Prescription onlyLower-cost generic availableClass: Mental health

Elavil Alternatives

(Amitriptyline)

Prescription onlyLower-cost generic availableClass: Mental health
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Compare Elavil (Amitriptyline) to alternatives

These medications are comparable to Elavil (Amitriptyline) or used for similar purposes.

Elavil
(Amitriptyline)

Cymbalta
(Duloxetine)

Norpramin
(Desipramine)

Celexa
(Citalopram)

Neurontin
(Gabapentin)

Zoloft
(Sertraline)

Remeron
(Mirtazapine)

Pamelor
(Nortriptyline)

Oleptro
(Trazodone)

Paxil
(Paroxetine)

Tofranil
(Imipramine Hydrochloride)

Effexor
(Venlafaxine)

Improves mood and relieves certain kinds of pain. Elavil (Amitriptyline) is an older antidepressant that's sometimes used to treat pain and sleep problems, but it can have more side effects than similar medications.Improves mood and relieves certain kinds of pain. Cymbalta (Duloxetine) is good for treating depression and anxiety, and may help with chronic pain. More likely than other antidepressants to cause problems if you drink or have high blood pressure.Coming soon.Improves mood and helps you relax. Celexa (Citalopram) is good for treating depression and anxiety. Might be less likely to cause side effects than some antidepressants, but not the best choice for people with heart or liver problems.Treats tingling and burning nerve pain. Neurontin (Gabapentin) is an old seizure disorder medicine that's now used to treat nerve-related pain caused by different conditions.Improves mood and helps you relax. Zoloft (Sertraline) is good for treating depression and anxiety. It's more likely to cause insomnia and diarrhea than other antidepressants.Improves mood. Remeron (Mirtazapine) is okay for treating depression and good for sleep. More likely to cause weight gain than any other antidepressant.Improves your mood. Pamelor (Nortriptyline) is a good option for treating depression, especially for people who also have problems with persistent nerve pain.Improves mood and helps you sleep. Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.Improves mood and helps you relax. Paxil (Paroxetine) is good for treating depression and anxiety but it causes more weight gain, sleepiness, and withdrawal symptoms than other antidepressants.Coming soon.Improves mood and helps you relax. Effexor (Venlafaxine) is good for treating depression and anxiety. May work when other antidepressants haven't, it's but more likely to cause side effects and withdrawal symptoms than other antidepressants.
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Reviews & ratings
Filter group. All currently selected
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4.48Elavil
Reviews for Elavil (Amitriptyline)
53%
of people (All ages) say Elavil (Amitriptyline) is worth it
36%
say it works well
25%
say it's a big hassle
134 reviews
Have you used Elavil (Amitriptyline)?
Worth itNot sureNot worth it
Reviews for Cymbalta (Duloxetine)
58%
+5% better vs. Elavil (Amitriptyline)
49%
+13% better vs. Elavil (Amitriptyline)
24%
+1% better vs. Elavil (Amitriptyline)
496 reviews
Have you used Cymbalta (Duloxetine)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Norpramin (Desipramine)?
Worth itNot sureNot worth it
Reviews for Celexa (Citalopram)
61%
+8% better vs. Elavil (Amitriptyline)
51%
+15% better vs. Elavil (Amitriptyline)
16%
+9% better vs. Elavil (Amitriptyline)
520 reviews
Have you used Celexa (Citalopram)?
Worth itNot sureNot worth it
Reviews for Neurontin (Gabapentin)
57%
+4% better vs. Elavil (Amitriptyline)
40%
+4% better vs. Elavil (Amitriptyline)
19%
+6% better vs. Elavil (Amitriptyline)
620 reviews
Have you used Neurontin (Gabapentin)?
Worth itNot sureNot worth it
Reviews for Zoloft (Sertraline)
59%
+6% better vs. Elavil (Amitriptyline)
41%
+5% better vs. Elavil (Amitriptyline)
15%
+10% better vs. Elavil (Amitriptyline)
1472 reviews
Have you used Zoloft (Sertraline)?
Worth itNot sureNot worth it
Reviews for Remeron (Mirtazapine)
45%
-8% worse vs. Elavil (Amitriptyline)
39%
+3% better vs. Elavil (Amitriptyline)
26%
-1% worse vs. Elavil (Amitriptyline)
152 reviews
Have you used Remeron (Mirtazapine)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Pamelor (Nortriptyline)?
Worth itNot sureNot worth it
Reviews for Oleptro (Trazodone)
73%
+20% better vs. Elavil (Amitriptyline)
49%
+13% better vs. Elavil (Amitriptyline)
24%
+1% better vs. Elavil (Amitriptyline)
Have you used Oleptro (Trazodone)?
Worth itNot sureNot worth it
Reviews for Paxil (Paroxetine)
52%
-1% worse vs. Elavil (Amitriptyline)
39%
+3% better vs. Elavil (Amitriptyline)
24%
+1% better vs. Elavil (Amitriptyline)
694 reviews
Have you used Paxil (Paroxetine)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Tofranil (Imipramine Hydrochloride)?
Worth itNot sureNot worth it
Reviews for Effexor (Venlafaxine)
62%
+9% better vs. Elavil (Amitriptyline)
51%
+15% better vs. Elavil (Amitriptyline)
23%
+2% better vs. Elavil (Amitriptyline)
577 reviews
Have you used Effexor (Venlafaxine)?
Worth itNot sureNot worth it
Side effects
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor

