Duavee

(conjugated estrogens / bazedoxifene)

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Relieves hot flashes from menopause and strengthens your bones.

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Our bottom line

Duavee (conjugated estrogens / bazedoxifene) is a once daily pill that helps with symptoms of menopause.

Quick facts about Duavee
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (conjugated estrogens / bazedoxifene)
Prices and discounts
Lowest price for 30 0.45mg-20mg tablets
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$168.78

Upsides

  • In studies, many women started to feel better about a month after starting the medicine.
  • Relieves multiple symptoms from low estrogen, such as hot flashes and vaginal dryness.
  • Can be used by women who have an intact uterus.
  • Unlike most other estrogen medicines used for menopause, Duavee (conjugated estrogens / bazedoxifene) doesn't increase your risk for breast cancer when used by itself.
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Downsides

  • Brand name only, so it is expensive.
  • Compared to other medicines that help with symptoms of menopause, you might be more likely to have blood clots with Duavee (conjugated estrogens / bazedoxifene).
  • Not a good choice for women with liver problems or bleeding problems.
Prices and discounts
Lowest price for 30 0.45mg-20mg tablets
Determining your location...
$168.78
How it works

Duavee (conjugated estrogens / bazedoxifene) is a combination medicine that helps to relieve symptoms of menopause as well as prevent your bones from thinning. The estrogen in the pill replaces the hormone your body loses during menopause. The bazedoxifene helps to boost the effects of the estrogen in some parts of the body and stops it in others to help protect the uterus.

Quick facts about Duavee
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (conjugated estrogens / bazedoxifene)

Used for

Dosage forms

  • Pill
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What to expect when you take Duavee (conjugated estrogens / bazedoxifene) for Osteoporosis prevention

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Side effect rates for Duavee (conjugated estrogens / bazedoxifene)

2293 
From clinical trials of Duavee / All (0.45mg/20mg)
  • Muscle spasms
  • Nausea
  • Diarrhea
  • Indigestion
  • Upper stomach pain
  • Mouth and throat pain
  • Neck pain
  • Dizziness

Risks and Warnings for Duavee (conjugated estrogens / bazedoxifene)

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    • Higher risk if:
    • Using estrogen for more than one year

    Using medicines like Duavee (conjugated estrogens / bazedoxifene) for more than a year can increase your risk of uterus (endometrial) cancer. Let your doctor know if you notice any unusual bleeding. Talk to your doctor about other medicines you can take with Duavee (conjugated estrogens / bazedoxifene) to protect yourself from cancer if you are worried.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Duavee (conjugated estrogens / bazedoxifene)

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Price
  • I wish I had known there were so pricey before I started taking them. My Dr. Gave me samples for like the 2 first months and then when I had to order it almost die. But I was feeling miserable so I paid $100 copay for 2 more months but couldn't after that so back to misery :(
Kidneys and liver
  • Duavee (conjugated estrogens / bazedoxifene) can't be taken by women who have liver problems. Tell your doctor before you are given Duavee (conjugated estrogens / bazedoxifene) if you have ever had problems with your liver. Your doctor will need to choose a different medicine for you.
  • Not a good choice for women with liver problems or bleeding problems.
Pain
  • Duavee (conjugated estrogens / bazedoxifene) can increase your risk of blood clots, which can be very dangerous. You're more likely to have them if you smoke tobacco, are obese, or if you or your family have ever had blood clots. Get medical care right away if you have pain in your legs or arms, bad headaches, trouble breathing, or sudden changes in your speech or vision.