Prescription onlyNo lower cost generic available

Endometrin Alternatives

(Progesterone Vaginal Insert)

  • Vaginal insert
  • Female infertility
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Compare Endometrin (Progesterone Vaginal Insert) to alternatives

These medications are comparable to Endometrin (Progesterone Vaginal Insert) or used for similar purposes.

Endometrin
(Progesterone Vaginal Insert)

Crinone
(Progesterone Vaginal Gel)

Supports fertility treatments. Endometrin (Progesterone Vaginal Insert) is a vaginal insert used in fertility treatments, but you have to apply it more often than progesterone vaginal gel.Regulates your menstrual cycle and supports fertility treatments. Crinone (Progesterone Vaginal Gel) is a long-acting vaginal gel used in fertility treatments, and you don't have to apply it as often as progesterone vaginal inserts.
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Reviews & ratings
Button Group. All currently active
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3.963636363636364Endometrin
Reviews for Endometrin (Progesterone Vaginal Insert)
45%
of people say Endometrin (Progesterone Vaginal Insert) is worth it
20%
say it works well
27%
say it's a big hassle

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Side effects
EndometrinProgesterone vaginal gel

The Endometrin FDA package insert doesn’t have numbers about how common side effects are.

More about Endometrin side effects »

The Progesterone vaginal gel FDA package insert doesn’t have numbers about how common side effects are.

More about Progesterone vaginal gel side effects »
How it works
EndometrinProgesterone vaginal gel
Endometrin (Progesterone Vaginal Insert) contains progesterone, one of the hormones essential for maintaining a pregnancy. Women on fertility treatment can take progesterone to prepare the lining of the uterus to receive and nourish a fertilized egg.Crinone (Progesterone Vaginal Gel) contains progesterone, one of the hormones essential for maintaining a pregnancy. Women on fertility treatment can take progesterone to prepare the lining of the uterus to receive and nourish a fertilized egg.
Type of medication
EndometrinProgesterone vaginal gel
ProgestinPrescription only
ProgestinPrescription only
Available as
EndometrinProgesterone vaginal gel
  • Vaginal insert
  • Vaginal cream, gel, or ointment
Used for (click to learn more)
EndometrinProgesterone vaginal gel
  • Female infertility
  • Female infertility
Risk factors for serious side effects
EndometrinProgesterone vaginal gel
  • Personal or family history of breast cancer
  • Family history of ovarian cancer
  • Personal or family history of blood clots
  • Smoking
  • Obesity
  • Hypertension
  • Diabetes
  • High cholesterol
  • Systemic lupus erythematosus (SLE)
  • Diabetes
  • Heart failure
  • Kidney problems
  • Obesity
Detailed Endometrin (Progesterone Vaginal Insert) risks & warnings »
Coming soon.
Pregnancy category
EndometrinProgesterone vaginal gel
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
EndometrinProgesterone vaginal gel
  • Endometrin (Progesterone Vaginal Insert) replaces low levels of progesterone to prepare the lining of your uterus to receive and nourish a fertilized egg.
  • Endometrin (Progesterone Vaginal Insert) comes with step-by-step instructions and is easy to use. Unlike some progesterone products that make you to lie down when inserting them, Endometrin (Progesterone Vaginal Insert) can be inserted while you are standing, sitting, or lying on your back with your knees bent.
  • Helps increase your chances of getting pregnant.
  • Regulates your menstrual cycle.
  • Exposes your body to less hormone compared to progesterone pills or injections.
  • Crinone (Progesterone Vaginal Gel) replaces low levels of progesterone to prepare the lining of your uterus to receive and nourish a fertilized egg. If you become pregnant, Crinone (Progesterone Vaginal Gel) can be used for another 10 to 12 weeks until your progesterone levels are high enough.
  • Women can also use Crinone (Progesterone Vaginal Gel) to treat secondary amenorrhea (the absence of menstrual cycles in women who used to have a regular period) due to a decrease in the hormone progesterone. Crinone (Progesterone Vaginal Gel) is used to bring the hormone levels back up to normal.
  • Helps increase your chances of getting pregnant.
  • Regulates your menstrual cycle.
  • Exposes your body to less hormone compared to progesterone pills or injections.
Downsides and risks
EndometrinProgesterone vaginal gel
  • Endometrin (Progesterone Vaginal Insert) can cause vaginal irritation and burning.
  • Endometrin (Progesterone Vaginal Insert) is dosed 2 to 3 times a day, compared to other progesterone products that are dosed 1 to 2 times a day.
  • You can't use tampons or other vaginal products for at least 6 hours before and 6 hours after taking Endometrin (Progesterone Vaginal Insert).
  • Inserting the applicator can possibly cause discomfort or infection.
  • Crinone (Progesterone Vaginal Gel) can cause vaginal irritation and burning.
  • Crinone (Progesterone Vaginal Gel) can cause a white vaginal discharge a few days after taking the medicine, so wearing a panty liner can make you feel more comfortable.
  • You can't use tampons or other vaginal products for at least 6 hours before and 6 hours after using Crinone (Progesterone Vaginal Gel).
  • Inserting the applicator can possibly cause discomfort or infection.
Tips from our pharmacists for people taking the medication
EndometrinProgesterone vaginal gel
  • Read the information you get in the pharmacy about how to use Endometrin (Progesterone Vaginal Insert). The step-by-step instructions are really helpful to follow.
  • Each vaginal insert applicator is made for a single use and should be thrown away after you use it.
  • Read the information you get at your pharmacy about how to use Crinone (Progesterone Vaginal Gel). The diagrams are really helpful and there are different instructions for women using the gel at high altitudes.
  • The dose of Crinone (Progesterone Vaginal Gel) will be different depending on what you’re using it for, so take it exactly the way your doctor tells you.
  • Crinone (Progesterone Vaginal Gel) is available as a vaginal gel in two different strengths, 4% and 8%. Using more of the 4% gel isn't the same as using the 8% strength.
  • Each vaginal gel applicator is made for a single use and should be thrown away after you use it. Don't worry if a small amount of gel is left in the applicator.
Learn more
More about EndometrinSide effectsReviews & ratingsAlternativesFDA package insert
More about Progesterone vaginal gelSide effectsFDA package insert