Effexor

(venlafaxine)

3.7/ 5 average rating with 577 reviewsforEffexor
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Improves mood and helps you relax.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Effexor (venlafaxine) is good for treating depression and anxiety, but it can cause more withdrawal symptoms if you stop suddenly compared to other antidepressants.

Quick facts about Effexor
  • Drug class: Mental health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (venlafaxine)
Prices and discounts
Lowest price for 60 75mg tablets
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$16.20

Upsides

  • Effexor (venlafaxine) effectively treats depression, anxiety, and panic disorder.
  • Effexor (venlafaxine) causes more sleepiness than other antidepressants, so it's beneficial for people who have trouble sleeping.
  • Effexor (venlafaxine) might work when other antidepressants haven't worked since it affects two chemicals in the brain that impact your mood.
  • Effexor (venlafaxine) has several uses, which may be good for people with multiple conditions.
  • Effexor (venlafaxine) is available in generic, which is cheaper.

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What to expect from Effexor, on one page

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People’s experience with Effexor

577reviews so far. What do you think?

Downsides

  • Effexor (venlafaxine) can cause side effects such as decreased libido and increased blood pressure.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people aged 24 years or younger.
  • Compared to other antidepressants, it's more likely to cause unpleasant withdrawal symptoms if you suddenly stop taking it and can causes more sleepiness.

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Get our free fact sheet

What to expect from Effexor, on one page

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Prices and discounts
Lowest price for 60 75mg tablets
Determining your location...
$16.20
How it works

Effexor (venlafaxine) is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. It increases serotonin and norepinephrine activity in the brain, which help regulate mood.

Quick facts about Effexor
  • Drug class: Mental health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (venlafaxine)

Used for

Dosage forms

  • Pill
  • Extended release
People’s experience with Effexor

577reviews so far. What do you think?

What to expect when you take Effexor (venlafaxine) for Panic disorder

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Skip side effects section. Skip to risks and warnings section.

Side effect rates for Effexor (venlafaxine)

From 1642 clinical trials of Effexor when taken for any indication
  • Nausea
  • Headache
  • Drowsiness
  • Dry mouth
  • Dizziness
  • Difficulty sleeping
  • Constipation
  • Nervousness
  • Weakness
  • Sweating

Risks and Warnings for Effexor (venlafaxine)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • Age 24 years or younger

    Effexor (venlafaxine) may increase the risk of suicidal thoughts or behavior. Watch for worsening depression or any unusual changes in mood or behavior, especially during the first few months of treatment or with dose changes. Report anything concerning to a doctor immediately. Effexor (venlafaxine) is not approved for use in children younger than age 18.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Effexor (venlafaxine)

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Alcohol
  • Reviewed Effexoron 5/15/2017Do not use alcohol while taking this drug - I had 3 drinks one evening while on this, which normally would make me tipsy, but fine. I nearly ended up in the E.R. because I vomited so much (about 30 times in 2 hours), and I ended up feeling horribly depressed and in terrible stomach and head pain. Also made my anxiety significantly worse.
    22
    Woman
    A month or so
    Depression
  • Reviewed Effexoron 6/11/2017Venlafaxine and a generous amount of alcohol (as in a night of partying) may cause a state of hypomania with very impolitic behaviour.
    25
    Man
    Two years or more
    Social anxiety
Food
  • Reviewed Effexoron 6/23/2016Take it in the morning after breakfast is the best way. If you don't want to eat with it, still take it in the morning. It helps with energy for me.
    33
    Woman
    Depression
  • Reviewed Effexoron 8/18/2016Take this with food as prescribed or you feel awful.
    38
    Woman
    Anxiety
  • Reviewed Effexoron 10/14/2016Try never forget a dose, and take with a meal. I'm unluckily much hungrier since I take it, and eat much more carbs than before. More nervous energy, less physical energy.
    56
    Woman
    Depression
Sex
  • Reviewed Effexoron 10/26/2016Orgasm and ejaculation can be very difficult. Do NOT miss a dose. I thought I was dying.
    49
    Man
    Depression
  • Reviewed Effexoron 1/19/2017Switched from prozac to effexor to avoid low libido. It did not make a difference in this area at all, if not it made the problem worse. Weight gain of 20 lbs in 1 year and we months of treatment. Also caused horrible constipation. Would never take again!
    34
    Woman
    Depression
  • Reviewed Effexoron 9/26/2017No libido after 1 tablet
    59
    Man
    Less than a week
    Depression
Sleep
  • Effexor (venlafaxine) may cause dizziness or drowsiness. Do not drive or operate heavy machinery until you know how this medicine affects you.
  • Reviewed EffexorTake it night. Sleep like a baby.
    39
    Man
  • Reviewed Effexoron 9/24/2016Made me very sleepy. Felt nauseous if I didn't take daily dose at the same time every day. I also noticed that I felt really hot all the time and sweaty. Worked fairly well for addressing depression concerns but was not worth the drowsiness
    33
    Woman
    Depression
  • Reviewed Effexoron 10/16/2016Very drowsy on it. Low sex drive... still worked better than Zoloft.
    34
    Woman
    Depression
Weight
  • Reviewed Effexorweight gain is an issue
    65
    Woman
    Two years or more
    Depression
  • Reviewed Effexoron 8/9/2016Been on XR version for a bit over a month. I take it in the AM because it gives me energy. Helps me focus and I feel a lot better. Have lost a little weight too!
    22
    Man
    Depression
  • Reviewed Effexoron 2/20/2017This mediction caused huge weight gain for me and the withdrawal symptoms are awful. The body shocks as you are coming off this medication are terrible!
    46
    Woman
    Depression

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