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Elavil Alternatives

(Amitriptyline)

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Compare Elavil (Amitriptyline) to alternatives

These medications are comparable to Elavil (Amitriptyline) or used for similar purposes.

Elavil
(Amitriptyline)

Cymbalta
(Duloxetine)

Norpramin
(Desipramine)

Celexa
(Citalopram)

Neurontin
(Gabapentin)

Zoloft
(Sertraline)

Remeron
(Mirtazapine)

Pamelor
(Nortriptyline)

Oleptro
(Trazodone)

Paxil
(Paroxetine)

Tofranil
(Imipramine Hydrochloride)

Effexor
(Venlafaxine)

Improves mood and relieves certain kinds of pain. Elavil (Amitriptyline) is an older antidepressant that's sometimes used to treat pain and sleep problems, but it can have more side effects than similar medications.Improves mood and relieves certain kinds of pain. Cymbalta (Duloxetine) is good for treating depression and anxiety, and may help with chronic pain. More likely than other antidepressants to cause problems if you drink or have high blood pressure.Coming soon.Improves mood and helps you relax. Celexa (Citalopram) is good for treating depression and anxiety. Might be less likely to cause side effects than some antidepressants, but not the best choice for people with heart or liver problems.Treats tingling and burning nerve pain. Neurontin (Gabapentin) is an old seizure disorder medicine that's now used to treat nerve-related pain caused by different conditions.Improves mood and helps you relax. Zoloft (Sertraline) is good for treating depression and anxiety. It's more likely to cause insomnia and diarrhea than other antidepressants.Improves mood. Remeron (Mirtazapine) is okay for treating depression and good for sleep. More likely to cause weight gain than any other antidepressant.Improves your mood. Pamelor (Nortriptyline) is a good option for treating depression, especially for people who also have problems with persistent nerve pain.Improves mood and helps you sleep. Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.Improves mood and helps you relax. Paxil (Paroxetine) is good for treating depression and anxiety but it causes more weight gain, sleepiness, and withdrawal symptoms than other antidepressants.Coming soon.Improves mood and helps you relax. Effexor (Venlafaxine) is good for treating depression and anxiety. May work when other antidepressants haven't, it's but more likely to cause side effects and withdrawal symptoms than other antidepressants.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.466101694915254Elavil
Reviews for Elavil (Amitriptyline)
52%
of people say Elavil (Amitriptyline) is worth it
34%
say it works well
23%
say it's a big hassle
Reviews for Cymbalta (Duloxetine)
59%
+7% vs. Elavil (Amitriptyline)
49%
+15% vs. Elavil (Amitriptyline)
24%
1% vs. Elavil (Amitriptyline)

Not enough reviews for this drug. Help someone out, leave a review!

Reviews for Celexa (Citalopram)
60%
+8% vs. Elavil (Amitriptyline)
50%
+16% vs. Elavil (Amitriptyline)
15%
+8% vs. Elavil (Amitriptyline)
Reviews for Neurontin (Gabapentin)
57%
+5% vs. Elavil (Amitriptyline)
39%
+5% vs. Elavil (Amitriptyline)
19%
+4% vs. Elavil (Amitriptyline)
Reviews for Zoloft (Sertraline)
59%
+7% vs. Elavil (Amitriptyline)
40%
+6% vs. Elavil (Amitriptyline)
15%
+8% vs. Elavil (Amitriptyline)
Reviews for Remeron (Mirtazapine)
47%
5% vs. Elavil (Amitriptyline)
42%
+8% vs. Elavil (Amitriptyline)
26%
3% vs. Elavil (Amitriptyline)

Not enough reviews for this drug. Help someone out, leave a review!

Reviews for Oleptro (Trazodone)
72%
+20% vs. Elavil (Amitriptyline)
48%
+14% vs. Elavil (Amitriptyline)
24%
1% vs. Elavil (Amitriptyline)
Reviews for Paxil (Paroxetine)
52%
Same vs. Elavil (Amitriptyline)
39%
+5% vs. Elavil (Amitriptyline)
23%
Same vs. Elavil (Amitriptyline)

Not enough reviews for this drug. Help someone out, leave a review!

