Prescription onlyClass: Cardiovascular

DutoprolAlternatives

(metoprolol succinate / hydrochlorothiazide)

Prescription onlyClass: Cardiovascular
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Compare Dutoprol (metoprolol succinate / hydrochlorothiazide) to alternatives

These medications are comparable to Dutoprol (metoprolol succinate / hydrochlorothiazide) or used for similar purposes.

Dutoprol
(metoprolol succinate / hydrochlorothiazide)

Lopressor
(metoprolol tartrate)

Microzide
(hydrochlorothiazide )

Tenoretic
(atenolol / chlorthalidone)

Ziac
(bisoprolol / hydrochlorothiazide)

Lotensin
(benazepril)

Hyzaar
(losartan / hydrochlorothiazide)

Lowers blood pressure. Dutoprol (Metoprolol Succinate / Hydrochlorothiazide) helps lower blood pressure by working in two different ways in your body. It's good for stubbornly high blood pressure.Lowers blood pressure and controls heart rate. Lopressor (metoprolol tartrate) lowers high blood pressure, controls chest pain, and helps treat heart failure and heart attack. You need to take it with food and can't miss a dose.Removes water from the body, which lowers blood pressure. Microzide (hydrochlorothiazide (HCTZ)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Coming soon.Coming soon.Lowers blood pressure. Lotensin (benazepril) is a good blood pressure-lowering medicine that also protects kidney function.Lowers blood pressure. Removes extra water from your body. Hyzaar (Losartan / Hydrochlorothiazide) is a good combination blood pressure-lowering medicine to try if your blood pressure is very high.
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Reviews & ratings
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Not enough reviews for this drug. Help someone out, leave a review!

Have you used Dutoprol (metoprolol succinate / hydrochlorothiazide)?
Worth itNot sureNot worth it
Reviews for Lopressor (metoprolol tartrate)
62%
-38% worse vs. Dutoprol (metoprolol succinate / hydrochlorothiazide)
47%
-10% worse vs. Dutoprol (metoprolol succinate / hydrochlorothiazide)
15%
-15% worse vs. Dutoprol (metoprolol succinate / hydrochlorothiazide)
464 reviews
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
Reviews for Microzide (hydrochlorothiazide )
47%
-53% worse vs. Dutoprol (metoprolol succinate / hydrochlorothiazide)
31%
-26% worse vs. Dutoprol (metoprolol succinate / hydrochlorothiazide)
16%
-16% worse vs. Dutoprol (metoprolol succinate / hydrochlorothiazide)
139 reviews
Have you used Microzide (hydrochlorothiazide )?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Tenoretic (atenolol / chlorthalidone)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Ziac (bisoprolol / hydrochlorothiazide)?
Worth itNot sureNot worth it
Reviews for Lotensin (benazepril)
61%
-39% worse vs. Dutoprol (metoprolol succinate / hydrochlorothiazide)
64%
+7% better vs. Dutoprol (metoprolol succinate / hydrochlorothiazide)
23%
-23% worse vs. Dutoprol (metoprolol succinate / hydrochlorothiazide)
Have you used Lotensin (benazepril)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Hyzaar (losartan / hydrochlorothiazide)?
Worth itNot sureNot worth it
Side effects
DutoprolLopressorhydrochlorothiazideTenoreticZiacbenazeprilHyzaar
  • Common cold 2%
  • Fatigue 2%
  • Back pain 1%
More Dutoprol side effects »
  • Tiredness 10%
  • Dizziness 10%
  • Low mood disorder 5%
  • Diarrhea 5%
  • Itching or skin rash 5%
  • Shortness of breath 3%
  • Slowed heart rate 3%
  • Low blood pressure 4%
More Lopressor side effects »

The hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about hydrochlorothiazide side effects »

We haven’t found good data for Tenoretic side effects.

FDA side effect reports for Tenoretic »

We haven’t found good data for Ziac side effects.