The Elavil FDA package insert doesn’t have numbers about how common side effects are.

More about Elavil side effects »
  • Nausea 15%
  • Headache 2%
  • Dry mouth 8%
  • Somnolencee 7%
  • Fatigue 4%
  • Sleep difficulty 4%
  • Constipation 5%
  • Dizziness 4%
  • Diarrhea 3%
  • Decreased appetite 5%
More Cymbalta side effects »

We haven’t found good data for Norpramin side effects.

FDA side effect reports for Norpramin »
  • Nausea 7%
  • Dry mouth 6%
  • Drowsiness 8%
  • Sleep difficulty 1%
  • Sweating increased 2%
  • Diarrhea 3%
  • Tremor 2%
  • Ejaculation disorder 5%
  • Inflammation inside the nose 1%
  • Indigestion 1%
More Celexa side effects »
  • Dizziness 21%
  • Drowsiness 16%
  • Leg or ankle swelling 6%
  • Muscle weakness 1%
  • Diarrhea 2%
  • Infection 2%
  • Dry mouth 3%
  • Constipation 2%
  • Accidental injury 2%
  • Vomiting 2%
More Neurontin side effects »
  • Nausea 10%
  • Diarrhea/loose stools 6%
  • Sleep difficulty 2%
  • Mouth dry 7%
  • Fatigue 10%
  • Dizziness 2%
  • Feeling unwell 2%
  • Indigestion 4%
  • Loss of appetite 5%
  • Lower sex drive 2%
More Zoloft side effects »
  • Drowsiness 36%
  • Dry mouth 10%
  • Increased appetite 15%
  • Constipation 6%
  • Weight gain 10%
  • Muscle weakness 3%
  • Dizziness 4%
  • Flu syndrome 2%
  • Abnormal dreams 3%
  • Thinking abnormal 2%
More Remeron side effects »

We haven’t found good data for Pamelor side effects.

FDA side effect reports for Pamelor »
  • Somnolence/sedation 27%
  • Drowsiness 21%
  • Dry mouth 14%
  • Headache 6%
  • Dizziness/lightheadedness 13%
  • Dizziness 13%
  • Nausea 8%
  • Fatigue 7%
More Oleptro side effects »
  • Nausea 17%
  • Drowsiness 14%
  • Dry mouth 6%
  • Headache 1%
  • Muscle weakness 9%
  • Constipation 5%
  • Sleep difficulty 7%
  • Ejaculatory disturbance‡§ 13%
  • Dizziness 7%
  • Diarrhea 4%
More Paxil side effects »

We haven’t found good data for Tofranil side effects.

