Prescription onlyNo lower cost generic available

Estrasorb

(Estradiol Topical)

  • Topical emulsion
  • Hot flashes and night sweats
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Relieves hot flashes due to menopause.

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Prescription onlyNo lower cost generic available

Our pharmacists’ bottom line

Estrasorb (Estradiol Topical) comes in pre-dosed packets that can be convenient to use, but have the same side effects as other estrogen products.

  • Pre-measured packets can be easily transported.
  • Estrasorb (Estradiol Topical) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen (hot flashes, vaginal dryness, low energy, irritability).
  • Good for people who don't want to take daily pills.
  • Fewer side effects than pills since lower amounts of estrogen are used in topical solutions.
  • Can lower your risk of fractures by keeping your bones healthy. Make sure you also get enough calcium and Vitamin D.
  • Increases your risk of endometrial and breast cancer.
  • If you have your uterus, you have to use Estrasorb (Estradiol Topical) with another hormone called progestin to lower your risk of uterine cancer.
  • Increases your risk of developing blood clots and stroke.
  • Can't be used in people with liver problems.
  • Possibily exposing other people to the estrogen before it is absorbed by your skin.
  • Can be expensive since it is only available as a brand name product.

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Side effects for Estrasorb (Estradiol Topical)

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These are side effects of Estrasorb (Estradiol Topical) reported to the FDA by people taking it, and by doctors and pharmacists.

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What to expect when you take Estrasorb (Estradiol Topical)

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Tips from our pharmacists
  • Use 2 packets each time, one on each leg. Don't put them on your face, breasts, vagina, or irritated skin.
  • Massage the content of the packets onto dry, clean skin on your legs (thigh to calf) until it's absorbed (takes about 3 minutes).
  • Let the gel dry before dressing or letting anyone touch the areas where you put the medicine.
  • Wash your hands well after applying the gel.
  • Can cause nausea, dizziness, bloating, and breast tenderness.
  • Tell your doctor about any unusual vaginal bleeding.
  • Get emergency care if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision.

Risks and Warnings for Estrasorb (Estradiol Topical)

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    • Higher risk if:
    • Using estrogen for more than one year

    Vaginal bleeding after menopause can be a warning sign of uterus (endometrial) cancer, so let your doctor know if you notice any unusual bleeding. When estrogen is prescribed to women after menopause who still have a uterus, progestin should be used with it to lower the risk of cancer. Low-dose vaginal estrogen products are often a better choice than oral pills for women 65 years or older who have vaginal symptoms.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Tips from pharmacists and people taking Estrasorb (Estradiol Topical)

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The FDA category for this medication is X. It is advised that you: Unsafe
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