FDA side effect reports for Ziac »
  • Headache 2%
  • Dizziness 2%
  • Drowsiness 2%
  • Dizziness when standing up 2%
More benazepril side effects »
  • Dizziness 3%
  • Upper respiratory infection 1%
  • Cough 1%
  • Back pain 1%
More Hyzaar side effects »
How it works
DutoprolLopressorhydrochlorothiazideTenoreticZiacbenazeprilHyzaar
Dutoprol (Metoprolol Succinate / Hydrochlorothiazide) is a combination medicine that helps control your blood pressure and reduce the risk of a heart attack or stroke. Hydrochlorothiazide is a diuretic that removes extra water from your body. Metoprolol is a beta blocker that lowers your heart rate.Lopressor (metoprolol tartrate) is a beta blocker. It lowers blood pressure by slowing your heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Microzide (hydrochlorothiazide (HCTZ)) is a thiazide diuretic (water pill) that makes you urinate more. It works in the kidneys to remove extra water and certain electrolytes, while lowering blood pressure and reducing swelling.Coming soon.Coming soon.Lotensin (benazepril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Hyzaar (Losartan / Hydrochlorothiazide) is a combination medicine that lowers your blood pressure. Hydrochlorothiazide is a diuretic that removes extra water from your body. Losartan is an angiotensin receptor blocker (ARB) that relaxes your blood vessels to lower you blood pressure and allow more blood and oxygen to get to your heart and other organs.
Type of medication
DutoprolLopressorhydrochlorothiazideTenoreticZiacbenazeprilHyzaar
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Available as
DutoprolLopressorhydrochlorothiazideTenoreticZiacbenazeprilHyzaar
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
Used for
DutoprolLopressorhydrochlorothiazideTenoreticZiacbenazeprilHyzaar
  • Hypertension
  • Hypertension
Risk factors for serious side effects
DutoprolLopressorhydrochlorothiazideTenoreticZiacbenazeprilHyzaar
  • Sudden discontinuation of medicine
  • History of asthma
  • History of diabetes
  • Age 65 years or older
  • Using other medicine(s) that slows the heart
  • Current electrolyte imbalance
  • History of gout
  • Current kidney problems
Detailed Dutoprol (metoprolol succinate / hydrochlorothiazide) risks & warnings »
  • Suddenly stopping Lopressor (metoprolol tartrate)
  • Coronary artery disease
  • Diabetes
    • Heart failure
    • Major surgery requiring anesthesia
    • Asthma
    • COPD
    Detailed Lopressor (metoprolol tartrate) risks & warnings »
    • Current electrolyte imbalance
    • Lower kidney function
    • Dehydration
    • History of sulfa allergies
    • History of gout
    • Current kidney problems
    • History of sulfa or penicillin allergies
    • Diabetes
    Detailed Microzide (hydrochlorothiazide ) risks & warnings »
    Coming soon.Coming soon.
    • Women of childbearing age
    • Infants less than one year old
    • African descent
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
      • Current kidney problems
      • Taking other medicines that increase potassium
      • Using salt substitutes
      • Kidney disease
      Detailed Lotensin (benazepril) risks & warnings »
      • Women of childbearing age
      • History of kidney problems
      • African descent
      • Current kidney problems
      • Medicine that affects potassium
      • Use of salt substitute
      • History of sulfa allergies
      • History of gout
      • Current kidney problems
      Detailed Hyzaar (losartan / hydrochlorothiazide) risks & warnings »
      Pregnancy

