Prescription onlyNo lower cost generic available

Endometrin

(Progesterone Vaginal Insert)

  • Vaginal insert
  • Female infertility
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Supports fertility treatments.

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Prescription onlyNo lower cost generic available

Our pharmacists’ bottom line

Endometrin (Progesterone Vaginal Insert) is a vaginal insert used in fertility treatments, but you have to apply it more often than progesterone vaginal gel.

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  • Helps increase your chances of getting pregnant.
  • Regulates your menstrual cycle.
  • Exposes your body to less hormone compared to progesterone pills or injections.
  • Endometrin (Progesterone Vaginal Insert) replaces low levels of progesterone to prepare the lining of your uterus to receive and nourish a fertilized egg.
  • Endometrin (Progesterone Vaginal Insert) comes with step-by-step instructions and is easy to use. Unlike some progesterone products that make you to lie down when inserting them, Endometrin (Progesterone Vaginal Insert) can be inserted while you are standing, sitting, or lying on your back with your knees bent.
  • Endometrin (Progesterone Vaginal Insert) can cause vaginal irritation and burning.
  • Inserting the applicator can possibly cause discomfort or infection.
  • Endometrin (Progesterone Vaginal Insert) is dosed 2 to 3 times a day, compared to other progesterone products that are dosed 1 to 2 times a day.
  • You can't use tampons or other vaginal products for at least 6 hours before and 6 hours after taking Endometrin (Progesterone Vaginal Insert).

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Side effects for Endometrin (Progesterone Vaginal Insert)

From clinical trials of Endometrin / Assisted Reproductive Technology treatment (100 mg) ( 404)

  • Post-oocyte retrieval painPost-oocyte retrieval pain28% for Endometrin vs.0% for placebo
  • Post-oocyte retrieval painPost-oocyte retrieval pain25% for Endometrin vs.0% for placebo
  • Abdominal painAbdominal pain12% for Endometrin vs.0% for placebo
  • Abdominal painAbdominal pain12% for Endometrin vs.0% for placebo
  • NauseaNausea8% for Endometrin vs.0% for placebo
  • Ovarian hyperstimulation syndromeOvarian hyperstimulation syndrome7% for Endometrin vs.0% for placebo
  • Ovarian hyperstimulation syndromeOvarian hyperstimulation syndrome7% for Endometrin vs.0% for placebo
  • NauseaNausea7% for Endometrin vs.0% for placebo
  • Abdominal distensionAbdominal distension4% for Endometrin vs.0% for placebo
  • HeadacheHeadache4% for Endometrin vs.0% for placebo

What to expect when you take Endometrin (Progesterone Vaginal Insert)

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Tips from our pharmacists
  • Read the information you get in the pharmacy about how to use Endometrin (Progesterone Vaginal Insert). The step-by-step instructions are really helpful to follow.
  • Each vaginal insert applicator is made for a single use and should be thrown away after you use it.

Risks and Warnings for Endometrin (Progesterone Vaginal Insert)

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    • Higher risk if:
    • Personal or family history of breast cancer

    It is not completely clear if progestin, like as Endometrin (Progesterone Vaginal Insert), increases your risk of breast cancer. There may be a higher risk if you have a history of breast cancer, so make sure to get routine breast exams.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Endometrin (Progesterone Vaginal Insert)

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The FDA category for this medication is N. It is advised that you: Unknown
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