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Vasotec Alternatives

(Enalapril)

Prescription onlyLower-cost generic available
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Compare Vasotec (Enalapril) to alternatives

These medications are comparable to Vasotec (Enalapril) or used for similar purposes.

Vasotec
(Enalapril)

Zestril
(Lisinopril)

Lotensin
(Benazepril)

Capoten
(Captopril)

Cozaar
(Losartan)

Norvasc
(Amlodipine)

Microzide
(Hydrochlorothiazide )

Lopressor
(Metoprolol Tartrate)

Toprol Xl
(Metoprolol Succinate)

Lowers blood pressure. Enalapril is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Zestril (Lisinopril) is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Benazepril is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Captopril is a good blood pressure-lowering medicine that protects kidney function, but you have to take it on an empty stomach.Lowers blood pressure. Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.Lowers blood pressure. Norvasc (Amlodipine) works well to lower blood pressure and prevent chest pain. You can't miss doses, and you might get persistent swelling.Lowers blood pressure. Removes extra water from your body. Microzide (Hydrochlorothiazide (Hctz)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Lowers blood pressure and controls heart rate. Lopressor (Metoprolol Tartrate) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.Lowers blood pressure and controls heart rate. Toprol Xl (Metoprolol Succinate) is good for controlling chest pain and treating heart failure and heart attack. You can't miss doses.
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Reviews & ratings
Filter group. All currently selected
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4.26Enalapril
Reviews for Vasotec (Enalapril)
44%
of people (All ages) say Vasotec (Enalapril) is worth it
40%
say it works well
21%
say it's a big hassle
Have you used Vasotec (Enalapril)?
Worth itNot sureNot worth it
Reviews for Zestril (Lisinopril)
61%
+17% vs. Vasotec (Enalapril)
51%
+11% vs. Vasotec (Enalapril)
14%
+7% vs. Vasotec (Enalapril)
687 reviews
Have you used Zestril (Lisinopril)?
Worth itNot sureNot worth it
Reviews for Lotensin (Benazepril)
61%
+17% vs. Vasotec (Enalapril)
64%
+24% vs. Vasotec (Enalapril)
23%
2% vs. Vasotec (Enalapril)
Have you used Lotensin (Benazepril)?
Worth itNot sureNot worth it
Reviews for Capoten (Captopril)
34%
10% vs. Vasotec (Enalapril)
25%
15% vs. Vasotec (Enalapril)
25%
4% vs. Vasotec (Enalapril)
106 reviews
Have you used Capoten (Captopril)?
Worth itNot sureNot worth it
Reviews for Cozaar (Losartan)
57%
+13% vs. Vasotec (Enalapril)
48%
+8% vs. Vasotec (Enalapril)
16%
+5% vs. Vasotec (Enalapril)
535 reviews
Have you used Cozaar (Losartan)?
Worth itNot sureNot worth it
Reviews for Norvasc (Amlodipine)
58%
+14% vs. Vasotec (Enalapril)
50%
+10% vs. Vasotec (Enalapril)
15%
+6% vs. Vasotec (Enalapril)
443 reviews
Have you used Norvasc (Amlodipine)?
Worth itNot sureNot worth it
Reviews for Microzide (Hydrochlorothiazide (Hctz))
47%
+3% vs. Vasotec (Enalapril)
31%
9% vs. Vasotec (Enalapril)
16%
+5% vs. Vasotec (Enalapril)
139 reviews
Have you used Microzide (Hydrochlorothiazide (Hctz))?
Worth itNot sureNot worth it
Reviews for Lopressor (Metoprolol Tartrate)
62%
+18% vs. Vasotec (Enalapril)
47%
+7% vs. Vasotec (Enalapril)
15%
+6% vs. Vasotec (Enalapril)
464 reviews
Have you used Lopressor (Metoprolol Tartrate)?
Worth itNot sureNot worth it
Reviews for Toprol Xl (Metoprolol Succinate)
60%
+16% vs. Vasotec (Enalapril)
54%
+14% vs. Vasotec (Enalapril)
13%
+8% vs. Vasotec (Enalapril)
164 reviews
Have you used Toprol Xl (Metoprolol Succinate)?
Worth itNot sureNot worth it
Side effects
EnalaprilLisinoprilBenazeprilCaptoprilLosartanNorvascHydrochlorothiazideLopressorToprol XL

The Enalapril FDA package insert doesn’t have numbers about how common side effects are.