FDA side effect reports for Tofranil »
  • Nausea 24%
  • Dizziness 19%
  • Sleep difficulty 10%
  • Drowsiness 14%
  • Muscle weakness 12%
  • Loss of appetite 12%
  • Nervousness 10%
  • Sweating 7%
  • Abnormality of accommodation 8%
  • Indigestion 5%
More Effexor side effects »
How it works
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
Elavil (Amitriptyline) is a tricyclic antidepressant (TCA). Researchers don't know exactly how it works. It may change serotonin and norepinephrine activity in the brain, which regulates mood and pain perception. It also has sedative effects.Cymbalta (Duloxetine) is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. It increases serotonin and norepinephrine activity in the brain, which regulates mood.Coming soon.Celexa (Citalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Neurontin (Gabapentin) is an antiepileptic and nerve pain reliever. Researchers don't know exactly how it works, but it has a similar structure to GABA, a neurotransmitter that calms nerves in the brain and spinal cord.Zoloft (Sertraline) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases the activity of serotonin in the brain, which regulates mood.Remeron (Mirtazapine) is an atypical antidepressant. It stimulates your body to make certain chemicals in the brain, such as serotonin and norepinephrine, which regulate mood.Pamelor (Nortriptyline) is a tricyclic antidepressant (TCA). It helps improve your mood by altering the levels of serotonin, norepinephrine, and other similar chemicals in your brain.Oleptro (Trazodone) is a serotonin reuptake inhibitor (SRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Paxil (Paroxetine) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Coming soon.Effexor (Venlafaxine) is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. It increases serotonin and norepinephrine activity in the brain, which regulate mood.
Type of medication
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Prescription only
Available as
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
  • Pill
  • Extended release
  • Pill
  • Pill
  • Oral solution
  • Pill
  • Oral solution
  • Pill
  • Liquid
  • Pill
  • Dissolving tablet
  • Pill
  • Liquid
  • Pill
  • Extended release
  • Pill
  • Extended release tablet
  • Liquid
  • Pill
  • Pill
  • Extended release
Used for
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
  • Depression
  • Depression Nocturnal Enuresis
Risk factors for serious side effects
ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
  • Age 24 years or younger
  • History of bipolar disorder
  • At risk for bipolar disorder
  • History of cardiovascular disease
  • Age 65 years or older
  • Age 65 years or older
Detailed Elavil (Amitriptyline) risks & warnings »
  • Age 24 years or younger
  • Using other medications that affect serotonin
  • Stopping Cymbalta (Duloxetine) suddenly
  • History of high blood pressure
  • Taking other blood-thinning drugs
    • History of bipolar disorder
    • At risk for bipolar disorder
    Detailed Cymbalta (Duloxetine) risks & warnings »
    Coming soon.
    • Age 24 years or younger
    • Using other medications that affect serotonin
    • History of bipolar disorder
    • At risk for bipolar disorder
    • Stopping Celexa (Citalopram) suddenly
    • Higher dose
    • History of heart problems
    • History of liver problems
    • Older age
    • Taking other blood-thinning drugs
      Detailed Celexa (Citalopram) risks & warnings »
        • Children ages 3 to 12
          • Taking with alcohol or drugs
          • Stopping Neurontin (Gabapentin) suddenly
          Detailed Neurontin (Gabapentin) risks & warnings »
          • Under 24 years old
          • Interactions with other medications
              • Stopping Zoloft (Sertraline) suddenly
              • Taking with blood-thinning drugs
              • Elderly
              • Taking with diuretic medications
              Detailed Zoloft (Sertraline) risks & warnings »
              • Age 24 years or younger
              • Using other medications that affect serotonin
              • History of heart problems
              • History of liver problems
              • Higher dose
              • Alcohol
              • Taking other medicines that make you less alert
                  Detailed Remeron (Mirtazapine) risks & warnings »
                  • Age 24 years or younger
                  • Age 65 years or older
                  • Stopping Pamelor (Nortriptyline) suddenly
                  • Using other medications that affect serotonin
                  • History of heart disease
                  • Older age
                  • Electrolyte imbalance
                  Detailed Pamelor (Nortriptyline) risks & warnings »
                  • Age 24 years or younger
                  • History of seizures
                  • Alcoholism
                  • Eating disorder
                  • Higher dose
                  • Drug interactions
                    • Age 65 years or older
                    • Alcohol
                    • Taking other medicines that make you less alert
                    Detailed Oleptro (Trazodone) risks & warnings »
                    • Age 24 years or younger
                    • Using other medications that affect serotonin
                    • Stopping Paxil (Paroxetine) suddenly
                    • Taking other blood-thinning drugs
                      • History of bipolar disorder
                      • At risk for bipolar disorder
                        Detailed Paxil (Paroxetine) risks & warnings »
                        Coming soon.
                        • Age 24 years or younger
                        • Using other medications that affect serotonin
                        • Stopping Effexor (Venlafaxine) suddenly
                        • History of high blood pressure
                        • Taking other blood-thinning drugs
                          • History of bipolar disorder
                          • At risk for bipolar disorder
                          Detailed Effexor (Venlafaxine) risks & warnings »
                          Pregnancy