Reviews for Effexor (Venlafaxine)
61%
+9% vs. Elavil (Amitriptyline)
50%
+16% vs. Elavil (Amitriptyline)
22%
+1% vs. Elavil (Amitriptyline)
Side effects
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor

The Elavil FDA package insert doesn’t have numbers about how common side effects are.

More about Elavil side effects »
  • Nausea 15%
  • Dry mouth 8%
  • Drowsiness 8%
  • Constipation 7%
  • Somnolencee 7%
  • Decreased appetite 7%
  • Fatigued 6%
  • Sleep difficulty 5%
  • Dizziness 4%
  • Fatigue 4%
More Cymbalta side effects »

We haven’t found good data for Norpramin side effects.

FDA side effect reports for Norpramin »
  • Drowsiness 8%
  • Nausea 7%
  • Dry mouth 6%
  • Abnormal ejaculation 5%
  • Ejaculation disorder 5%
  • Diarrhea 3%
  • Tremor 2%
  • Sweating increased 2%
  • Fatigue 2%
  • Loss of appetite 2%
More Celexa side effects »
  • Dizziness 21%
  • Drowsiness 16%
  • Lack of muscle coordination 7%
  • Leg or ankle swelling 6%
  • Fatigue 6%
  • Hostility 5%
  • Involuntary eye movement 4%
  • Double vision 4%
  • Tremor 4%
  • Dry mouth 4%
More Neurontin side effects »
  • Nausea 19%
  • Ejaculation failure 18%
  • Sleep difficulty 16%
  • Diarrhea/loose stools 14%
  • Fatigue 9%
  • Loss of appetite 9%
  • Lower sex drive 9%
  • Sweating increased 9%
  • Dizziness 8%
  • Indigestion 8%
More Zoloft side effects »
  • Drowsiness 36%
  • Increased appetite 15%
  • Dry mouth 10%
  • Weight gain 10%
  • Constipation 6%
  • Dizziness 4%
  • Muscle weakness 3%
  • Abnormal dreams 3%
  • Flu syndrome 2%
  • Thinking abnormal 2%
More Remeron side effects »

We haven’t found good data for Pamelor side effects.

FDA side effect reports for Pamelor »
  • Somnolence/sedation 27%
  • Drowsiness 21%
  • Dry mouth 14%
  • Dizziness/lightheadedness 13%
  • Dizziness 13%
  • Blurred vision 11%
  • Nausea 8%
  • Fatigue 7%
  • Skin condition/edema 6%
  • Headache 6%
More Oleptro side effects »
  • Abnormal ejaculation† 27%
  • Ejaculatory disturbance 26%
  • Nausea 22%
  • Dry mouth 19%
  • Drowsiness 17%
  • Lower sex drive 11%
  • Diarrhea 11%
  • Sleep difficulty 11%
  • Constipation 10%
  • Decreased libido 10%
More Paxil side effects »

We haven’t found good data for Tofranil side effects.

