5.3/ 7 average rating with 19 reviewsforEliquis

Eliquis
Alternatives

(apixaban)

Eliquis (apixaban)

Prescription only

Aspirin

Over-the-counter
1 of 4 alternatives
Prevents blood clots.

Eliquis (apixaban) is an effective way to prevent blood clots from forming in your veins, but you have to take it twice a day, and your doctor might have to change the dose a lot.

Relieves pain, fever, and inflammation. Protects your heart and thins blood.

A low dose of Aspirin (81mg) every day can protect your heart, but it's not the best medicine to take for pain, swelling, or fever.

Upsides
  • Eliquis (apixaban) is very effective in reducing the risk of stroke in people with atrial fibrilation or other clotting disorders.
  • You don't need to have regular blood tests on Eliquis (apixaban), and you don't have to regulate your diet like other blood thinners.
  • If you've had clots in your legs or lungs before, Eliquis (apixaban) can lower the risk of these forming again.
  • When taking low doses (81 mg) every day, Aspirin provides protection for your heart and prevents heart attacks and stroke.
  • Used in higher doses to relieve pain, swelling, and fever.
  • Available over-the-counter in drugstores by itself and in combination with other cold and flu medications.
Downsides
  • You can bruise easier and if you cut yourself, it'll take longer to stop the bleeding. Always look for signs of internal bleeding, such as dark urine or bloody stools.
  • Can't be used if you have artificial heart valves.
  • Never stop taking Eliquis (apixaban) without talking to your doctor first.
  • Eliquis (apixaban) isn't available as a generic, so it can be expensive.
  • If you've taken too much Eliquis (apixaban) and you're bleeding, it can be harder to treat compared to other blood thinners.
  • Not a preferred medication for treating pain, swelling, or fever due to its high risk of bleeding.
  • NSAIDs (like ibuprofen and naproxen) and acetaminophen (Tylenol) are better for treating pain and fever thank Aspirin.
  • Aspirin raises your risk of bleeding, especially when used with other blood thinner medications like warfarin (Coumadin).
  • Studies show that using higher doses of Aspirin (162 mg or more) every day raises your risk of stomach bleeding and doesn't provide any additional heart protection.
Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
19 
47%
think this treatment is worth it
58%
think this treatment works well
21%
think this treatment is a hassle

Have you used Eliquis (apixaban)?

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533 
76%
think this treatment is worth it
41%
think this treatment works well
6%
think this treatment is a hassle

Have you used Aspirin?

Leave a review
Side effects
1possible side effects
  • Major bleed
    2%
See more detailed side effects
The Aspirin FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Increased risk of stroke or blood clots from early discontinuation

    Stopping Eliquis (apixaban) prematurely

  • Paralysis in the spine

    Spinal puncture (spinal tap)

    ...and 3 more risk factors

  • Increased risk of stroke or bleeding

    Artificial heart valve

  • Increased side effects in kidney or liver conditions

    Current kidney problems

    ...and 1 more risk factors

See more detailed risks and warnings
  • Brain damage or death from Reye's Syndrome

    Children 18 years or younger

    ...and 1 more risk factors

  • Stomach bleeding

    History of stomach bleeding or ulcers

    ...and 3 more risk factors

  • Serious allergic reactions

    Asthma

    ...and 4 more risk factors

  • Harm to unborn babies

    Women of childbearing age

See more detailed risks and warnings