                          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                          The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

                          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                          The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

                          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                          The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

                          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                          Interactions
                          ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
                          No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.
                          • It interacts with St. John's Wort and Tryptophan.
                          No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.
                          Food
                          ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
                          No food related info.
                          • Take with food to avoid upset stomach.
                          No food related info.
                          • Take with food to avoid upset stomach.
                          • Take the extended-release tablet with food.
                          No food related info.No food related info.
                          • Take it with food and/or at bedtime to decrease the potential side effects.
                          No food related info.
                          • Take with food to avoid upset stomach.
                          No food related info.No food related info.
                          Kidneys and liver
                          ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
                          No kidneys and liver related info.
                          • Not a good option if you're a heavy drinker, or if you have liver or kidney problems.
                          No kidneys and liver related info.
                          • Not a good option for you if you have heart or liver problems.
                          No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.No kidneys and liver related info.
                          Pain
                          ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
                          • Low doses work well to treat certain kinds of chronic pain. It can take 2 weeks to feel the full effects of the medication.
                          • Full effects in 8 to 12 weeks for mood, 2 weeks for pain.
                          No pain related info.No pain related info.
                          • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
                          No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.
                          Sex
                          ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
                          No sex related info.No sex related info.No sex related info.
                          • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
                          No sex related info.
                          • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
                          No sex related info.No sex related info.No sex related info.No sex related info.No sex related info.
                          • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
                          Sleep
                          ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
                          • Can cause dizziness, drowsiness, constipation, and weight gain.
                          No sleep related info.No sleep related info.No sleep related info.
                          • Neurontin (Gabapentin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, or confusion.
                          • Causes less drowsiness than other antidepressants.
                          • Zoloft (Sertraline) may increase the risk of low sodium levels in the blood (hyponatremia). Watch out for symptoms including headache, difficulty concentrating, memory problems, confusion, weakness, and unsteadiness, which may lead to falls. Talk to a doctor right away before developing more serious symptoms, such as hallucination, fainting, coma, and death.
                          No sleep related info.No sleep related info.No sleep related info.
                          • It causes drowsiness, so it's good for people who have trouble sleeping.
                          No sleep related info.No sleep related info.
                          Weight
                          ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
                          • It's more likely to cause sleepiness, nausea, constipation, diarrhea, and weight gain (1 to 5 pounds) than other antidepressants.
                          No weight related info.No weight related info.
                          • Can cause minor weight gain (1 to 5 pounds).
                          No weight related info.No weight related info.
                          • More likely to cause minor weight gain (1 to 5 pounds) and raise cholesterol than any other antidepressant.
                          • Can increase appetite and weight.
                          • Remeron (Mirtazapine) can increase appetite and cause you to gain weight.
                          No weight related info.No weight related info.
                          • Can cause weight gain, which can be helpful if you've recently lost weight or have a low appetite.
                          • More likely to cause minor weight gain (1 to 5 pounds) or make you feel sick if you miss a dose than other antidepressants.
                          No weight related info.No weight related info.
                          Upsides and benefits
                          ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
                          • Low doses work well to treat certain kinds of chronic pain. It can take 2 weeks to feel the full effects of the medication.
                          • Low doses of Elavil (Amitriptyline) start working in 45 minutes to help you sleep better.
                          • Six out of every ten people who use an antidepressant for the first time find that it works for them.
                          • Effective at relieving depression and anxiety symptoms.
                          • Lowers relapse rates for depression.
                          • Can relieve some types of chronic pain. Might be particularly good at pain relief for people who are also depressed.
                          • Six out of ten people who use an antidepressant for the first time find that it works for them.
                          Coming soon