FDA side effect reports for Tofranil »
  • Nausea 42%
  • Drowsiness 22%
  • Dizziness 20%
  • Nervousness 17%
  • Sleep difficulty 16%
  • Loss of appetite 15%
  • Sweating 14%
  • Dry mouth 13%
  • Dry mouth 11%
  • Muscle weakness 10%
More Effexor side effects »
How it works
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
Elavil (Amitriptyline) is a tricyclic antidepressant (TCA). Researchers don't know exactly how it works. It may change serotonin and norepinephrine activity in the brain, which regulates mood and pain perception. It also has sedative effects.Cymbalta (Duloxetine) is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. It increases serotonin and norepinephrine activity in the brain, which regulates mood.Coming soon.Celexa (Citalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Neurontin (Gabapentin) is an antiepileptic and nerve pain reliever. Researchers don't know exactly how it works, but it has a similar structure to GABA, a neurotransmitter that calms nerves in the brain and spinal cord.Zoloft (Sertraline) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases the activity of serotonin in the brain, which regulates mood.Remeron (Mirtazapine) is an atypical antidepressant. It stimulates your body to make certain chemicals in the brain, such as serotonin and norepinephrine, which regulate mood.Pamelor (Nortriptyline) is a tricyclic antidepressant (TCA). It helps improve your mood by altering the levels of serotonin, norepinephrine, and other similar chemicals in your brain.Oleptro (Trazodone) is a serotonin reuptake inhibitor (SRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Paxil (Paroxetine) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Coming soon.Effexor (Venlafaxine) is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. It increases serotonin and norepinephrine activity in the brain, which regulate mood.
Type of medication
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
Antidepressant
Tricyclic antidepressant (TCA)
Prescription only
Antidepressant
Serotonin-norepinephrine reuptake inhibitor (SNRI)
Prescription only
Coming soon.
Antidepressant
Selective serotonin reuptake inhibitor (SSRI)
Prescription only
Anticonvulsant
GABA analog
Prescription only
Antidepressant
Selective serotonin reuptake inhibitor (SSRI)
Prescription only
Antidepressant
Noradrenergic and specific serotonergic antidepressant
Prescription only
Antidepressant
Tricyclic antidepressant (TCA)
Prescription only
Antidepressant
Serotonin antagonist and reuptake inhibitor
Prescription only
Antidepressant
Selective serotonin reuptake inhibitor (SSRI)
Prescription only
Coming soon.
Antidepressant
Serotonin-norepinephrine reuptake inhibitor (SNRI)
Prescription only
Available as
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
  • Pill
  • Extended release
  • Pill
  • Pill
  • Oral solution
  • Pill
  • Oral solution
  • Pill
  • Liquid
  • Pill
  • Dissolving tablet
  • Pill
  • Liquid
  • Pill
  • Extended release
  • Pill
  • Extended release tablet
  • Liquid
  • Pill
  • Pill
  • Extended release
Used for (click to learn more)
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
  • Depression
  • Depression Nocturnal enuresis
How well it works for depression
The free Iodine Start program helps people track how well they are improving, and find the right antidepressant faster.
The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Elavil (Amitriptyline)

After 4 weeks using Start and Cymbalta (Duloxetine), here’s how much better people feel.

The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Norpramin (Desipramine)

After 4 weeks using Start and Celexa (Citalopram), here’s how much better people feel.

The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Neurontin (Gabapentin)

After 4 weeks using Start and Zoloft (Sertraline), here’s how much better people feel.

After 4 weeks using Start and Remeron (Mirtazapine), here’s how much better people feel.

The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Pamelor (Nortriptyline)The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Oleptro (Trazodone)

After 4 weeks using Start and Paxil (Paroxetine), here’s how much better people feel.

The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Tofranil (Imipramine Hydrochloride)

After 4 weeks using Start and Effexor (Venlafaxine), here’s how much better people feel.

Risk factors for serious side effects
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
  • Age 24 years or younger
  • History of bipolar disorder
  • At risk for bipolar disorder
  • History of cardiovascular disease
  • Age 65 years or older
  • Age 65 years or older
Detailed Elavil (Amitriptyline) risks & warnings »
Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.Coming soon.
Pregnancy category
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
DFDA pregnancy category (Weigh risks vs. benefits)