More about Enalapril side effects »

The Lisinopril FDA package insert doesn’t have numbers about how common side effects are.

More about Lisinopril side effects »

The Benazepril FDA package insert doesn’t have numbers about how common side effects are.

More about Benazepril side effects »

The Captopril FDA package insert doesn’t have numbers about how common side effects are.

More about Captopril side effects »

The Losartan FDA package insert doesn’t have numbers about how common side effects are.

More about Losartan side effects »
  • Swelling due to excess fluid 10%
  • Dizziness 1%
More Norvasc side effects »

The Hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about Hydrochlorothiazide side effects »

The Lopressor FDA package insert doesn’t have numbers about how common side effects are.

More about Lopressor side effects »
  • Abnormally slow heartbeat 9%
  • Low blood pressure 4%
  • Heart block 3%
More Toprol XL side effects »
How it works
EnalaprilLisinoprilBenazeprilCaptoprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
Enalapril is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Zestril (Lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Benazepril is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Captopril is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Cozaar (Losartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Norvasc (Amlodipine) is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Microzide (Hydrochlorothiazide (Hctz)) is a thiazide diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Lopressor (Metoprolol Tartrate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Toprol Xl (Metoprolol Succinate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
EnalaprilLisinoprilBenazeprilCaptoprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
Angiotensin receptor blocker
Prescription only
Antihypertensive
Calcium channel blocker
Prescription only
Antihypertensive
Diuretic
Prescription only
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Beta blocker
Prescription only
Available as
EnalaprilLisinoprilBenazeprilCaptoprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
  • Pill
  • Liquid
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
  • Pill
  • Extended release
Used for (click to learn more)
EnalaprilLisinoprilBenazeprilCaptoprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
Risk factors for serious side effects
EnalaprilLisinoprilBenazeprilCaptoprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed risks & warnings »
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed risks & warnings »
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed risks & warnings »
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed risks & warnings »
  • Women of childbearing age
  • Concurrent liver disease
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed risks & warnings »
  • Age 65 years or older
  • History of heart problems
  • Liver disease
  • History of blood vessel disease
  • History of heart failure
Detailed risks & warnings »
  • Current electrolyte imbalance
  • History of sulfa allergies
  • History of gout
  • Current kidney problems
Detailed risks & warnings »
  • Diabetes
  • Coronary artery disease
  • Heart failure
  • Major surgery requiring anesthesia
  • History of asthma
Detailed risks & warnings »
  • Diabetes
  • Coronary artery disease
  • Heart failure
  • Major surgery requiring anesthesia
  • History of asthma
Detailed risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
EnalaprilLisinoprilBenazeprilCaptoprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
No interactions related info.No interactions related info.No interactions related info.No interactions related info.No interactions related info.
  • Interacts with the cholesterol medicine Simvastatin.
No interactions related info.No interactions related info.No interactions related info.
Food
EnalaprilLisinoprilBenazeprilCaptoprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
No food related info.No food related info.No food related info.No food related info.No food related info.No food related info.No food related info.
  • Take it with food.
No food related info.
Kidneys and liver
EnalaprilLisinoprilBenazeprilCaptoprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
  • Might not be a good choice if you have liver disease.
  • Your body uses your liver to break down Norvasc (Amlodipine) and remove it from your blood. If you have liver disease you may not be able to remove Norvasc (Amlodipine) as quickly from your blood as someone with a healthy liver. You should increase the dose of Norvasc (Amlodipine) slowly and watch closely for how it is working in your body. Increasing the dose slowly will lower your chances of having side effects.
  • Requires routine blood tests to check kidney function.
No kidneys and liver related info.No kidneys and liver related info.
Pain
EnalaprilLisinoprilBenazeprilCaptoprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
No pain related info.No pain related info.No pain related info.No pain related info.No pain related info.
  • Worsening heart pain or increased risk of heart attack is possible when you first start taking Norvasc (Amlodipine). This can also happen after you increase the dose of Norvasc (Amlodipine). Notify your doctor immediately if you experience any heart pain, radiating jaw pain, crushing chest pain, or persistent racing heartbeat.
No pain related info.No pain related info.No pain related info.
Upsides and benefits
