Endometrin

(progesterone vaginal insert)

3.0/ 5 average rating with 55 reviewsforEndometrin
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Supports other fertility treatments.

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Our bottom line

Endometrin (progesterone vaginal insert) is a vaginal insert used in fertility treatments, but you have to apply it more often than progesterone vaginal gel.

Quick facts about Endometrin
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available
Prices and discounts
Lowest price for 21 100mg inserts
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$235.34

Upsides

  • Helps increase your chances of getting pregnant.
  • Exposes your body to less hormone compared to progesterone pills or injections.
  • Endometrin (progesterone vaginal insert) replaces low levels of progesterone to prepare the lining of your uterus to receive and nourish a fertilized egg.
  • Endometrin (progesterone vaginal insert) comes with step-by-step instructions and is easy to use. Unlike some progesterone products that must be inserted lying down, Endometrin (progesterone vaginal insert) can be inserted while you are standing, sitting, or lying on your back with your knees bent.

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What to expect from Endometrin, on one page

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People’s experience with Endometrin

55reviews so far. What do you think?

Downsides

  • Endometrin (progesterone vaginal insert) can cause vaginal irritation and burning.
  • Inserting the applicator can possibly cause discomfort or infection.
  • Endometrin (progesterone vaginal insert) is dosed 2 to 3 times a day, compared to other progesterone products that are dosed 1 to 2 times a day.
  • You can't use tampons or other vaginal products for at least 6 hours before and 6 hours after using Endometrin (progesterone vaginal insert).
  • Only available as brand name, so it may be expensive.

Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Endometrin, on one page

Download Fact Sheet
Prices and discounts
Lowest price for 21 100mg inserts
Determining your location...
$235.34
How it works

Endometrin (progesterone vaginal insert) contains progesterone, an essential hormone for pregnancy. Progesterone prepares the uterus to receive and nourish a fertilized egg.

Quick facts about Endometrin
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Vaginal insert
People’s experience with Endometrin

55reviews so far. What do you think?

What to expect when you take Endometrin (progesterone vaginal insert) for Female infertility

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Side effect rates for Endometrin (progesterone vaginal insert)

From 404 clinical trials of Endometrin when taken for female infertility (100 mg three times daily)
  • Pain after egg harvesting
  • Stomach pain
  • Nausea
  • Overstimulation of ovaries
  • Stomach bloating and swelling
  • Constipation
  • Fatigue
  • Headache
  • Uterine spasm
  • Vaginal bleeding

Risks and Warnings for Endometrin (progesterone vaginal insert)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • History of heart disease
    • History of blood clots

    Endometrin (progesterone vaginal insert) should not be taken if you've had a heart attack, have heart disease, or have blood clots, since the medicine can make it worse. Tell your doctor before starting this medicine if you have a personal history of heart problems or blood clots. Go to the emergency room right away if you notice chest pain, difficulty breathing, or extreme pain in any of your limbs.