection fraction <30%)
  • Taking beta-blockers
  • History of liver disease
  • History of kidney disease
Detailed Calan (verapamil) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
  • Interacts with the cholesterol medicine Simvastatin.
No interactions related info.No interactions related info.No interactions related info.
  • Interacts with the cholesterol medicine Simvastatin.
No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.
  • Interacts with grapefruit and the cholesterol medicine Simvastatin.
Alcohol
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
  • Not a good medication for you if you drink alcohol.
No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.No alcohol related info.
  • Not a good medication for you if you drink alcohol.
  • Don't drink too much alcohol while taking this medicine.
Food
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
No food related info.
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
  • Take with food or at bedtime to avoid side effects.
  • You have to take Carvedilol with food.
  • Take it with food.
No food related info.No food related info.No food related info.No food related info.No food related info.No food related info.No food related info.No food related info.
Kidneys and liver
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
  • There have been reports of liver damage within the first eight weeks of Cardizem (Diltiazem), particularly if you have a history of liver disease. Your doctor may monitor your liver.
No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
  • Might not be a good choice if you have liver disease.
  • Your body uses your liver to break down Norvasc (Amlodipine) and remove it from your blood. If you have liver disease you may not be able to remove Norvasc (Amlodipine) as quickly from your blood as someone with a healthy liver. You should increase the dose of Norvasc (Amlodipine) slowly and watch closely for how it is working in your body. Increasing the dose slowly will lower your chances of having side effects.
  • Reports of liver damage have occurred while on this medication, especially if you have had cirrhosis. Your doctor will monitor your liver on a regular basis. Tell your doctor if you or your caregivers/family notice your skin or the whites of your eyes are becoming yellower, pain in your abdomen, or sudden confusion.
  • Requires routine blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
  • Zestoretic (Lisinopril / Hydrochlorothiazide) can cause severe allergic reactions, including death, to patients who required certain types of kidney dialysis. Talk to your prescriber if you are undergoing dialysis to discuss possible alternative medications.
  • Zestoretic (Lisinopril / Hydrochlorothiazide) can cause kidney damage, especially if you already have a history of kidney disease. Talk to your doctor to discuss possible alternatives if this is a concern.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • You'll need to have blood tests done to check your kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
No kidneys and liver related info.
  • Your doctor may check your liver regularly, as there have been reports of liver damage which can only be seen through blood tests. If you do have a history of liver disease, let your doctor know.
  • Your doctor may monitor your heart to see if changes to its electrical system may occur, especially if you have had liver or kidney disease in the past.
Pain
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
No pain related info.
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
No pain related info.No pain related info.
  • Worsening heart pain or increased risk of heart attack is possible when you first start taking Norvasc (Amlodipine). This can also happen after you increase the dose of Norvasc (Amlodipine). Notify your doctor immediately if you experience any heart pain, radiating jaw pain, crushing chest pain, or persistent racing heartbeat.
No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.
Sleep
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
No sleep related info.No sleep related info.
  • Can cause drowsiness, headache, dizziness, and nausea.
No sleep related info.No sleep related info.No sleep related info.No sleep related info.No sleep related info.No sleep related info.No sleep related info.
  • Can cause drowsiness, headache, dizziness, and dry mouth.
No sleep related info.
Upsides and benefits
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • You can take it alone or with other medicines to help lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Treats certain abnormal heart rhythms.
  • A first-choice treatment to prevent chest pain (angina).
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for people who've had a heart attack.
  • Lopressor (metoprolol tartrate) lowers the risk of death during and after a heart attack.
  • Lopressor (metoprolol tartrate) is cheaper than the extended release version.
  • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
  • Makes urination easier in men with an enlarged prostate.
  • Helps people with PTSD get better sleep with fewer, less-intense nightmares.
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure and heart attack.
  • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Each dose lasts longer than other calcium channel blockers, which keeps blood pressure consistent without big ups and downs.
  • Particularly good at lowering systolic blood pressure (the top number), so it's a good option for older people who can commonly get high blood pressure only in the top number.
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • You can take it alone or with other medicines to help lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Treats certain abnormal heart rhythms.
  • Does a good job getting rid of extra fluids in your body by making you urinate more.
  • A first-choice blood pressure treatment. Works especially well for people of African descent.
  • Lowers the risk of heart attack and stroke.
  • Good option if you have high blood pressure and heart failure.
  • Most people have very few side effects from Microzide (hydrochlorothiazide (HCTZ)).
  • Can be good for patients with osteoporosis since it raises the body's level of calcium.
  • Combination medicine for people with high blood pressure. Doctors might prescribe it when you need more than one medicine to control your blood pressure.
  • The two drugs in Lisinopril/hydrochlorothiazide work together to lower blood pressure, remove extra water from your body, and lower your risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Very cheap drug, and comes available as a liquid for children over 6 years of age.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
  • Available in a weekly patch for people that aren't good at taking medicine by mouth.
  • Works in the brain, so it can help treat some nervous system and psychiatric conditions.
