Prescription onlyNo lower cost generic available

Zonalon

(Doxepin)

  • Cream, gel, or ointment
  • Skin intching (moderate)
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Helps you stop itching.

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Prescription onlyNo lower cost generic available

Our pharmacists’ bottom line

Zonalon (Doxepin) works well treating itchy skin, but could make you sleepy.

  • In clinical trials, Zonalon (Doxepin) was found to be the most effective cream for treating itchy skin.
  • You can use Zonalon (Doxepin) for up to 8 days at a time.
  • You need a prescription for Zonalon (Doxepin).
  • It isn't available as a generic, so it could be kind of pricey.
  • Zonalon (Doxepin) can make you sleepy.
  • Zonalon (Doxepin) can interact with other medications, vitamins, or alternative treatments.

Save on your next Zonalon (Doxepin) prescription

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Side effects for Zonalon (Doxepin)

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These are side effects of Zonalon (Doxepin) reported to the FDA by people taking it, and by doctors and pharmacists.

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What to expect when you take Zonalon (Doxepin)

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Tips from our pharmacists
  • Be sure the affected area is clean and dry before applying Zonalon (Doxepin).
  • Wash your hands before and after using it.
  • Apply a thin layer of Zonalon (Doxepin) onto the affected area and rub it in gently.
  • Don’t put a bandage, dressing, or make-up over Zonalon (Doxepin) once it's on your skin.
  • It shouldn't affect you too much, but avoid activities that need you to be fully alert (like driving) until you know how it works.

Risks and Warnings for Zonalon (Doxepin)

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  • Using Zonalon (Doxepin) can make you sleepy. This is especially true if you use a lot of it on your body. Be sure to avoid activities that you need to be fully alert like driving, until you know how Zonalon (Doxepin) affects you. Alcohol, antihistamines, and other medications that cause sleepiness can add to the effects of Zonalon (Doxepin).

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Zonalon (Doxepin)

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The FDA category for this medication is B. It is advised that you: Probably safe
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  • Risks from our pharmacists
  • Using Zonalon (Doxepin) can make you sleepy. This is especially true if you use a lot of it on your body. Be sure to avoid activities that you need to be fully alert like driving, until you know how Zonalon (Doxepin) affects you. Alcohol, antihistamines, and other medications that cause sleepiness can add to the effects of Zonalon (Doxepin).