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.
  • You can't skip or miss doses since suddenly stopping Neurontin (Gabapentin) can cause seizures. This is even more likely if you drink alcohol, so it might not be the best medication for heavy drinkers.
No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.
  • Take with food to avoid upset stomach.
No specific food-related info.
  • Take with food to avoid upset stomach.
  • Take the extended-release tablet with food.
No specific food-related info.No specific food-related info.
  • Take it with food and/or at bedtime to decrease the potential side effects.
No specific food-related info.
  • Take with food to avoid upset stomach.
No specific food-related info.
  • You can take the extended-release form once a day with food either in the morning or in the evening at about the same time each day.
Kidneys and liver
No specific kidneys and liver-related info.
  • Not a good option if you're a heavy drinker, or if you have liver or kidney problems.
No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.No specific sex-related info.
  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
No specific sex-related info.
  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
No specific sex-related info.No specific sex-related info.
  • Fewer sexual side effects than many other antidepressants.
  • Seek medical attention for unwanted, persistent erection.
  • Can cause more sexual side effects like low libido and an inability to orgasm or ejaculate than most antidepressants.
No specific sex-related info.
  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
Sleep
  • Low doses of Elavil (Amitriptyline) start working in 45 minutes to help you sleep better.
  • Can cause dizziness, drowsiness, constipation, and weight gain.
No specific sleep-related info.No specific sleep-related info.No specific sleep-related info.
  • Neurontin (Gabapentin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, or confusion.
  • Causes less drowsiness than other antidepressants.
No specific sleep-related info.No specific sleep-related info.
  • Commonly used in lower doses to help treat sleep problems (insomnia).
  • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
  • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
  • Comes as a generic medication and is cheaper than many other sleep aides.
  • It causes drowsiness, so it's good for people who have trouble sleeping.
No specific sleep-related info.
  • Causes more sleepiness than other antidepressants, so it's good for people who have trouble sleeping.
Weight
  • It's more likely to cause sleepiness, nausea, constipation, diarrhea, and weight gain (1 to 5 pounds) than other antidepressants.
  • Can cause dizziness, drowsiness, constipation, and weight gain.
No specific weight-related info.No specific weight-related info.
  • Can cause minor weight gain (1 to 5 pounds).
No specific weight-related info.No specific weight-related info.
  • More likely to cause minor weight gain (1 to 5 pounds) and raise cholesterol than any other antidepressant.
  • Good option for people who are underweight or frail, because it can help you gain weight.
  • Can increase appetite and weight.
No specific weight-related info.No specific weight-related info.
  • More likely to cause minor weight gain (1 to 5 pounds) or make you feel sick if you miss a dose than other antidepressants.
  • Can cause weight gain, which can be helpful if you've recently lost weight or have a low appetite.
No specific weight-related info.No specific weight-related info.
Upsides and benefits
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
  • Low doses work well to treat certain kinds of chronic pain. It can take 2 weeks to feel the full effects of the medication.
  • Low doses of Elavil (Amitriptyline) start working in 45 minutes to help you sleep better.
  • Six out of every ten people who use an antidepressant for the first time find that it works for them.
  • Lowers relapse rates for depression.
  • Can relieve some types of chronic pain. Might be particularly good at pain relief for people who are also depressed.
  • Effective at relieving depression and anxiety symptoms.
Coming soon.
  • Causes less sleepiness compared to other antidepressants.
  • Effective at relieving depression and anxiety symptoms.
  • Originally used to treat epilepsy (partial seizures), but now it primarily treats neuropathic pain that's caused by nerve stimulation or damage.
  • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
  • It's available as a generic, so it's less expensive than similar medications.
  • Effective at lowering symptoms and relapse rates of depression and anxiety disorders.
  • Causes less drowsiness than other antidepressants.
  • Effective at relieving some depression symptoms.
  • Starts to work more quickly than most antidepressants.
  • Might be a good option for people who have insomnia with their depression, because it can make you very sleepy.
  • Good option for people who are underweight or frail, because it can help you gain weight.
  • Helpful with treating certain types of pain, like migraines or nerve-related pain.
  • Generally well tolerated and has fewer side effects than other medicines in the same class of drugs.
  • Commonly used in lower doses to help treat sleep problems (insomnia).
  • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
  • Fewer sexual side effects than many other antidepressants.
  • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
  • Comes as a generic medication and is cheaper than many other sleep aides.
  • Lowers relapse rates of depression and anxiety disorders, including OCD, panic disorder, social anxiety disorder, and generalized anxiety disorder.
  • It causes drowsiness, so it's good for people who have trouble sleeping.
  • Can cause weight gain, which can be helpful if you've recently lost weight or have a low appetite.
  • Effective at relieving depression and anxiety symptoms.
Coming soon.
  • Lowers relapse rates of depression.
  • Causes more sleepiness than other antidepressants, so it's good for people who have trouble sleeping.
  • Might work when other antidepressants haven't worked since it affects two chemicals in the brain that impact your mood. Many other antidepressants affect only serotonin, but not norepinephrine too.
