Prescription onlyClass: Women's health


(estradiol topical)

Prescription onlyClass: Women's health
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Relieves hot flashes due to menopause.

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Our bottom line

Estrasorb (Estradiol Topical) comes in pre-dosed packets that can be convenient to use, but have the same side effects as other estrogen products.

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Prices and coupons for 1 (56 packets of 2.5mg/g) carton of estrasorb
What is GoodRx?


  • Pre-measured packets can be easily transported.
  • Estrasorb (Estradiol Topical) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen (hot flashes, vaginal dryness, low energy, irritability).
  • Good for people who don't want to take daily pills.
  • Fewer side effects than pills since lower amounts of estrogen are used in topical solutions.
  • Can lower your risk of fractures by keeping your bones healthy. Make sure you also get enough calcium and Vitamin D.
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  • Increases your risk of endometrial and breast cancer.
  • If you have your uterus, you have to use Estrasorb (Estradiol Topical) with another hormone called progestin to lower your risk of uterine cancer.
  • Increases your risk of developing blood clots and stroke.
  • Can't be used in people with liver problems.
  • Possibily exposing other people to the estrogen before it is absorbed by your skin.
  • Can be expensive since it is only available as a brand name product.
How it works

Estrasorb (Estradiol Topical) is a topical solution that replaces estrogen hormones in your vagina that your body loses during menopause. Estrogen helps relieve symptoms of menopause, such as hot flashes, night sweats, and vaginal problems.

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Side effect rates for Estrasorb (estradiol topical)

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These are side effects of Estrasorb (estradiol topical) reported to the FDA by people taking it, and by doctors and pharmacists.
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Risks and Warnings for Estrasorb (estradiol topical)

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    • Higher risk if:
    • Using estrogen for more than one year

    Vaginal bleeding after menopause can be a warning sign of uterus (endometrial) cancer, so let your doctor know if you notice any unusual bleeding. When estrogen is prescribed to women after menopause who still have a uterus, progestin should be used with it to lower the risk of cancer. Low-dose vaginal estrogen products are often a better choice than oral pills for women 65 years or older who have vaginal symptoms.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Estrasorb (estradiol topical)

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  • Can cause nausea, dizziness, bloating, and breast tenderness.