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Interactions
      DutoprolLopressorhydrochlorothiazideTenoreticZiacbenazeprilHyzaar
      No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.
      • This drug interacts with other medications that affect potassium, so it needs to be dosed carefully.
      No interactions related info.
      Food
      DutoprolLopressorhydrochlorothiazideTenoreticZiacbenazeprilHyzaar
      No food related info.
      • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
      No food related info.No food related info.No food related info.No food related info.No food related info.
      Kidneys and liver
      DutoprolLopressorhydrochlorothiazideTenoreticZiacbenazeprilHyzaar
      • Check your blood pressure and kidney function 1 week after starting the medicine, then routinely after that.
      No kidneys and liver related info.
      • Requires routine blood tests to check kidney function.
      No kidneys and liver related info.No kidneys and liver related info.
      • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
      • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
      • Requires a yearly blood test to see how the medicine is affecting your electrolytes and kidneys.
      • Needs dose adjustment if you have liver problems.
      • Get your blood pressure, potassium, and kidney function checked 1 week after starting the medicine, then routinely after.
      • Requires routine blood tests to check kidney function.
      • Hyzaar (Losartan / Hydrochlorothiazide) can affect the potassium level in your body. Too much potassium can cause heart problems and too little potassium can cause muscle problems. Baseline and routine lab tests are needed to measure your potassium and kidney function.
      Pain
      DutoprolLopressorhydrochlorothiazideTenoreticZiacbenazeprilHyzaar
      No pain related info.
      • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
      No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.
      Upsides and benefits
      DutoprolLopressorhydrochlorothiazideTenoreticZiacbenazeprilHyzaar
      • Lowers the risk of heart attack and stroke.
      • Combines the benefits of two blood pressure-lowering medicines in a single pill.
      • Helpful in getting rid of extra fluids in your body.
      • A first-choice treatment to prevent chest pain (angina).
      • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
      • A first-choice treatment for people who've had a heart attack.
      • Lopressor (metoprolol tartrate) lowers the risk of death during and after a heart attack.
      • Lopressor (metoprolol tartrate) is cheaper than the extended release version.
      • Does a good job getting rid of extra fluids in your body by making you urinate more.
      • A first-choice blood pressure treatment. Works especially well for people of African descent.
      • Lowers the risk of heart attack and stroke.
      • Good option if you have high blood pressure and heart failure.
      • Most people have very few side effects from Microzide (hydrochlorothiazide (HCTZ)).
      • Can be good for patients with osteoporosis since it raises the body's level of calcium.
      Coming soonComing soon
      • A first-choice blood pressure treatment for many people.
      • Lowers the risk of heart attack and stroke.
      • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
      • Lowers the risk of heart attack and stroke.
      • A first-choice treatment for severe high blood pressure, combining the benefits of two blood pressure-lowering medicines with a single pill.
      • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
      • Helpful in getting rid of extra fluids if you have issues with fluid balance (like in congestive heart failure).
      • Most people have few side effects.
      Downsides and risks
      DutoprolLopressorhydrochlorothiazideTenoreticZiacbenazeprilHyzaar
      • Not the first choice to lower blood pressure.
      • Brand only, can be more expensive.
      • Can make you urinate more often and feel out of breath during physical activities, which may not go away.
      • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
      • Forgetting to take the medicine or stopping it suddenly can cause a heart attack.
      • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
      • Taking Lopressor (metoprolol tartrate) may make you feel more tired or out of breath during exercise or your normal daily routines. This gets better for most people, but for some it may not go away.
      • Not a first-choice treatment for high blood pressure, unless you have heart failure or heart disease. It can also be added to other medicines if your blood pressure is still too high.
      • Can hide symptoms of low blood sugar if you're diabetic.
      • You can't miss doses. Stopping Lopressor (metoprolol tartrate) suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
      • Makes you urinate more often.
      • Microzide (hydrochlorothiazide (HCTZ)) doesn't work well in people with severe kidney problems.
      • It can increase the risk of gout attacks in people with poor kidney function or a history of gout.
      • People with a sulfa allergy may be allergic to Microzide (hydrochlorothiazide (HCTZ)).
      Coming soonComing soon
      • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
      • Requires a regular blood test to see how the medicine is affecting your body.
      • Not safe to use if you're pregnant.
      • This drug interacts with other medications that affect potassium, so it needs to be dosed carefully.
      • Will make you urinate more often.
      • Requires a yearly blood test to see how the medicine is affecting your electrolytes and kidneys.
      • Not safe to use if you're pregnant.
      • Needs dose adjustment if you have liver problems.
      • Your skin will be more sensitive to the sun while taking this.
      • Won't work as well if you have severe kidney problems.
      • Shouldn't take if you have a sulfa allergy.
      Tips from our pharmacists for people taking the medication
      DutoprolLopressorhydrochlorothiazideTenoreticZiacbenazeprilHyzaar
      • Makes you urinate more often, so don't take it too close to bedtime.
      • Can make you feel dizzy or short of breath the first few days, but this should improve as your body gets used to the medicine.
      • Check your blood pressure and kidney function 1 week after starting the medicine, then routinely after that.
      • Tell your doctor about any cold-like symptoms, dizziness, headache, fatigue, or muscle weakness that doesn't go away.
      • Don't stop taking this medicine suddenly since it can trigger heart problems.
      • You should take Lopressor (metoprolol tartrate) with or after meals.
      • Lopressor (metoprolol tartrate) can make you feel dizzy for the first few days. It can also cause fatigue and headaches.
      • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
      • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
      • Don't stop taking this medicine suddenly unless your doctor tells you to.
      • This is the immediate release version of the medication, so it needs to be taken twice a day. It's different from the extended release form: Toprol XL (metoprolol succinate).
      • Microzide (hydrochlorothiazide (HCTZ)) starts working in about 2 hours.
      • It makes you urinate more often, so don't take it at bedtime.
      • Can cause dizziness in the first few days.
      • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
      • Tell your doctor about any tiredness or muscle weakness that doesn't go away.
      • Requires routine blood tests to check kidney function.
      Coming soonComing soon
      • Can cause dizziness in the first few days.
      • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it doesn't get better.
      • Tell your doctor about any tiredness, cough, mouth swelling, or throat irritation that doesn't go away.
      • Requires blood tests to check potassium levels and kidney function.
      • Don't take it if you're pregnant.
      • Can cause dizziness in the first few days.
      • Get your blood pressure, potassium, and kidney function checked 1 week after starting the medicine, then routinely after.
      • Tell your doctor about any dizziness or muscle weakness that doesn't go away.
      • Get immediate medical help if you notice any swelling, especially around your head and neck.
      • Requires routine blood tests to check kidney function.
      • Don't take it if you're pregnant.
      Learn more
      More about DutoprolSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Dutoprol (metoprolol succinate / hydrochlorothiazide)?
      Worth itNot sureNot worth it
      More about LopressorSide effectsReviews & ratingsFDA package insert
      Have you used Lopressor (metoprolol tartrate)?
      Worth itNot sureNot worth it
      More about hydrochlorothiazideSide effectsReviews & ratingsFDA package insert
      Have you used Microzide (hydrochlorothiazide )?
      Worth itNot sureNot worth it
      More about TenoreticSide effectsReviews & ratingsFDA package insert
      Have you used Tenoretic (atenolol / chlorthalidone)?
      Worth itNot sureNot worth it
      More about ZiacSide effectsReviews & ratingsFDA package insert
      Have you used Ziac (bisoprolol / hydrochlorothiazide)?
      Worth itNot sureNot worth it
      More about benazeprilSide effectsReviews & ratingsFDA package insert
      Have you used Lotensin (benazepril)?
      Worth itNot sureNot worth it
      More about HyzaarSide effectsReviews & ratingsFDA package insert
      Have you used Hyzaar (losartan / hydrochlorothiazide)?
      Worth itNot sureNot worth it