                          • Effective at relieving depression and anxiety symptoms.
                          • Causes less sleepiness compared to other antidepressants.
                          • Six out of ten people who use an antidepressant for the first time find that it works for them.
                          • Originally used to treat epilepsy (partial seizures), but now it primarily treats neuropathic pain that's caused by nerve stimulation or damage.
                          • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
                          • It's available as a generic, so it's less expensive than similar medications.
                          • Effective at lowering symptoms and relapse rates of depression and anxiety disorders.
                          • Causes less drowsiness than other antidepressants.
                          • Six out of ten people who use an antidepressant for the first time find that it works for them.
                          • Effective at relieving some depression symptoms.
                          • Starts to work more quickly than most antidepressants.
                          • Might be a good option for people who have insomnia with their depression, because it can make you very sleepy.
                          • Good option for people who are underweight or frail, because it can help you gain weight.
                          • Six out of ten people who use an antidepressant for the first time find that it works for them.
                          • Helpful with treating certain types of pain, like migraines or nerve-related pain.
                          • Generally well tolerated and has fewer side effects than other medicines in the same class of drugs.
                          • Commonly used in lower doses to help treat sleep problems (insomnia).
                          • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
                          • Fewer sexual side effects than many other antidepressants.
                          • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
                          • Comes as a generic medication and is cheaper than many other sleep aides.
                          • Six out of ten people who use an antidepressant for the first time find that it works for them.
                          • Effective at relieving depression and anxiety symptoms.
                          • Lowers relapse rates of depression and anxiety disorders, including OCD, panic disorder, social anxiety disorder, and generalized anxiety disorder.
                          • It causes drowsiness, so it's good for people who have trouble sleeping.
                          • Can cause weight gain, which can be helpful if you've recently lost weight or have a low appetite.
                          • Six out of ten people who use an antidepressant for the first time find that it works for them.
                          Coming soon
                          • Effective at relieving depression and anxiety symptoms.
                          • Lowers relapse rates of depression.
                          • Causes more sleepiness than other antidepressants, so it's good for people who have trouble sleeping.
                          • Six out of ten people who use an antidepressant for the first time find that it works for them.
                          • Might work when other antidepressants haven't worked since it affects two chemicals in the brain that impact your mood. Many other antidepressants affect only serotonin, but not norepinephrine too.
                          Downsides and risks
                          ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
                          • When used for depression, Elavil (Amitriptyline) causes more side effects and has a higher risk of overdose than other antidepressants. It's usually used when other medications haven't worked.
                          • It's more likely to cause sleepiness, nausea, constipation, diarrhea, and weight gain (1 to 5 pounds) than other antidepressants.
                          • People age 65 and older have a higher risk for this medication's side effects.
                          • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people age 24 and younger.
                          • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
                          • Not a good option if you're a heavy drinker, or if you have liver or kidney problems.
                          • Not the best option for people with high blood pressure.
                          • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
                          • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
                          Coming soon
                          • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
                          • Can cause minor weight gain (1 to 5 pounds).
                          • Celexa (Citalopram) can cause an irregular heartbeat if you take a high dose (40 mg a day, or more).
                          • Not a good option for you if you have heart or liver problems.
                          • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24 years.
                          • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
                          • Neurontin (Gabapentin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, or confusion.
                          • You can't skip or miss doses since suddenly stopping Neurontin (Gabapentin) can cause seizures. This is even more likely if you drink alcohol, so it might not be the best medication for heavy drinkers.
                          • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
                          • More likely to cause diarrhea than other antidepressants.
                          • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
                          • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
                          • Not as effective as other medications for depression.
                          • More sedating than other antidepressants.
                          • More likely to cause minor weight gain (1 to 5 pounds) and raise cholesterol than any other antidepressant.
                          • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
                          • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
                          • Side effects are usually manageable, but can be annoying.
                          • Increases the risk of falls, especially when used in the elderly.
                          • There's an increased chance of it causing heart problems, especially in people with a history of heart problems.