EnalaprilLisinoprilBenazeprilCaptoprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
  • The only ACE inhibitor that doctors can give through an IV if that's needed.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Each dose lasts longer than other calcium channel blockers, which keeps blood pressure consistent without big ups and downs.
  • Particularly good at lowering systolic blood pressure (the top number), so it's a good option for older people who can commonly get high blood pressure only in the top number.
  • Works well to get rid of extra fluids in your body through urination.
  • A first-choice blood pressure treatment for many people. Works especially well for African Americans.
  • Good option if you have both high blood pressure and heart failure.
  • Raises calcium levels in the body, so it can be good for people with osteoporosis to slow down bone loss and even help with new bone formation.
  • Most people have very few side effects.
  • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for heart failure. May prevent long-term heart damage.
  • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
  • Toprol XL is the extended release version of Lopressor.
  • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for heart failure. May prevent long-term heart damage.
  • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
Downsides and risks
EnalaprilLisinoprilBenazeprilCaptoprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
  • Compared to other ACE inhibitors, less flexible on when you take it. Enalapril needs to be taken multiple times a day on an empty stomach.
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Compared to other ACE inhibitors, less flexible on when and how you take it. Captopril needs to be taken multiple times a day on an empty stomach.
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Amlodipine than men.
  • Some people might experience flushing with this medication.
  • You can't miss doses. Stopping Amlodipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • If you have severe heart disease, using Amlodipine might increase your risk of chest pain or heart attack during the time right after starting the medication or raising the dosage.
  • Might not be a good choice if you have liver disease.
  • Makes you urinate more often.
  • Doesn't work well in people with severe kidney problems.
  • Metoprolol tartrate is the immediate release version of Toprol XL. You have to take Metoprolol tartrate with food for it to work best. (On the other hand, you can take Toprol XL any time.)
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • You can't miss doses. Stopping Metoprolol tartrate suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease.
  • You can't miss doses. Stopping Toprol XL suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Can hide symptoms of low blood sugar if you're diabetic.
Tips from our pharmacists for people taking the medication
EnalaprilLisinoprilBenazeprilCaptoprilLosartanNorvascHydrochlorothiazideLopressorToprol XL
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Don't take it if you're pregnant.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Don't take it if you're pregnant.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Don't take it if you're pregnant.
  • Take 1 hour before or 2 hours after eating.
  • Tell your doctor about any dizziness, fatigue, cough, or change in taste sensation that doesn't go away.
  • Don't take it if you're pregnant.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Don't take it if you're pregnant.
  • Interacts with the cholesterol medicine Simvastatin.
  • Can cause ankle or foot swelling.
  • Can cause gum overgrowth. Ask your dentist to check for this side effect.
  • Starts working in about 2 hours.
  • Makes you urinate more often, so avoid taking it at bedtime.
  • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
  • Take it with food.
  • This is the immediate release version. It also comes as an extended release form: Toprol XL (metoprolol succinate).
  • Can cause fatigue and headache.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly.
  • Extended release version. Also comes in immediate release called Lopressor (metoprolol tartrate).
  • Can cause fatigue and headache.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly.
Learn more
More about EnalaprilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Vasotec (Enalapril)?
Worth itNot sureNot worth it
More about LisinoprilSide effectsReviews & ratingsFDA package insert
Have you used Zestril (Lisinopril)?
Worth itNot sureNot worth it
More about BenazeprilSide effectsReviews & ratingsFDA package insert
Have you used Lotensin (Benazepril)?
Worth itNot sureNot worth it
More about CaptoprilSide effectsReviews & ratingsFDA package insert
Have you used Capoten (Captopril)?
Worth itNot sureNot worth it
More about LosartanSide effectsReviews & ratingsFDA package insert
Have you used Cozaar (Losartan)?
Worth itNot sureNot worth it
More about NorvascSide effectsReviews & ratingsFDA package insert
Have you used Norvasc (Amlodipine)?
Worth itNot sureNot worth it
More about HydrochlorothiazideSide effectsReviews & ratingsFDA package insert
Have you used Microzide (Hydrochlorothiazide (Hctz))?
Worth itNot sureNot worth it
More about LopressorSide effectsReviews & ratingsFDA package insert
Have you used Lopressor (Metoprolol Tartrate)?
Worth itNot sureNot worth it
More about Toprol XLSide effectsReviews & ratingsFDA package insert
Have you used Toprol Xl (Metoprolol Succinate)?
Worth itNot sureNot worth it