  • Under the brand name Kapvay, it's used to treat ADHD in children and teenagers.
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • You can take it alone or with other medicines to help lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Treats certain abnormal heart rhythms.
Downsides and risks
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Diltiazem than men.
  • You can't miss doses. Stopping Diltiazem suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Some brands of Diltiazem have to be taken with food, so listen carefully for instructions from your doctor or pharmacist.
  • Not a good medication for you if you drink alcohol.
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
  • Taking Lopressor (metoprolol tartrate) may make you feel more tired or out of breath during exercise or your normal daily routines. This gets better for most people, but for some it may not go away.
  • Not a first-choice treatment for high blood pressure, unless you have heart failure or heart disease. It can also be added to other medicines if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Lopressor (metoprolol tartrate) suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Not the best medicine to lower blood pressure by itself.
  • Likely to cause orthostatic hypotension. This means dizziness when you change positions (like standing up) because your blood pressure doesn't adjust quickly enough.
  • Not preferred for people 65 years or older.
  • You have to take Carvedilol with food.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Amlodipine than men.
  • Some people might experience flushing with this medication.
  • You can't miss doses. Stopping Amlodipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • If you have severe heart disease, using Amlodipine might increase your risk of chest pain or heart attack during the time right after starting the medication or raising the dosage.
  • Might not be a good choice if you have liver disease.
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Nifedipine than men.
  • You can't miss doses. Stopping Nifedipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Not a good medication for you if you love grapefruit. It can make Nifedipine have a stronger effect on your blood pressure.
  • Makes you urinate more often.
  • Microzide (hydrochlorothiazide (HCTZ)) doesn't work well in people with severe kidney problems.
  • It can increase the risk of gout attacks in people with poor kidney function or a history of gout.
  • People with a sulfa allergy may be allergic to Microzide (hydrochlorothiazide (HCTZ)).
  • Comes in fixed dosage strengths, so it's harder for your doctor to adjust your dose.
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Makes you urinate more often.
  • Doesn't work as well in people with severe kidney problems.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Zestril (lisinopril) isn't safe to use if you're pregnant.
  • Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Has a lot of side effects compared to other blood pressure-lowering medicine because it works in the brain.
  • The pill form can make some people sleepy, dizzy, and have dry mouth.
  • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Verapamil than men.
  • You can't miss doses. Stopping Verapamil suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Not a good medication for you if you drink alcohol.
Tips from our pharmacists for people taking the medication
DiltiazemLopressorPrazosinCoregNorvascNifedipinehydrochlorothiazideZestoreticLisinoprilDiovanCatapresCalan
  • Can cause dizziness or fatigue in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Interacts with the cholesterol medicine Simvastatin.
  • Can cause ankle or foot swelling.
  • Can cause gum overgrowth. Ask your dentist to check for this side effect.
  • You should take Lopressor (metoprolol tartrate) with or after meals.
  • Lopressor (metoprolol tartrate) can make you feel dizzy for the first few days. It can also cause fatigue and headaches.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly unless your doctor tells you to.
  • This is the immediate release version of the medication, so it needs to be taken twice a day. It's different from the extended release form: Toprol XL (metoprolol succinate).
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause drowsiness, headache, dizziness, and nausea.
  • Take with food or at bedtime to avoid side effects.
  • If side effects don't go away, talk to your doctor about alternatives.
  • Recheck your blood pressure 1 week after starting this medicine.
  • Take it with food.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause fatigue and erectile dysfunction.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Interacts with the cholesterol medicine Simvastatin.
  • Can cause ankle or foot swelling.
  • Can cause gum overgrowth. Ask your dentist to check for this side effect.
  • Can cause dizziness or headaches in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause face flushing and ankle or foot swelling.
  • Avoid grapefruit while taking this medicine.
  • Your doctor might do routine blood tests to check your liver function.
  • Microzide (hydrochlorothiazide (HCTZ)) starts working in about 2 hours.
  • It makes you urinate more often, so don't take it at bedtime.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any tiredness or muscle weakness that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Makes you urinate more often, so avoid taking it at bedtime.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.
  • Can cause dizziness the first few days you're taking it.
  • Check your blood pressure about 1 week after starting Zestril (lisinopril), and tell your doctor if it hasn't improved.
  • Let your doctor know about any dizziness, tiredness, cough, or throat irritation that doesn't go away.
  • You'll need to have blood tests done to check your kidney function.
  • Don't take Zestril (lisinopril) if you're pregnant.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.
  • Usually taken together with other medicines for better blood pressure control.
  • Can cause drowsiness, headache, dizziness, and dry mouth.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • If side effects don't go away, talk to your doctor about alternatives.
  • The weekly patch form can have fewer side effects.
  • Don't stop taking this medicine suddenly.
  • Extended release tablet also used to treat ADHD.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Interacts with grapefruit and the cholesterol medicine Simvastatin.
  • Can cause constipation and headache.
  • Don't drink too much alcohol while taking this medicine.
  • Your doctor might do routine blood tests to check your liver function.
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