                          • Not as effective as other medications for depression.
                          • More sedating than other antidepressants.
                          • Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
                          • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
                          • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
                          • Can cause more sexual side effects like low libido and an inability to orgasm or ejaculate than most antidepressants.
                          • More likely to cause minor weight gain (1 to 5 pounds) or make you feel sick if you miss a dose than other antidepressants.
                          • Can harm an unborn child, so you can't take it if you're pregnant.
                          • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than age 24.
                          • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
                          Coming soon
                          • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
                          • Not the best option for people with high blood pressure.
                          • Overdosing on this medication could be fatal.
                          • It's more likely to cause nausea and vomiting or make you feel sick if you miss a dose than other antidepressants. Also causes more sleepiness than others.
                          • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
                          • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
                          Tips from our pharmacists for people taking the medication
                          ElavilCymbaltaNorpraminCelexaNeurontinZoloftRemeronPamelorOleptroPaxilTofranilEffexor
                          • Take at bedtime to avoid some of its side effects.
                          • Can cause dizziness, drowsiness, constipation, and weight gain.
                          • Stop taking it slowly to avoid getting withdrawal symptoms.
                          • Tell your doctor if you notice sudden mood changes or unusual thoughts.
                          • Take with food to avoid upset stomach.
                          • Full effects in 8 to 12 weeks for mood, 2 weeks for pain.
                          • Stop taking slowly to avoid withdrawal symptoms.
                          • Tell your doctor if you notice sudden mood changes or unusual thoughts.
                          Coming soon
                          • Take with food to avoid upset stomach.
                          • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
                          • Stop taking it slowly to avoid getting withdrawal symptoms.
                          • Tell your doctor if you notice sudden mood changes or unusual thoughts.
                          • Side effects are common, but usually manageable.
                          • Don't drive while taking Neurontin (Gabapentin) until you know how the medication affects you.
                          • Neurontin and generic forms of Gabapentin have the same ingredients as Gralise and Horizant, but are dosed differently. Make sure you know which form you're taking since they are used for different purposes.
                          • Take the extended-release tablet with food.
                          • Stop taking Neurontin (Gabapentin) slowly over at least one week to avoid getting withdrawal symptoms.
                          • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
                          • It interacts with St. John's Wort and Tryptophan.
                          • Stop taking it slowly to avoid getting withdrawal symptoms.
                          • Tell your doctor if you notice sudden mood changes or unusual thoughts.
                          • Makes you sleepy. Take at bedtime.
                          • Can increase appetite and weight.
                          • Takes 8 to 12 weeks to see full effects on mood.
                          • Stop taking slowly to avoid withdrawal symptoms.
                          • Tell your doctor if you notice sudden mood changes or unusual thoughts.
                          • Needs to be taken every day for 1 to 2 weeks to start feeling better, and for 6 to 8 weeks to see the full effect of the medication.
                          • It's important to keep taking Pamelor (Nortriptyline) even when you feel your symptoms are getting better.
                          • Take it with food and/or at bedtime to decrease the potential side effects.
                          • Tell your doctor if you notice sudden mood changes or unusual thoughts.
                          • If you decide to stop taking Pamelor (Nortriptyline), work with your doctor to slowly get off this medicine to avoid getting withdrawal symptoms.
                          • Makes you sleepy. Take at bedtime.
                          • Can cause temporary dry mouth and upset stomach.
                          • Seek medical attention for unwanted, persistent erection.
                          • Tell your doctor if you notice sudden mood changes or unusual thoughts.
                          • Take with food to avoid upset stomach.
                          • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
                          • Stop taking it slowly to avoid getting withdrawal symptoms.
                          • Tell your doctor if you notice sudden mood changes or unusual thoughts.
                          • The controlled-release (CR) tablet can cause less nausea than other forms.
                          • Don’t crush, break, or chew the Paxil (Paroxetine) controlled-release tablet or the Pexeva film-coated tablets.
                          • It’s best to take Paxil (Paroxetine) in the morning, except Brisdelle, which can be taken at bedtime.
                          Coming soon
                          • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
                          • You can take the extended-release form once a day with food either in the morning or in the evening at about the same time each day.
                          • Extended-release capsules should be swallowed whole. If you can’t swallow pills, open the capsule, sprinkle it on a spoonful of applesauce and then swallow it without chewing.
                          • Stop taking it slowly to avoid getting withdrawal symptoms.
                          • Tell your doctor if you notice sudden mood changes or unusual thoughts.
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                          More about ElavilSide effectsReviews & ratingsAlternativesFDA package insert
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