  • Effective at relieving depression and anxiety symptoms.
Downsides and risks
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
  • When used for depression, Elavil (Amitriptyline) causes more side effects and has a higher risk of overdose than other antidepressants. It's usually used when other medications haven't worked.
  • It's more likely to cause sleepiness, nausea, constipation, diarrhea, and weight gain (1 to 5 pounds) than other antidepressants.
  • People age 65 and older have a higher risk for this medication's side effects.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people age 24 and younger.
  • Not a good option if you're a heavy drinker, or if you have liver or kidney problems.
  • Not the best option for people with high blood pressure.
  • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
Coming soon.
  • Can cause minor weight gain (1 to 5 pounds).
  • Celexa (Citalopram) can cause an irregular heartbeat if you take a high dose (40 mg a day, or more).
  • Not a good option for you if you have heart or liver problems.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24 years.
  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
  • Neurontin (Gabapentin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, or confusion.
  • You can't skip or miss doses since suddenly stopping Neurontin (Gabapentin) can cause seizures. This is even more likely if you drink alcohol, so it might not be the best medication for heavy drinkers.
  • More likely to cause diarrhea than other antidepressants.
  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
  • More likely to cause minor weight gain (1 to 5 pounds) and raise cholesterol than any other antidepressant.
  • Not as effective as other medications for depression.
  • More sedating than other antidepressants.
  • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
  • Side effects are usually manageable, but can be annoying.
  • Increases the risk of falls, especially when used in the elderly.
  • There's an increased chance of it causing heart problems, especially in people with a history of heart problems.
  • Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
  • Not as effective as other medications for depression.
  • More sedating than other antidepressants.
  • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
  • Can cause more sexual side effects like low libido and an inability to orgasm or ejaculate than most antidepressants.
  • More likely to cause minor weight gain (1 to 5 pounds) or make you feel sick if you miss a dose than other antidepressants.
  • Can harm an unborn child, so you can't take it if you're pregnant.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than age 24.
Coming soon.
  • Overdosing on this medication could be fatal.
  • It's more likely to cause nausea and vomiting or make you feel sick if you miss a dose than other antidepressants. Also causes more sleepiness than others.
  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
  • Not the best option for people with high blood pressure.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
Tips from our pharmacists for people taking the medication
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
  • Take at bedtime to avoid some of its side effects.
  • Can cause dizziness, drowsiness, constipation, and weight gain.
  • Stop taking it slowly to avoid getting withdrawal symptoms.
  • Full effects in 8 to 12 weeks for mood, 2 weeks for pain.
  • Take with food to avoid upset stomach.
  • Stop taking slowly to avoid withdrawal symptoms.
Coming soon.
  • Take with food to avoid upset stomach.
  • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
  • Stop taking it slowly to avoid getting withdrawal symptoms.
  • Side effects are common, but usually manageable.
  • Don't drive while taking Neurontin (Gabapentin) until you know how the medication affects you.
  • Neurontin and generic forms of Gabapentin have the same ingredients as Gralise and Horizant, but are dosed differently. Make sure you know which form you're taking since they are used for different purposes.
  • Take the extended-release tablet with food.
  • Stop taking Neurontin (Gabapentin) slowly over at least one week to avoid getting withdrawal symptoms.
  • It interacts with St. John's Wort and Tryptophan.
  • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
  • Stop taking it slowly to avoid getting withdrawal symptoms.
  • Can increase appetite and weight.
  • Takes 8 to 12 weeks to see full effects on mood.
  • Makes you sleepy. Take at bedtime.
  • Stop taking slowly to avoid withdrawal symptoms.
  • Needs to be taken every day for 1 to 2 weeks to start feeling better, and for 6 to 8 weeks to see the full effect of the medication.
  • It's important to keep taking Pamelor (Nortriptyline) even when you feel your symptoms are getting better.
  • Take it with food and/or at bedtime to decrease the potential side effects.
  • If you decide to stop taking Pamelor (Nortriptyline), work with your doctor to slowly get off this medicine to avoid getting withdrawal symptoms.
  • Can cause temporary dry mouth and upset stomach.
  • Seek medical attention for unwanted, persistent erection.
  • Makes you sleepy. Take at bedtime.
  • The controlled-release (CR) tablet can cause less nausea than other forms.
  • Don’t crush, break, or chew the Paxil (Paroxetine) controlled-release tablet or the Pexeva film-coated tablets.
  • It’s best to take Paxil (Paroxetine) in the morning, except Brisdelle, which can be taken at bedtime.
  • Take with food to avoid upset stomach.
  • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
  • Stop taking it slowly to avoid getting withdrawal symptoms.
Coming soon.
  • You can take the extended-release form once a day with food either in the morning or in the evening at about the same time each day.
  • Extended-release capsules should be swallowed whole. If you can’t swallow pills, open the capsule, sprinkle it on a spoonful of applesauce and then swallow it without chewing.
  • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
  • Stop taking it slowly to avoid getting withdrawal symptoms.
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