Prescription onlyLower-cost generic availableClass: Women's health

Estraderm 

(estradiol patch)

Prescription onlyLower-cost generic availableClass: Women's health
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Treats low estrogen, relieves menopause symptoms, and lowers your risk of osteoporosis.

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Our bottom line

The Estraderm (Estradiol Patch) needs to be replaced twice a week, and it may have fewer side effects than oral estrogen pills.

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Upsides

  • The Estraderm (Estradiol Patch) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen, like hot flashes and vaginal dryness.
  • The patch is good for people who don't want to take daily pills.
  • Can be worn while swimming, bathing, and showering.
  • By using a patch instead of a pill, there's a lower risk of side effects such as blood clots and stroke since lower amounts of estrogen are used in patches.
  • Lowers your risk of fractures by keeping your bones healthy. Make sure you also get enough calcium and Vitamin D.
  • Improves mood, energy, and mental alertness for some people.

Downsides

  • Only comes in 2 strengths.
  • You need to replace the Estraderm (Estradiol Patch) twice a week, compared to other patches that are once a week.
  • Patch can fall off.
  • Increases your risk of uterine and breast cancer.
  • If you have your uterus, you have to use the Estraderm (Estradiol Patch) with another hormone called progestin to lower your risk of uterine cancer.
  • Increases your risk of developing blood clots and stroke.
  • Can worsen other health conditions, like high cholesterol, asthma, diabetes, fluid retention, and migraines.
  • Can't be used in people with liver problems.
How it works

The Estraderm (Estradiol Patch) replaces an estrogen hormone, estradiol, that your body loses during and after menopause. Higher levels of estradiol relieve symptoms of low estrogen and menopause and prevent bone loss.

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Side effect rates for Estraderm (estradiol patch)

266 From clinical trials of Estradiol Patch / Estrogen replacement postmenopause (0.1 mg/day)
  • Breast pain
  • Urti
  • Abdominal pain
  • Headache
  • Pain
  • Swelling due to excess fluid
  • Back pain
  • Low mood disorder
  • Passing gas
  • Thick vaginal discharge

Risks and Warnings for Estraderm (estradiol patch)

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    • Higher risk if:
    • Using estrogen for more than one year

    Vaginal bleeding after menopause can be a warning sign of uterus (endometrial) cancer, so let your doctor know if you notice any unusual bleeding. When estrogen is prescribed to women after menopause who still have a uterus, progestin should be used with it to lower the risk of cancer. Low-dose vaginal estrogen products are often a better choice than oral pills for women 65 years or older who have vaginal symptoms.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Estraderm (estradiol patch)

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  • Can cause nausea, dizziness, bloating, and breast tenderness.